Patents by Inventor Sang-Bae Han

Sang-Bae Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9719989
    Abstract: The present invention relates to a method for detecting food poisoning bacteria, and more particularly, to a method for rapidly and quantitatively isolating food poisoning bacteria contents which contaminate food and the like. The method according to the present invention is characterized by including the steps of: introducing magnetic nanoparticles which can bind to bacteria into a sample for measuring the bacteria so as to bind the magnetic nanoparticles to the bacteria; isolating the magnetic nanoparticles; passing the nanoparticles which are isolated by using magnetism through a solution having high viscosity so as to separate the magnetic nanoparticles to which bacteria are bound from magnetic nanoparticles to which no bacteria are bound; and quantifying the magnetic nanoparticles to which bacteria are bound.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: August 1, 2017
    Assignees: POSTECH ACADEMY-INDUSTRY FOUNDATION, REPUBLIC OF KOREA (MINISTER OF FOOD AND DRUG SAFETY)
    Inventors: Sangmin Jeon, Dong-hoon Kwon, Jin myoung Joo, Ki hwan Park, Sang-Bae Han, Hwa-Jung Lee, Kyu-Heon Kim
  • Publication number: 20150293083
    Abstract: The present invention relates to a method for detecting food poisoning bacteria, and more particularly, to a method for rapidly and quantitatively isolating food poisoning bacteria contents which contaminate food and the like. The method according to the present invention is characterized by including the steps of: introducing magnetic nanoparticles which can bind to bacteria into a sample for measuring the bacteria so as to bind the magnetic nanoparticles to the bacteria; isolating the magnetic nanoparticles; passing the nanoparticles which are isolated by using magnetism through a solution having high viscosity so as to separate the magnetic nanoparticles to which bacteria are bound from magnetic nanoparticles to which no bacteria are bound; and quantifying the magnetic nanoparticles to which bacteria are bound.
    Type: Application
    Filed: November 26, 2013
    Publication date: October 15, 2015
    Inventors: Sangmin JEON, Dong-hoon KWON, Jin myoung JOO, Ki hwan PARK, Sang-Bae HAN, Hwa-Jung LEE, Kyu-Heon KIM
  • Patent number: 8975241
    Abstract: There is provided a composition for preventing and treating obesity including high water-soluble ?-cyclodextrin derivatives as an effective component. Specifically, the composition including the high water-soluble ?-cyclodextrin derivatives, especially, 2-hydroxypropyl-?-cyclodextrin (HP-?-CD, HPBCD) has effects on suppressing an increase in body weight induced by a high fat diet, suppressing appetite through decreasing an amount of dietary intake, decreasing body fat, decreasing liver weight, and significantly decreasing a sharp increase of blood sugar induced by intaking glucose and maltose on an empty stomach so that it can be useful for preventing and treating obesity, preventing and treating various diseases induced by obesity, and suppressing a sharp increase of blood sugar after dinner.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: March 10, 2015
    Assignee: Song Ho Biomed Co., Ltd.
    Inventors: Gyoon-Hee Han, Yong Seok Choi, Sang-Bae Han, Jong-Ho Lee, Hwan-Mook Kim, Song-Kyu Park, Ki-Ho Lee, Jong-Soon Kang, Ki-Hoon Lee, Chang-Woo Lee
  • Publication number: 20120196831
    Abstract: There is provided a composition for preventing and treating obesity including high water-soluble ?-cyclodextrin derivatives as an effective component. Specifically, the composition including the high water-soluble ?-cyclodextrin derivatives, especially, 2-hydroxypropyl-?-cyclodextrin (HP-?-CD, HPBCD) has effects on suppressing an increase in body weight induced by a high fat diet, suppressing appetite through decreasing an amount of dietary intake, decreasing body fat, decreasing liver weight, and significantly decreasing a sharp increase of blood sugar induced by intaking glucose and maltose on an empty stomach so that it can be useful for preventing and treating obesity, preventing and treating various diseases induced by obesity, and suppressing a sharp increase of blood sugar after dinner.
    Type: Application
    Filed: October 8, 2010
    Publication date: August 2, 2012
    Applicant: SONG HO BIOMED CO., LTD
    Inventors: Gyoon-Hee Han, Yong Seok Choi, Sang-Bae Han, Jong-Ho Lee, Hwan-Mook Kim, Song-Kyu Park, Ki-Ho Lee, Jong-Soon Kang, Ki-Hoon Lee, Chang-Woo Lee
  • Publication number: 20090087444
    Abstract: The present invention relates to a pharmaceutical composition for activating dendritic cells having polysaccharides from Angelica gigas Nakai as valid component. The angelan, polysaccharides separated from Angelica gigas Nakai, can improve the revelation of surface molecule of dendritic cells, the secret of cytokine of dendritic cells, the proliferation capability of T cells of dendritic cells, and the generation of cytokine such as IL-2.
    Type: Application
    Filed: September 29, 2006
    Publication date: April 2, 2009
    Inventors: Hwan-Mook Kim, Sang-Bae Han, Song-Kyu Park, Ki-Ho Lee, Jong-Soon Kang, Ki-Hoon Lee, Jee-Youn Kim, Chang-Woo Lee
  • Publication number: 20090048328
    Abstract: This invention relates to a composition for the prevention and treatment of acute graft-versus-host disease comprising prodigiosin isolated from Serratia marcescence B-1231 KCTC 0386BP, as an effective ingredient. The prodigiosin is immunosup-pressive by selectively suppressing the proliferation of T-cells through the suppression of the expression of IL-2 receptors, which is needed for the activation of T-cells. Prodigiosin can be used either alone or in conjunction with cyclosporin A for greater effect, since the two substances have different mode of actions. These make prodigiosin effective for the prevention and treatment of acute graft-versus-host disease.
    Type: Application
    Filed: July 10, 2006
    Publication date: February 19, 2009
    Applicant: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Hwan Mook Kim, Sang-Bae Han, Chang-Woo Lee, Ki-Hoon Lee, Sung-Kyu Park, Ki-Ho Lee, Jong-Soon Kang, Won-Kee Yoon, Young-Kook Kim
  • Patent number: 7462739
    Abstract: Disclosed are ceramide derivatives represented by the following formula 1 or 2, a method for preparing the same, and a therapeutic agent for treating atopic dermatitis including the ceramide derivatives as active ingredients: wherein, R1 and R2 are each independently straight or branched alkyl groups having 4 to 22 carbon atoms. The therapeutic agent for treating atopic dermatitis including the ceramide derivatives as active ingredients according to the present invention may be useful to treat atopic dermatitis, or treat other skin diseases that are required for improving skin inflammations or suppressing epidermal proliferation, by suppressing or improving inflammatory conditions in the atopic dermatitis in addition to giving immunoregulatory functions, and suppressing or improving skin disorders, for example epidermal proliferation that is generally observed in the atopic dermatitis.
    Type: Grant
    Filed: December 26, 2007
    Date of Patent: December 9, 2008
    Assignee: Neopharm Co., Ltd.
    Inventors: Byeong-Deog Park, Jong-Kyung Youm, Hyung-Sub Gwak, Mi-Jung Kwon, Hwan-Mook Kim, Jong-Soon Kang, Sang-Bae Han
  • Publication number: 20080161272
    Abstract: Disclosed are ceramide derivatives represented by the following formula 1 or 2, a method for preparing the same, and a therapeutic agent for treating atopic dermatitis including the ceramide derivatives as active ingredients: wherein, R1 and R2 are each independently straight or branched alkyl groups having 4 to 22 carbon atoms. The therapeutic agent for treating atopic dermatitis including the ceramide derivatives as active ingredients according to the present invention may be useful to treat atopic dermatitis, or treat other skin diseases that are required for improving skin inflammations or suppressing epidermal proliferation, by suppressing or improving inflammatory conditions in the atopic dermatitis in addition to giving immunoregulatory functions, and suppressing or improving skin disorders, for example epidermal proliferation that is generally observed in the atopic dermatitis.
    Type: Application
    Filed: December 26, 2007
    Publication date: July 3, 2008
    Inventors: Byeong-Deog Park, Jong-Kyung Youm, Hyung-Sub Gwak, Mi-Jung Kwon, Hwan-Mook Kim, Jong-Soon Kang, Sang-Bae Han
  • Patent number: 6943007
    Abstract: There is disclosed novel Phellinus linteus Yoo. This mushroom is identified as novel as analyzed by restriction fragment length polymorphism and by microbiological features. A polysaccharide substance isolated from the fruiting bodies or mycelia the strain and other Phellinus spp. has an anticancer activity by inciting the cytotoxicity of T-cells and the antibody forming potency of B-cells. Also, the polysaccharide substance shows a potent activity against cancer metastasis. The polysaccharide substance, which can stimulate the immunity of the body, may be effective in the prophylaxis and treatment of immune-related diseases, such as cancers and AIDS, and in the study on the basic mechanism of the diseases.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: September 13, 2005
    Assignee: Korea Institute of Science and Technology
    Inventors: Ick-Dong Yoo, Soo-Muk Cho, Byeung-Wook Park, Jae-Kuk Yoo, Nam-Doo Hong, Hwan-Mook Kim, Sang-Bae Han, Chang-Woo Lee
  • Publication number: 20010046972
    Abstract: There is disclosed novel Phellinus linteus Yoo. This mushroom is identified as novel as analyzed by restriction fragment length polymorphism and by microbiological features. A polysaccharide substance isolated from the fruiting bodies or mycelia the strain and other Phellinus spp. has an anticancer activity by inciting the cytotoxicity of T-cells and the antibody forming potency of B-cells. Also, the polysaccharide substance shows a potent activity against cancer metastasis. The polysaccharide substance, which can stimulate the immunity of the body, may be effective in the prophylaxis and treatment of immune-related diseases, such as cancers and AIDS, and in the study on the basic mechanism of the diseases.
    Type: Application
    Filed: May 1, 2001
    Publication date: November 29, 2001
    Applicant: KOREA INSTITUTE OF SCIENCE & TECHNOLOGY
    Inventors: Ick-Dong Yoo, Soo-Muk Cho, Byeung-Wook Park, Jae-Kuk Yoo, Nam-Doo Hong, Hwan-Mook Kim, Sang-Bae Han, Chang-Wood Lee
  • Patent number: 6030528
    Abstract: A waste water treatment plant for removing nitrogen and phosphorus is provided. The plant is operable by flow path change and intermittent aeration by the combination of at least two sets if intra-clarifier type oxidation ditches, external-clarifier type oxidation ditches or activated sludge processes.
    Type: Grant
    Filed: June 22, 1998
    Date of Patent: February 29, 2000
    Inventor: Sang-Bae Han