Patents by Inventor Sanjay Desai
Sanjay Desai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11835928Abstract: Real-time dynamic process modeling in an online model-based process control computing environment. A solver system utilizes an oracle to implement adaptive algorithms for a mixed integer nonlinear programming (MINLP) solver and a nonlinear programming (NLP) solver.Type: GrantFiled: January 25, 2021Date of Patent: December 5, 2023Assignee: AVEVA SOFTWARE, LLCInventors: Rajkumar Vedam, Detong Zhang, Purt Tanartkit, Gareth Hillier, Sanjay Desai, John C. Hernandez
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Publication number: 20230346797Abstract: Disclosed are inhibitors of the plasmodial surface anion channel (PSAC) inhibitors and the use thereof in treating or preventing malaria in an animal such as a human, comprising administering an effective amount of an inhibitor or a combination of inhibitors. An example of such an inhibitor is a compound of formula I, or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein.Type: ApplicationFiled: July 10, 2023Publication date: November 2, 2023Applicant: The United States of America,as represented by the Secretary,Department of Health and Human ServicesInventors: Sanjay A. Desai, Ajay D. Pillai
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Publication number: 20210247726Abstract: Real-time dynamic process modeling in an online model-based process control computing environment. A solver system utilizes an oracle to implement adaptive algorithms for a mixed integer nonlinear programming (MINLP) solver and a nonlinear programming (NLP) solver.Type: ApplicationFiled: January 25, 2021Publication date: August 12, 2021Inventors: Rajkumar Vedam, Detong Zhang, Purt Tanartkit, Gareth Hillier, Sanjay Desai, John C. Hernandez
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Publication number: 20210121476Abstract: Disclosed are inhibitors of the plasmodial surface anion channel (PSAC) inhibitors and the use thereof in treating or preventing malaria in an animal such as a human, comprising administering an effective amount of an inhibitor or a combination of inhibitors. An example of such an inhibitor is a compound of formula I, or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein.Type: ApplicationFiled: January 4, 2021Publication date: April 29, 2021Applicant: The United States of America,as represented by the Secretary,Department of Health and Human ServicesInventors: Sanjay A. Desai, Ajay D. Pillai
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Publication number: 20210085679Abstract: The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula I: Q-Y—R1—R2??(I), wherein Q, Y, R1, and R2 are as described herein. Methods of inhibiting a plasmodial surface anion channel of a parasite in an animal are also provided. The invention also provides pharmaceutical compositions comprising a compound represented by formula I in combination with any one or more compounds represented by formulas II, V, and VI. Use of the pharmaceutical compositions for treating or preventing malaria or for inhibiting a plasmodial surface anion channel in animals including humans are also provided. Also provided by the invention are clag3 amino acid sequences and related nucleic acids, vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions.Type: ApplicationFiled: December 8, 2020Publication date: March 25, 2021Applicant: The United States of America,as represented by the Secretary,Department of Health and Human ServicesInventor: Sanjay A. Desai
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Patent number: 10908563Abstract: Real-time dynamic process modeling in an online model-based process control computing environment. A solver system utilizes an oracle to implement adaptive algorithms for a mixed integer nonlinear programming (MINLP) solver and a nonlinear programming (NLP) solver.Type: GrantFiled: November 27, 2018Date of Patent: February 2, 2021Assignee: AVEVA SOFTWARE, LLCInventors: Rajkumar Vedam, Detong Zhang, Purt Tanartkit, Gareth Hillier, Sanjay Desai, John C. Hernandez
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Patent number: 10881669Abstract: Disclosed are inhibitors of the plasmodial surface anion channel (PSAC) inhibitors and the use thereof in treating or preventing malaria in an animal such as a human, comprising administering an effective amount of an inhibitor or a combination of inhibitors. An example of such an inhibitor is a compound of formula I, or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein.Type: GrantFiled: May 21, 2018Date of Patent: January 5, 2021Assignee: The United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Sanjay A. Desai, Ajay D. Pillai
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Patent number: 10869865Abstract: The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula I: Q-Y—R1—R2??(I), wherein Q, Y, R1, and R2 are as described herein. Methods of inhibiting a plasmodial surface anion channel of a parasite in an animal are also provided. The invention also provides pharmaceutical compositions comprising a compound represented by formula I in combination with any one or more compounds represented by formulas II, V, and VI. Use of the pharmaceutical compositions for treating or preventing malaria or for inhibiting a plasmodial surface anion channel in animals including humans are also provided. Also provided by the invention are clag3 amino acid sequences and related nucleic acids, vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions.Type: GrantFiled: March 5, 2019Date of Patent: December 22, 2020Assignee: The United States of America, as represented by the Secretary, Department of Health and Human ServInventor: Sanjay A. Desai
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Publication number: 20190332070Abstract: Real-time dynamic process modeling in an online model-based process control computing environment. A solver system utilizes an oracle to implement adaptive algorithms for a mixed integer nonlinear programming (MINLP) solver and a nonlinear programming (NLP) solver.Type: ApplicationFiled: November 27, 2018Publication date: October 31, 2019Inventors: Rajkumar Vedam, Detong Zhang, Purt Tanartkit, Gareth Hillier, Sanjay Desai, John C. Hernandez
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Publication number: 20190183889Abstract: The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula I: Q-Y—R1—R2??(I), wherein Q, Y, R1, and R2 are as described herein. Methods of inhibiting a plasmodial surface anion channel of a parasite in an animal are also provided. The invention also provides pharmaceutical compositions comprising a compound represented by formula I in combination with any one or more compounds represented by formulas II, V, and VI. Use of the pharmaceutical compositions for treating or preventing malaria or for inhibiting a plasmodial surface anion channel in animals including humans are also provided. Also provided by the invention are clag3 amino acid sequences and related nucleic acids, vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions.Type: ApplicationFiled: March 5, 2019Publication date: June 20, 2019Applicant: The United States of America, as represented by the Secretary, Department of Health and Human ServInventor: Sanjay A. Desai
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Patent number: 10265313Abstract: The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula I: Q-Y—R1—R2??(I), wherein Q, Y, R1, and R2 are as described herein. Methods of inhibiting a plasmodial surface anion channel of a parasite in an animal are also provided. The invention also provides pharmaceutical compositions comprising a compound represented by formula I in combination with any one or more compounds represented by formulas II, V, and VI. Use of the pharmaceutical compositions for treating or preventing malaria or for inhibiting a plasmodial surface anion channel in animals including humans are also provided. Also provided by the invention are clag3 amino acid sequences and related nucleic acids, vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions.Type: GrantFiled: October 3, 2017Date of Patent: April 23, 2019Assignee: The United States of America, as represented by the Secretary, Department of Health and Human ServicesInventor: Sanjay A. Desai
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Patent number: 10152036Abstract: Real-time dynamic process modeling in an online model-based process control computing environment. A solver system utilizes an oracle to implement adaptive algorithms for a mixed integer nonlinear programming (MINLP) solver and a nonlinear programming (NLP) solver.Type: GrantFiled: December 30, 2015Date of Patent: December 11, 2018Assignee: Schneider Electric Software, LLCInventors: Rajkumar Vedam, Detong Zhang, Purt Tanartkit, Gareth Hillier, Sanjay Desai, John C. Hernandez
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Publication number: 20180264003Abstract: Disclosed are inhibitors of the plasmodial surface anion channel (PSAC) inhibitors and the use thereof in treating or preventing malaria in an animal such as a human, comprising administering an effective amount of an inhibitor or a combination of inhibitors. An example of such an inhibitor is a compound of formula I, or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein.Type: ApplicationFiled: May 21, 2018Publication date: September 20, 2018Applicant: The United States of America, as represented by the Secretary, Department of Health and HumanInventors: Sanjay A. Desai, Ajay D. Pillai
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Patent number: 9974796Abstract: Disclosed are inhibitors of the plasmodial surface anion channel (PSAC) inhibitors and the use thereof in treating or preventing malaria in an animal such as a human, comprising administering an effective amount of an inhibitor or a combination of inhibitors. An example of such an inhibitor is a compound of formula I, or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein.Type: GrantFiled: July 18, 2016Date of Patent: May 22, 2018Assignee: The United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Sanjay A. Desai, Ajay D. Pillai
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Patent number: 9885644Abstract: The present invention generally relates to a method for determining the dynamic viscoelastic properties of cells, more particularly to a method for rapidly determining the dynamic viscoelastic properties of healthy and unhealthy cells by determining the phase shift be the application of a modulating force to the cells and the cells' response to the modulating force.Type: GrantFiled: June 17, 2014Date of Patent: February 6, 2018Assignees: Colorado School of Mines, National Institute of Health, University of MarylandInventors: Tobias Sawetzki, David W. M. Marr, Charles Eggleton, Sanjay Desai
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Publication number: 20180015086Abstract: The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula I: Q—Y—R1—R2??(I), wherein Q, Y, R1, and R2 are as described herein. Methods of inhibiting a plasmodial surface anion channel of a parasite in an animal are also provided. The invention also provides pharmaceutical compositions comprising a compound represented by formula I in combination with any one or more compounds represented by formulas II, V, and VI. Use of the pharmaceutical compositions for treating or preventing malaria or for inhibiting a plasmodial surface anion channel in animals including humans are also provided. Also provided by the invention are clag3 amino acid sequences and related nucleic acids, vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions.Type: ApplicationFiled: October 3, 2017Publication date: January 18, 2018Applicant: The United States of America, as represented by the Secretary, Department of Health and Human ServInventor: Sanjay A. Desai
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Patent number: 9808458Abstract: The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula I: Q-Y—R1—R2??(I), wherein Q, Y, R1, and R2 are as described herein. Methods of inhibiting a plasmodial surface anion channel of a parasite in an animal are also provided. The invention also provides pharmaceutical compositions comprising a compound represented by formula I in combination with any one or more compounds represented by formulas II, V, and VI. Use of the pharmaceutical compositions for treating or preventing malaria or for inhibiting a plasmodial surface anion channel in animals including humans are also provided. Also provided by the invention are clag3 amino acid sequences and related nucleic acids, vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions.Type: GrantFiled: March 17, 2016Date of Patent: November 7, 2017Assignee: The United States of America, as represented by the Secretary, Department of Health and Human ServicesInventor: Sanjay A. Desai
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Publication number: 20170192397Abstract: Real-time dynamic process modeling in an online model-based process control computing environment. A solver system utilizes an oracle to implement adaptive algorithms for a mixed integer nonlinear programming (MINLP) solver and a nonlinear programming (NLP) solver.Type: ApplicationFiled: December 30, 2015Publication date: July 6, 2017Applicant: Invensys Systems, Inc.Inventors: Rajkumar Vedam, Detong Zhang, Purt Tanartkit, Gareth Hillier, Sanjay Desai, John C. Hernandez
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Publication number: 20160324866Abstract: Disclosed are inhibitors of the plasmodial surface anion channel (PSAC) inhibitors and the use thereof in treating or preventing malaria in an animal such as a human, comprising administering an effective amount of an inhibitor or a combination of inhibitors. An example of such an inhibitor is a compound of formula I, or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein.Type: ApplicationFiled: July 18, 2016Publication date: November 10, 2016Inventors: Sanjay A. Desai, Ajay D. Pillai
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Patent number: 9394316Abstract: Disclosed are inhibitors of the plasmodial surface anion channel (PSAC) inhibitors and the use thereof in treating or preventing malaria in an animal such as a human, comprising administering an effective amount of an inhibitor or a combination of inhibitors. An example of such an inhibitor is a compound of formula I, or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein.Type: GrantFiled: December 3, 2013Date of Patent: July 19, 2016Assignee: The United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Sanjay A. Desai, Ajay D. Pillai