Patents by Inventor Sanjay R. Chemburkar

Sanjay R. Chemburkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHENYLALKYL N-HYDROXYUREAS FOR TREATING LEUKOTRIENE RELATED PATHOLOGIES
    Publication number: 20130317078
    Abstract: The method of treating patients by administering N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea for treatment of leukotriene related pathologies, and compositions for this use.
    Type: Application
    Filed: June 20, 2013
    Publication date: November 28, 2013
    Inventors: Rebecca Taub, Tilmann Brotz, John Franc, Lawrence K. Cohen, Hemantkumar H. Patel, Sanjay R. Chemburkar, David P. Sawick
  • PHENYLALKYL N-HYDROXYUREAS FOR TREATING LEUKOTRIENE RELATED PATHOLOGIES
    Publication number: 20130190514
    Abstract: The method of treating patients by administering N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea for treatment of leukotriene related pathologies, and compositions for this use.
    Type: Application
    Filed: July 25, 2011
    Publication date: July 25, 2013
    Applicant: TALLIKUT PHARMACEUTICALS, INC.
    Inventors: Rebecca Taub, Tilmann Brotz, John Franc, Larry Cohen, Hemantkumar H. Patel, Sanjay R. Chemburkar, David P. Sawick
  • Process for the synthesis of (2S,3AR,7AS)-octahydro-1H-indole carboxylic acid as an intermediate for trandolapril
    Patent number: 8288565
    Abstract: A process for the preparation of (2S,3aR,7aS)-octahydro-1H-indole-20carboxylic acid hydrochloride.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: October 16, 2012
    Assignee: Abbott Laboratories
    Inventors: Sanjay R. Chemburkar, Rajarathnam E. Reddy, Douglas M. Reamer, John T. Pavlina, Stephen S. Ulrey, Brian J. Kotecki
  • Polymorph of a Pharmaceutical
    Publication number: 20120232284
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Application
    Filed: May 25, 2012
    Publication date: September 13, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: John F. Bauer, Azita Saleki-Gerhardt, Bikshandarkoil A. Narayanan, Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek, Philip E. Bauer, Kimberly A. Allen
  • Polymorph of a pharmaceutical
    Patent number: 8193367
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: June 5, 2012
    Assignee: Abbott Laboratories
    Inventors: John F. Bauer, Azita Saleki-Gerhardt, Bikshandarkoil A. Narayanan, Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek, Philip E. Bauer, Kimberly A. Allen
  • One pot synthesis of tetrazole derivatives of rapamycin
    Patent number: 8129521
    Abstract: A single-step, one-pot process to obtain zotarolimus and other rapamycin derivatives on large scale is presented, which improves currently available synthesis schemes. In one embodiment, dried rapamycin is dissolved in isopropylacetate (IPAc). The solution is cooled, and 2,6-Lutidine is added, followed slowly adding triflic anhydride at ?30° C. Salts are then removed by filtration. Tetrazole, followed by a tert-base diisopropylethylamine (DIEA) is added to the triflate solution. After incubation at room temperature, the product is concentrated and purified by a silica gel column using THF/heptane as eluant. The fractions containing the product are collected, concentrated, and purified again using an acetone/heptane column. The product containing fractions are concentrated. The product is dissolved in t-BME and precipitated with heptane. The solids are dissolved in acetone, treated with butylated-hydroxy toluene (BHT), and the solution concentrated.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: March 6, 2012
    Assignee: Abbott Laboratories
    Inventors: Madhup K. Dhaon, Chi-nung Hsiao, Subhash R. Patel, Peter J. Bonk, Sanjay R. Chemburkar, Yong Y. Chen
  • PHENYLALKYL N-HYDROXYUREAS FOR TREATING LEUKOTRIENE RELATED PATHOLOGIES
    Publication number: 20120029048
    Abstract: The method of treating patients by administering N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea for treatment of leukotriene related pathologies and compositions for this use.
    Type: Application
    Filed: February 10, 2011
    Publication date: February 2, 2012
    Applicant: VIA Pharmaceuticals, Inc.
    Inventors: Rebecca Taub, Tilmann Brotz, John Franc, Larry Cohen, Hemantkumar H. Patel, Sanjay R. Chemburkar, David P. Sawick
  • PROCESS FOR THE PREPARATION OF SCYLLO-INOSITOL
    Publication number: 20110201060
    Abstract: This invention pertains to a process for manufacturing scyllo-Inositol. Specifically, the current invention pertains to a process for converting myo-Inositol to scyllo-Inositol using a bioconversion process.
    Type: Application
    Filed: February 14, 2011
    Publication date: August 18, 2011
    Applicant: Abbott Laboratories
    Inventors: Rajarathnam E. Reddy, Sanjay R. Chemburkar, Douglas R. Spaulding, Yi Pan, Lei Cao, Jose A. Restituyo, Richard Lorenzini, Michael DeMarco
  • Spirocyclopropyl amides and acids and their therapeutic applications
    Patent number: 7932245
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.
    Type: Grant
    Filed: October 22, 2003
    Date of Patent: April 26, 2011
    Assignee: Abbott Laboratories
    Inventors: Youssef L. Bennani, William H. Bunnelle, Sou-Jen Chang, Sanjay R. Chemburkar, Jinhua Chen, Michael J. Dart, Dilinie P. Fernando, Yi-Yin Ku, Mark Lockwood, Lei Wang
  • PROCESS FOR THE SYNTHESIS OF (2S,3AR,7AS)-OCTAHYDRO-1H-INDOLE CARBOXYLIC ACID AS AN INTERMEDIATE FOR TRANDOLAPRIL
    Publication number: 20110065930
    Abstract: A process for the preparation of (2S,3aR,7aS)-octahydro-1H-indole-20carboxylic acid hydrochloride.
    Type: Application
    Filed: July 16, 2010
    Publication date: March 17, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Sanjay R. Chemburkar, Rajarathnam E. Reddy, Douglas M. Reamer, John T. Pavlina, Stephen S. Ulrey, Brian J. Kotecki
  • ONE POT SYNTHESIS OF TETRAZOLE DERIVATIVES OF RAPAMYCIN
    Publication number: 20100204466
    Abstract: A single-step, one-pot process to obtain zotarolimus and other rapamycin derivatives on large scale is presented, which improves currently available synthesis schemes. In one embodiment, dried rapamycin is dissolved in isopropylacetate (IPAc). The solution is cooled, and 2,6-Lutidine is added, followed slowly adding triflic anhydride at ?30° C. Salts are then removed by filtration. Tetrazole, followed by a tert-base diisopropylethylamine (DIEA) is added to the triflate solution. After incubation at room temperature, the product is concentrated and purified by a silica gel column using THF/heptane as eluant. The fractions containing the product are collected, concentrated, and purified again using an acetone/heptane column. The product containing fractions are concentrated. The product is dissolved in t-BME and precipitated with heptane. The solids are dissolved in acetone, treated with butylated-hydroxy toluene (BHT), and the solution concentrated.
    Type: Application
    Filed: February 23, 2010
    Publication date: August 12, 2010
    Inventors: Madhup K. Dhaon, Chi-nung Hsiao, Subhash R. Patel, Peter J. Bonk, Sanjay R. Chemburkar, Yong Chen
  • Polymorph of a Pharmaceutical
    Publication number: 20100144804
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Application
    Filed: December 22, 2009
    Publication date: June 10, 2010
    Applicant: Abbott Laboratories
    Inventors: John F. Bauer, Azita Saleki-Gerhardt, Bikshandarkoil A. Narayanan, Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek, Philip E. Bauer, Kimberly A. Allen
  • One pot synthesis of tetrazole derivatives of rapamycin
    Patent number: 7700614
    Abstract: A single-step, one-pot process to obtain zotarolimus and other rapamycin derivatives on large scale is presented, which improves currently available synthesis schemes. In one embodiment, dried rapamycin is dissolved in isopropylacetate (IPAc). The solution is cooled, and 2,6-Lutidine is added, followed slowly adding triflic anhydride at ?30° C. Salts are then removed by filtration. Tetrazole, followed by a tert-base diisopropylethylamine (DIEA) is added to the triflate solution. After incubation at room temperature, the product is concentrated and purified by a silica gel column using THF/heptane as eluant. The fractions containing the product are collected, concentrated, and purified again using an acetone/heptane column. The product containing fractions are concentrated. The product is dissolved in t-BME and precipitated with heptane. The solids are dissolved in acetone, treated with butylated-hydroxy toluene (BHT), and the solution concentrated.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: April 20, 2010
    Assignee: Abbott Laboratories
    Inventors: Madhup K. Dhaon, Chi-nung Hsiao, Subhash R. Patel, Peter J. Bonk, Sanjay R. Chemburkar, Yong Chen
  • Polymorph of a pharmaceutical
    Patent number: 7659405
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: February 9, 2010
    Assignee: Abbott Laboratories
    Inventors: John F. Bauer, Azita Saleki-Gerhardt, Bikshandarkoil A. Narayanan, Sanjay R. Chemburkar, Ketan M. Patel, Harry O. Spiwek, Philip E. Bauer, Kimberly A. Allen
  • FERMENTATION BROTH EXTRACTION OF K-252A
    Publication number: 20090239271
    Abstract: Methods for separating K-252a from the cell mass of its parent fermentation broth are disclosed.
    Type: Application
    Filed: May 11, 2009
    Publication date: September 24, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Sanjay R. Chemburkar, Stephen S. Ulrey, Julie J. Pruyne
  • One pot synthesis of tetrazole derivatives of sirolimus
    Publication number: 20080167335
    Abstract: A single-step, one-pot process to obtain zotarolimus and other rapamycin derivatives on large scale is presented, which improves currently available synthesis schemes. In one embodiment, dried rapamycin is dissolved in isopropylacetate (IPAc). The solution is cooled, and 2,6-Lutidine is added, followed slowly adding triflic anhydride at ?30° C. Salts are then removed by filtration. Tetrazole, followed by a tert-base diisopropylethylamine (DIEA) is added to the triflate solution. After incubation at room temperature, the product is concentrated and purified by a silica gel column using THF/heptane as eluant. The fractions containing the product are collected, concentrated, and purified again using an acetone/heptane column. The product containing fractions are concentrated. The product is dissolved in t-BME and precipitated with heptane. The solids are dissolved in acetone, treated with butylated-hydroxy toluene (BHT), and the solution concentrated.
    Type: Application
    Filed: December 14, 2005
    Publication date: July 10, 2008
    Inventors: Madhup K. Dhaon, Chi-nung Hsiao, Subhash R. Patel, Peter J. Bonk, Sanjay R. Chemburkar, Yong Y. Chen
  • Polymorph of a pharmaceutical
    Patent number: 7183416
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: February 27, 2007
    Assignee: Abbott Laboratories
    Inventors: Sanjay R. Chemburkar, Ketan Patel, Harry O. Spiwek
  • Polymorph of a pharmaceutical
    Patent number: 7148359
    Abstract: A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
    Type: Grant
    Filed: May 4, 2005
    Date of Patent: December 12, 2006
    Assignee: Abbott Laboratories
    Inventors: Sanjay R. Chemburkar, Ketan Patel
  • Fused cycloalkyl amides and acids and their therapeutic applications
    Publication number: 20040209859
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: October 22, 2003
    Publication date: October 21, 2004
    Inventors: Youssef L. Bennani, Sou-Jen Chang, Sanjay R. Chemburkar, Michael J. Dart, Dilinie P. Fernando, Timothy A. Grieme
  • Cycloalkylamides and their therapeutic applications
    Publication number: 20040209858
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: October 22, 2003
    Publication date: October 21, 2004
    Inventors: Youssef L. Bennani, Steve A. Chamberlin, Sanjay R. Chemburkar, Jinhua Chen, Michael J. Dart, Ashok K. Gupta, Lei Wang