Abstract: The present invention provides a pharmaceutical composition for prevention or treatment of a stress disease and depression, the pharmaceutical composition be safely useable without toxicity and side effects by using an extract of leaves of Vaccinium bracteatum Thunb., which is natural resource of Korea, so that the reduction of manufacturing and production costs and the import substitution and export effects can be expected through the replacement of a raw material for preparation with a plant inhabiting in nature.

Abstract: Provided is pyrazole derivatives as a TNIK (Traf2- and NCK-interacting kinase), IKK? (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor; the pyrazole derivative according to the present invention effectively inhibits TNIK, IKK? and TBK1, and thus is useful not only as an anticancer agent for the treatment of various cancers including colorectal cancer, breast cancer, CNS cancer, colon cancer, non-small cell lung cancer, kidney cancer, prostate cancer, ovarian cancer, uterus cancer, stomach cancer, liver cancer, skin cancer, lung cancer, brain cancer, bladder cancer, esophageal cancer, pancreatic cancer, thyroid cancer, head and neck cancer, squamous cell carcinoma, osteosarcoma, B-cell or T-cell lymphoma, acute or chronic leukemia and multiple myeloma, but as a therapeutic agent for chronic inflammation.

Abstract: Provided are 7-azaindole or 4,7-diazaindole derivatives as an IKK? (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor. The 7-azaindole or 4,7-diazaindole derivative effectively inhibits IKK? and TBK1, and thus is useful not only as an anticancer agent for the treatment of various cancers including colorectal cancer, breast cancer, CNS cancer, colon cancer, non-small cell lung cancer, kidney cancer, prostate cancer, ovarian cancer, uterus cancer, stomach cancer, liver cancer, skin cancer, lung cancer, brain cancer, bladder cancer, esophageal cancer, pancreatic cancer, thyroid cancer, head and neck cancer, squamous cell carcinoma, osteosarcoma, B-cell or T-cell lymphoma, acute or chronic leukemia and multiple myeloma, but as a therapeutic agent for chronic inflammation.

Abstract: The present invention relates to a method for using a combination of two kinds of thermal stabilizers in a production process in order to improve the thermal stability of biodegradable polyester resins, and to biodegradable polyester resin produced therefrom. In said method, two kinds of thermal stabilizers improve thermal stability by acting complementarily with each other. Thus, a high temperature reaction is possible, and due to an increase in the reactivity, the reaction time is shortened and the molecular weight is increased. In addition, the obtained resin can provide high quality products, since the acid value thereof is reduced to improve the hydrolysis resistance thereof, and the chromaticity thereof is enhanced to thereby be capable of preventing a yellowing phenomenon of the final product.

Abstract: The present invention relates to a biodegradable resin having outstanding colouring properties, and provides a resin composition which does not give rise to problems such as reduced strength due to colouration. The composition of the present invention, suggests that a PBSAT resin is used as a biodegradable resin, and colouration is performed with same. Also, at this time, the colourant can be mixed in the form of masterbatch. In the present invention, the resin composition is used in the production of various products, in particular monofilament yarn produced via spinning and a fishing net manufactured from same is provided. Fishing nets such as the above are advantageous in that such fishing nets can be realized in various colours in accordance with customer requirements and satisfy the required strength and, after use, degrade naturally in seawater and so do not give rise to problems like environmental pollution.

Abstract: The present invention is characterized by introducing isosorbide to a monomer configuration for securing the transparency of a biodegradable polymer as well as providing material having excellent heat resistance and flexibility, As a monomer, a component derived from isosorbide which has a rigid structure is contained by 10-50 mol % of a total diol component, thereby bringing a heat resistance enhancing effect, and enhancing transparency by interfering with crystal formation, and allowing for providing a polymer having excellent flexibility. Thus, the present invention may enable securing stability in usage especially in the packaging area, and enable the heightening of the range of usage and utilization thereof.

Abstract: Provided are 7-azaindole or 4,7-diazaindole derivatives as an IKK? (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor. The 7-azaindole or 4,7-diazaindole derivative effectively inhibits IKK? and TBK1, and thus is useful not only as an anticancer agent for the treatment of various cancers including colorectal cancer, breast cancer, CNS cancer, colon cancer, non-small cell lung cancer, kidney cancer, prostate cancer, ovarian cancer, uterus cancer, stomach cancer, liver cancer, skin cancer, lung cancer, brain cancer, bladder cancer, esophageal cancer, pancreatic cancer, thyroid cancer, head and neck cancer, squamous cell carcinoma, osteosarcoma, B-cell or T-cell lymphoma, acute or chronic leukemia and multiple myeloma, but as a therapeutic agent for chronic inflammation.

Abstract: Provided is pyrazole derivatives as a TNIK (Traf2- and NCK-interacting kinase), IKK? (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor; the pyrazole derivative according to the present invention effectively inhibits TNIK, IKK? and TBK1, and thus is useful not only as an anticancer agent for the treatment of various cancers including colorectal cancer, breast cancer, CNS cancer, colon cancer, non-small cell lung cancer, kidney cancer, prostate cancer, ovarian cancer, uterus cancer, stomach cancer, liver cancer, skin cancer, lung cancer, brain cancer, bladder cancer, esophageal cancer, pancreatic cancer, thyroid cancer, head and neck cancer, squamous cell carcinoma, osteosarcoma, B-cell or T-cell lymphoma, acute or chronic leukemia and multiple myeloma, but as a therapeutic agent for chronic inflammation.

Abstract: A biodegradable polyester resin and an article including the same are provided. The biodegradable polyester resin includes a diol residue (DO) that includes a cycloaliphatic diol residue (A) and an aliphatic diol residue (B); and a dicarboxylic acid residue (DC) that includes at least one of an aromatic dicarboxylic acid residue (C), an aliphatic dicarboxylic acid residue (D), and a cycloaliphatic dicarboxylic acid residue (E). Thus, the biodegradable polyester resin may have an excellent transparency and flexibility.

Abstract: There is provided a method of preparation for a biodegradable co-polyester resin with improved hydrolysis resistance, the method including performing a primary esterification reaction between an aliphatic dihydroxy compound and an aliphatic dicarboxylic acid compound, and performing a secondary transesterification reaction with addition of an aromatic dicarboxylate after the primary esterification reaction, in which a short chain alcohol-type branching agent is added to the primary esterification reaction or to the secondary transesterification reaction.

Abstract: Methods of preparing an aromatic liquid crystalline polyester resin and an aromatic liquid crystalline polyester resin compound are disclosed. A method of preparing an aromatic liquid crystalline polyester resin may include: acetylating a first monomer including an amino group by a reaction with a carboxylic acid anhydride; acetylating a second monomer including a hydroxyl group and not including an amino acid group with an additional carboxylic acid anhydride; and synthesizing an aromatic liquid crystalline polyester prepolymer by a condensation polymerization reaction of the acetylated first and second monomers with dicarboxylic acid. A method of preparing an aromatic liquid crystalline polyester resin compound may use the aromatic liquid crystalline polyester resin prepared according to the forgoing method.

Abstract: A method of preparing a wholly aromatic liquid crystalline polyester amide resin and a method of preparing a wholly aromatic liquid crystalline polyester amide resin compound. The method of preparing a wholly aromatic liquid crystalline polyester amide resin is performed using a monomer having both a hydroxyl group and an acetylamino group or using a monomer having a hydroxyl group and a monomer having an acetylamino group. In addition, the method of preparing a wholly aromatic liquid crystalline polyester amide resin compound is performed using a wholly aromatic liquid crystalline polyester amide resin that is prepared using the method.

Abstract: A prism sheet, a backlight unit, and a liquid crystal display device, the prism sheet including a transparent substrate; and at least one prism on the transparent substrate, wherein a refractive index (n) and a basic angle (?) of the at least one prism satisfies the following condition: 1?n/sin ??4.

Abstract: A method of preparing a wholly aromatic liquid crystalline polyester amide resin and a method of preparing a wholly aromatic liquid crystalline polyester amide resin compound. The method of preparing a wholly aromatic liquid crystalline polyester amide resin is performed using a monomer having both a hydroxyl group and an acetylamino group or using a monomer having a hydroxyl group and a monomer having an acetylamino group. In addition, the method of preparing a wholly aromatic liquid crystalline polyester amide resin compound is performed using a wholly aromatic liquid crystalline polyester amide resin that is prepared using the method.

Abstract: Methods of preparing an aromatic liquid crystalline polyester resin and an aromatic liquid crystalline polyester resin compound are disclosed. A method of preparing an aromatic liquid crystalline polyester resin may include: acetylating a first monomer including an amino group by a reaction with a carboxylic acid anhydride; acetylating a second monomer including a hydroxyl group and not including an amino acid group with an additional carboxylic acid anhydride; and synthesizing an aromatic liquid crystalline polyester prepolymer by a condensation polymerization reaction of the acetylated first and second monomers with dicarboxylic acid. A method of preparing an aromatic liquid crystalline polyester resin compound may use the aromatic liquid crystalline polyester resin prepared according to the forgoing method.

Abstract: A prism sheet, a backlight unit, and a liquid crystal display device, the prism sheet including a transparent substrate; and at least one prism on the transparent substrate, wherein a refractive index (n) and a basic angle (?) of the at least one prism satisfies the following condition: 1?n/sin ??4.