Patents by Inventor Sangeeta Bhargava

Sangeeta Bhargava has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusogenic, self-propagating blebs as immunogenic compositions
    Patent number: 7541038
    Abstract: Self-propagating, fusogenic blebs are produced from cells infected with a population of Venezuelan Equine Encephalitis virus replicon particles (VRP). The self-propagating, fusogenic nature of the blebs is derived from expression of heterologous genes encoding viral fusion proteins that are incorporated into the replication defective replicon particles. The resulting blebs can be harvested from supernatants of cells displaying severe cytopathic effects. The blebs are used to make immunogenic compositions and devise methods of immunizing mammals against paramyxoviruses such as parainfluenza virus type 3.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: June 2, 2009
    Assignee: Wyeth Holdings Corporation
    Inventors: Gerald Raul Kovacs, Xiaoyan Mo, Nikolaos Vasilakis, Sangeeta Bhargava, Timothy Joseph Zamb, Stephen Alexander Udem
  • Fusogenic, self-propagating blebs as immunogenic compositions
    Publication number: 20070128222
    Abstract: Self-propagating, fusogenic blebs are produced from cells infected with a population of Venezuelan Equine Encephalitis virus replicon particles (VRP). The self-propagating, fusogenic nature of the blebs is derived from expression of heterologous genes encoding viral fusion proteins that are incorporated into the replication defective replicon particles. The resulting blebs can be harvested from supernatants of cells displaying severe cytopathic effects. The blebs are used to make immunogenic compositions and devise methods of immunizing mammals against paramyxoviruses such as parainfluenza virus type 3.
    Type: Application
    Filed: June 2, 2004
    Publication date: June 7, 2007
    Applicant: Wyeth Holdings Corporation
    Inventors: Gerald Kovacs, Xiaoyan Mo, Nikolaos Vasilakis, Sangeeta Bhargava, Timothy Zamb, Stephen Udem
  • Induction of mucosal immunity by vaccination via the skin route
    Publication number: 20060228375
    Abstract: Methods for generating an immune response at a mucosal surface are described. Compositions suitable for use in the methods for generating an immune response at a mucosal surface are also described. In addition, methods for treating or preventing a disease caused by the entry of a pathogen into the body of a subject via a mucosal surface are provided.
    Type: Application
    Filed: June 16, 2006
    Publication date: October 12, 2006
    Inventors: Dexiang Chen, Sangeeta Bhargava, Deborah Fuller
  • Induction of mucosal immunity by vaccination via the skin route
    Publication number: 20040109874
    Abstract: Methods for generating an immune response at a mucosal surface are described. Compositions suitable for use in the methods for generating an immune response at a mucosal surface are also described. In addition, methods for treating or preventing a disease caused by the entry of a pathogen into the body of a subject via a mucosal surface are provided.
    Type: Application
    Filed: December 2, 2003
    Publication date: June 10, 2004
    Applicant: PowderJect Vaccines, Inc.
    Inventors: Dexiang Chen, Sangeeta Bhargava, Deborah Fuller