Patents by Inventor Sanjay D'Souza

Sanjay D'Souza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATING LIPOPROTEIN-RELATED DISEASES
    Publication number: 20230293646
    Abstract: The present disclosure relates to methods, compositions and kits for modulating the expression of LPA gene and for treating lipoprotein-related diseases, for example cardiovascular diseases, in a subject by gene editing.
    Type: Application
    Filed: March 20, 2023
    Publication date: September 21, 2023
    Inventors: Sanjay D'Souza, Laura Serwer, Jonathan Terrett, John Kulman
  • COMPOSITIONS AND METHODS FOR EDITING BETA-GLOBIN FOR TREATMENT OF HEMAGLOBINOPATHIES
    Publication number: 20230022146
    Abstract: The disclosure features methods of correcting a mutation in the human beta-globin (HBB) gene in a cell or population of cells. The disclosure also features methods of increasing repair of a DNA double stranded break (DSB) in an HBB gene by the homology-directed repair (HDR) pathway. The disclosure also features compositions for use in the methods.
    Type: Application
    Filed: June 17, 2020
    Publication date: January 26, 2023
    Inventors: Sanjay D'SOUZA, Jason WEST, Brenda K. EUSTACE, Sudipta MAHAJAN
  • COMPOSITIONS AND METHODS FOR EDITING BETA-GLOBIN FOR TREATMENT OF HEMAGLOBINOPATHIES
    Publication number: 20220228142
    Abstract: The disclosure features systems and methods for correcting a mutation in the human beta-globin (HBB) gene in a cell or population of cells. The disclosure also features methods of increasing repair of a DNA double stranded break (DSB) in an HBB gene by the homology-directed repair (HDR) pathway. The disclosure also features compositions for use in the methods.
    Type: Application
    Filed: December 17, 2021
    Publication date: July 21, 2022
    Inventors: Sanjay D'SOUZA, Jason WEST, Brenda K. EUSTACE, Sudipta MAHAJAN
  • METHODS AND COMPOSITIONS FOR IMPROVED HOMOLOGY DIRECTED REPAIR
    Publication number: 20210008161
    Abstract: The disclosure features methods of increasing repair of a DNA double stranded break (DSB) in a target gene by the homology-directed repair (HDR) pathway. The disclosure also features compositions for use in the methods.
    Type: Application
    Filed: June 17, 2020
    Publication date: January 14, 2021
    Inventors: Sanjay D'Souza, Jason West