Abstract: A magnetic necklace jewelry 100 having various design configurations is provided herein. a first component 102 embedded with multiple magnets 112 which is divided into part A and part B, characterized in that the magnets being embedded within inside portion 116 of the first component such that to attach or detach, part A from part B; a second component 104 consisting of mechanically interconnected metal elements forming a chain which is connected to either side of the first component thereby forming a necklace like jewelry article; Wherein said first component 102 when magnetically detached or free, forms a single larger circumference loop (106) having length in the range between 15 to 25 inches, wherein the first component when magnetically attached to each other, forms a multiple circumference loop, thereby enabling a person to change wearing style of the necklace jewelry instantly.

Abstract: A pivot chain end for a jewelry is provided in the present embodiment. The pivot chain end has a 360 degree linking mechanism for chains having jewelry items which helps in arresting the improper fall issue of the necklace when worn by a wearer. The pivot chain end includes an eyelet which is circular in shape linked with a back chain having an abutted cylindrical portion with a through hole and a metal disc having three flat flanks and one curved ridged side, wherein the metal disc allows the screw to pass through within the disc and connect the eyelet, through a partially threaded body on the screw, thereby securing the metal disc with the eyelet and enabling the eyelet to freely rotate 360 degree axially as per movement of the back chain.

Abstract: A magnetic bangle jewelry 100 having various design configurations is provided herein. The bangle includes a robust circular shaped hollow structure 104 which is separable into two magnetically detachable parts, Part A and Part B, wherein Part A and Part B consist of flat portions 110, 114 on one side, and varied design structure 112, 116 on other side; and an array of geometrically shaped magnets 106, 108, spaced apart from each other is embedded within the flat portions 110, 114 of part A and part B respectively, wherein the magnets enable attaching and detaching of part A with Part B in different combinations, thereby resulting into varied design configurations a-e of the bangle jewelry.

Abstract: A pivot chain end for a jewelry is provided in the present embodiment. The pivot chain end has a 360 degree linking mechanism for chains having jewelry items which helps in arresting the improper fall issue of the necklace when worn by a wearer. The pivot chain end includes an O ring which is circular in shape linked with a back chain having an abutted cylindrical portion with a through hole and a metal disc having three flat flanks and one curved ridged side, wherein the metal disc allows the screw to pass through within the disc and connect the O ring, through a partially threaded body on the screw, thereby securing the metal disc with the O ring and enabling the O ring to freely rotate 360 degree axially as per movement of the back chain.

Abstract: The present disclosure relates to solid state forms of Acalabrutinib, processes for the preparation thereof and pharmaceutical compositions comprising said solid state forms of Acalabrutinib.

Abstract: The present invention relates to an improved and industrial friendly process for lactonization to produce compound of the Formula [I], from compound of the Formula [II] in presence of an inorganic compound as a suitable lactonizing agent, preferably alkali metal hydrogen sulfate, and crystallizing the obtained lactone product in a solvent; or treating compound of the Formula [II] in the presence of an inorganic compound preferably alkali metal hydrogen sulfate using phase transfer catalyst in heterogeneous phase followed by crystallizing the obtained lactone product in a solvent.

Abstract: The present invention relates to an improved and industrial friendly process for lactonization to produce compound of the Formula [I], from compound of the Formula [II] in presence of an inorganic compound as a suitable lactonizing agent, preferably alkali metal hydrogen sulfate, and crystallizing the obtained lactone product in a solvent; or treating compound of the Formula [II] in the presence of an inorganic compound preferably alkali metal hydrogen sulfate using phase transfer catalyst in heterogeneous phase followed by crystallizing the obtained lactone product in a solvent.