Patents by Inventor Sanjay Kaul

Sanjay Kaul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prevention and treatment of restenosis by local administration of drug
    Patent number: 8119590
    Abstract: Apolipoprotein A-I (ApoA-I), preferably a variant form such as Apolipoprotein A-I Milano (ApoA-IM), alone or more preferably in combination with a lipid carrier such as phospholipids or other drug, can be administered locally before or during bypass surgery on diseased coronary, peripheral, and cerebral arteries, surgery to implant grafts or transplanted organs, or angioplasty, or to stabilize unstable plaques. In an alternative embodiment, the apolipoprotein is not provided directly, but the gene encoding the apolipoprotein is provided. The gene is introduced into the blood vessel in a manner similar to that used for the protein, where the protein is then expressed. The technique can also be used for delivery of genes for treatment or prevention or restenosis or other cardiovascular diseases.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: February 21, 2012
    Assignees: Cedars-Sinai Medical Center, Esperion Therapeutics, Inc
    Inventors: Charles L. Bisgaier, Prediman Krishan Shah, Sanjay Kaul
  • Stent coated with magnesium-based compound for reducing thrombosis
    Patent number: 7452373
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: November 18, 2008
    Assignee: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah
  • Method of reducing thrombosis and complications after arterial angioplasty using stent coated with magnesium-based compound
    Patent number: 7279183
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: October 9, 2007
    Assignee: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah
  • Instrument coated with magnesium-based compound for reducing thrombosis
    Publication number: 20040247642
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Application
    Filed: December 24, 2003
    Publication date: December 9, 2004
    Applicant: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah
  • Method of inhibiting thrombosis and complications after angioplasty using magnesium-based compound
    Publication number: 20040146586
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Application
    Filed: December 24, 2003
    Publication date: July 29, 2004
    Applicant: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah
  • Method of reducing thrombosis and complications after arterial angioplasty using stent coated with magnesium-based compound
    Publication number: 20040138739
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Application
    Filed: December 24, 2003
    Publication date: July 15, 2004
    Applicant: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah
  • Prevention of in-stent thrombosis and complications after arterial angioplasty with stent placement using magnesium
    Patent number: 6692772
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: February 17, 2004
    Assignee: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah
  • Prevention and treatment of restenosis by local administration of drug
    Publication number: 20030109442
    Abstract: Apolipoprotein A-I (ApoA-I), preferably a variant form such as Apolipoprotein A-I Milano (ApoA-IM), alone or more preferably in combination with a lipid carrier such as phospholipids or other drug, can be administered locally before or during bypass surgery on diseased coronary, peripheral, and cerebral arteries, surgery to implant grafts or transplanted organs, or angioplasty, or to stabilize unstable plaques. In an alternative embodiment, the apolipoprotein is not provided directly, but the gene encoding the apolipoprotein is provided. The gene is introduced into the blood vessel in a manner similar to that used for the protein, where the protein is then expressed. The technique can also be used for delivery of genes for treatment or prevention or restenosis or other cardiovascular diseases.
    Type: Application
    Filed: September 27, 2002
    Publication date: June 12, 2003
    Applicants: Esperion Therapeutics, Inc., Cedars-Sinai Medical Center
    Inventors: Charles L. Bisgaier, Prediman Krishan Shah, Sanjay Kaul
  • Prevention of in-stent thrombosis and complications after arterial angioplasty with stent placement using magnesium
    Publication number: 20030017188
    Abstract: Treatment with magnesium produces a inhibition of acute stent thrombosis under high-shear flow conditions without any hemostatic or significant hemodynamic complications.
    Type: Application
    Filed: July 18, 2001
    Publication date: January 23, 2003
    Applicant: Cedars-Sinai Medical Center
    Inventors: Sanjay Kaul, Prediman K. Shah