Patents by Inventor Sanjay Ramesh Varma

Sanjay Ramesh Varma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorescence microscopy system and methods based on stimulated emission
    Patent number: 11009463
    Abstract: Fluorescence imaging based on stimulated emission. In one example a system includes an excitation source (110) that excites fluorescent markers (122) in a sample (120) with an excitation beam (112), a stimulation source (130) that stimulates the excited fluorescent markers (122) to produce stimulated emission (124), and an objective lens (150) that receives the stimulation beam (132) and the stimulated emission (124). The system further includes a phase shifting and attenuation apparatus (200) configured to receive the stimulation beam (132) and the stimulated emission (124) from the objective lens (150), to attenuate the stimulation beam (132), and to induce a relative phase shift between a reference beam (optionally being at least a portion of the stimulation beam) and the stimulated emission, thereby causing constructive interference between the reference beam and the stimulated emission.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: May 18, 2021
    Assignee: CALICO LIFE SCIENCES LLC
    Inventors: Andrew Gregory York, Sanjay Ramesh Varma
  • FLUORESCENCE MICROSCOPY SYSTEM AND METHODS BASED ON STIMULATED EMISSION
    Publication number: 20200378895
    Abstract: Fluorescence imaging based on stimulated emission. In one example a system includes an excitation source (110) that excites fluorescent markers (122) in a sample (120) with an excitation beam (112), a stimulation source (130) that stimulates the excited fluorescent markers (122) to produce stimulated emission (124), and an objective lens (150) that receives the stimulation beam (132) and the stimulated emission (124). The system further includes a phase shifting and attenuation apparatus (200) configured to receive the stimulation beam (132) and the stimulated emission (124) from the objective lens (150), to attenuate the stimulation beam (132), and to induce a relative phase shift between a reference beam (optionally being at least a portion of the stimulation beam) and the stimulated emission, thereby causing constructive interference between the reference beam and the stimulated emission.
    Type: Application
    Filed: April 11, 2018
    Publication date: December 3, 2020
    Inventors: Andrew Gregory York, Sanjay Ramesh Varma