Patents by Inventor Sanjay Konagurthu
Sanjay Konagurthu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11839689Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.Type: GrantFiled: November 11, 2022Date of Patent: December 12, 2023Assignees: Astellas Pharma Inc., Medivation Prostate Therapeutics LLCInventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
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Publication number: 20230210778Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.Type: ApplicationFiled: November 11, 2022Publication date: July 6, 2023Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
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Publication number: 20230122911Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.Type: ApplicationFiled: November 11, 2022Publication date: April 20, 2023Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
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Publication number: 20220241208Abstract: The present disclosure provides, in part, pharmaceutical compositions that comprise a spray dried dispersion which contains the disclosed compound, and optionally, pharmaceutical excipients. The pharmaceutical compositions of the disclosure may be used in the treatment of Hepatitis B (HBV).Type: ApplicationFiled: May 22, 2020Publication date: August 4, 2022Inventors: Lee D. ARNOLD, George Koan WONG, Kirk HENNE, James Francis HULVAT, Sanjay KONAGURTHU, Ian Scott MCINTOSH, Matthew David WESSEL, Thomas REYNOLDS, Richard J. COLONNO, Uri A. LOPATIN
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Patent number: 11116728Abstract: A pharmaceutical composition comprises multiparticulates comprising a melt-congeal core and a solid amorphous dispersion layer of a poorly water soluble drug and polymer. The multiparticulates are suitable for improving bioavailability of poorly water soluble drugs. The melt-congeal cores facilitate application of the solid amorphous dispersion layer, and allow incorporation of additional optional components to the core so as to adjust the release of drug from the multiparticulate.Type: GrantFiled: June 13, 2019Date of Patent: September 14, 2021Assignee: Bend Research, Inc.Inventors: Dwayne Thomas Friesen, Leah E. Appel, Joshua Richard Shockey, Sanjay Konagurthu, Edward Dennis LaChapelle
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Publication number: 20200060976Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.Type: ApplicationFiled: April 1, 2019Publication date: February 27, 2020Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
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Publication number: 20190307702Abstract: A pharmaceutical composition comprises multiparticulates comprising a melt-congeal core and a solid amorphous dispersion layer of a poorly water soluble drug and polymer. The multiparticulates are suitable for improving bioavailability of poorly water soluble drugs. The melt-congeal cores facilitate application of the solid amorphous dispersion layer, and allow incorporation of additional optional components to the core so as to adjust the release of drug from the multiparticulate.Type: ApplicationFiled: June 13, 2019Publication date: October 10, 2019Applicant: Bend Research, Inc.Inventors: Dwayne Thomas Friesen, Leah E. Appel, Joshua Richard Shockey, Sanjay Konagurthu, Edward Dennis LaChapelle
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Patent number: 10357462Abstract: A pharmaceutical composition comprises multiparticulates comprising a melt-congeal core and a solid amorphous dispersion layer of a poorly water soluble drug and polymer. The multiparticulates are suitable for improving bioavailability of poorly water soluble drugs. The melt-congeal cores facilitate application of the solid amorphous dispersion layer, and allow incorporation of additional optional components to the core so as to adjust the release of drug from the multiparticulate.Type: GrantFiled: November 19, 2007Date of Patent: July 23, 2019Assignee: Ben Research, Inc.Inventors: Dwayne Thomas Friesen, Leah E. Appel, Joshua Richard Shockey, Sanjay Konagurthu, Edward Dennis LaChapelle
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Publication number: 20190209476Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.Type: ApplicationFiled: July 24, 2018Publication date: July 11, 2019Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
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Publication number: 20180344646Abstract: Amorphous dispersion granules comprising an amorphous solid solution of an active pharmaceutical ingredient and a dispersing polymer, and deposited thereon a substrate comprising at least one first tableting agent, as well as oral dosage forms comprising the amorphous dispersion granules of the invention, including pharmaceutically acceptable tablets comprising the amorphous dispersion granules of the invention, and methods of preparing amorphous dispersion granules and pharmaceutically acceptable tablets manufactured therefrom.Type: ApplicationFiled: November 14, 2016Publication date: December 6, 2018Applicant: PATHEON DEVELOPMENT SERVICES INC.Inventors: Sanjay Konagurthu, Thomas REYNOLDS, Marshall CREW
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Publication number: 20170224624Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.Type: ApplicationFiled: September 16, 2016Publication date: August 10, 2017Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
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Patent number: 9713594Abstract: An exemplary method comprises providing a spray-dried dispersion comprising particles, the particles comprising an active agent and a polymer, the dispersion particles having an average particle diameter of less than 50 ?m. An ordered mixture is formed by high-shear mixing the dispersion with a powdered glidant, wherein the average particle diameter of the glidant is less than or equal to one fifth the average particle diameter of the dispersion after high-shear mixing. The dosage forms are formed by at least one of directly compressing the ordered mixture to form a tablet and encapsulating the ordered mixture to form a capsule.Type: GrantFiled: September 5, 2013Date of Patent: July 25, 2017Assignee: Bend Research, Inc.Inventors: Jason A. Everett, Randy J. Wald, Sanjay Konagurthu
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Publication number: 20170027910Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.Type: ApplicationFiled: February 8, 2016Publication date: February 2, 2017Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
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Publication number: 20150216813Abstract: An exemplary method comprises providing a spray-dried dispersion comprising particles, the particles comprising an active agent and a polymer, the dispersion particles having an average particle diameter of less than 50 ?m. An ordered mixture is formed by high-shear mixing the dispersion with a powdered glidant, wherein the average particle diameter of the glidant is less than or equal to one fifth the average particle diameter of the dispersion after high-shear mixing. The dosage forms are formed by at least one of directly compressing the ordered mixture to form a tablet and encapsulating the ordered mixture to form a capsule.Type: ApplicationFiled: September 5, 2013Publication date: August 6, 2015Applicant: Bend Research, Inc.Inventors: Jason A. Everett, Randy J. Wald, Sanjay Konagurthu
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Publication number: 20140378517Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.Type: ApplicationFiled: September 10, 2014Publication date: December 25, 2014Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
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Publication number: 20140179749Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.Type: ApplicationFiled: September 11, 2013Publication date: June 26, 2014Applicants: BEND RESEARCH, ASTELLAS PHARMA INC., MEDIVATION PROSTATE THERAPEUTICS, INC.Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
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Publication number: 20140100256Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.Type: ApplicationFiled: September 11, 2013Publication date: April 10, 2014Applicants: BEND RESEARCH, ASTELLAS PHARMA INC., MEDIVATION PROSTATE THERAPEUTICS, INC.Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
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Patent number: 8236349Abstract: A pharmaceutical composition comprises multiparticulates comprising a drug, a matrix material, and swelling agent. In one aspect, the multiparticulates comprise a core comprising a drug, and a coating surrounding the core. The coating is selected from the group consisting of (i) a water-permeable, substantially drug-impermeable coating, and (ii) an anti-enteric coating.Type: GrantFiled: April 6, 2005Date of Patent: August 7, 2012Assignee: Bend Research Inc.Inventors: Leah Elizabeth Appel, Dwayne Thomas Friesen, Edward Dennis LaChapelle, Sanjay Konagurthu, Richard Frank Falk, Joseph P. Reo
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Publication number: 20080138428Abstract: A highly porous, fast-disintegrating binder suitable for pharmaceutical applications and methods of making the same are disclosed, the binder comprising microporous particles of an aqueous-soluble cellulosic polymer and a wicking agent. Pharmaceutical compositions and fast-disintegrating dosage forms containing the binder are also disclosed.Type: ApplicationFiled: January 17, 2006Publication date: June 12, 2008Inventors: Roderick Jack Ray, Dwayne Thomas Friesen, Marshall David Crew, Richard Frank Falk, Sanjay Konagurthu
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Publication number: 20070196483Abstract: A pharmaceutical composition comprises multiparticulates comprising a drug, a matrix material, and swelling agent. In one aspect, the multiparticulates comprise a core comprising a drug, and a coating surrounding the core. The coating is selected from the group consisting of (i) a water-permeable, substantially drug-impermeable coating, and (ii) an anti-enteric coating.Type: ApplicationFiled: April 6, 2005Publication date: August 23, 2007Inventors: Leah Appel, Dwayne Friesen, Edward Lachapelle, Sanjay Konagurthu, Richard Falk, Joseph Reo