Abstract: A blood processing assembly comprises a frame rotatable about a rotational axis and a blood processing chamber carried by the frame for rotation about the rotational axis. An umbilicus has one end coupled to the blood processing chamber along the rotational axis and an opposite end held in a non-rotating position along the rotational axis. A mid region of the umbilicus extends, at least in part, outside the rotational axis. The frame carries at least one support channel, which is sized and configured to engage the mid region of the umbilicus. The support channel includes a side edge that is sized and configured to self-load the mid region of the umbilicus into the support channel in response to rotation of the frame in a designated direction.

Abstract: A blood separation chamber comprises a base that includes formed walls that define a hub. A separation channel extends about the hub. A flow passage extends between the hub and the separation channel. The hub enables attachment of external tubing to convey blood to and from the separation channel through the hub.

Abstract: A blood processing assembly comprises a frame rotatable about a rotational axis and a blood processing chamber carried by the frame for rotation about the rotational axis. An umbilicus has one end coupled to the blood processing chamber along the rotational axis and an opposite end held in a non-rotating position along the rotational axis. A mid region of the umbilicus extends, at least in part, outside the rotational axis. The frame carries at least one support channel, which is sized and configured to engage the mid region of the umbilicus. The support channel includes a side edge that is sized and configured to self-load the mid region of the umbilicus into the support channel in response to rotation of the frame in a designated direction.

Abstract: An optical sensing assembly is adapted for use in association with a separation device having a separation zone in which red blood cells and plasma are separated from blood. The assembly comprises a first optical sensing unit associated with a red blood cell outlet path that removes red blood cells from the separation zone. The assembly also comprises a second optical sensing unit associated with a plasma outlet path that removes plasma from the blood separation zone. The assembly further comprises a controller coupled to the first and second optical sensing units having different selectable control functions for operating the first and second optical sensing units in at least two different sensing modes.

Abstract: A blood separation chamber comprises a base that includes formed walls that define a hub. A separation channel extends about the hub. A flow passage extends between the hub and the separation channel. The hub enables attachment of external tubing to convey blood to and from the separation channel through the hub.

Abstract: A pneumatic pump manifold disposable system, configured as a cassette, is used for the purpose of red cell and plasma apheresis. The cassette integrates a separation device, manifold system, macro-aggregate filter, and five pumping chambers for the purpose of separating plasma and red cells from the whole blood. The cassette system, with the separation device directly attached without tubing, simplifies the loading of the disposable set into the hardware, and reduces the manufacturing complexity of the set. The system allows for plasma, plasma and red cells, or just red cells to be stored in long term storage containers after a procedure.

Abstract: A blood separation chamber comprises a base that includes formed walls that define a hub. A separation channel extends about the hub. A flow passage extends between the hub and the separation channel. The hub enables attachment of external tubing to convey blood to and from the separation channel through the hub.

Abstract: A blood separation assembly comprises a blood processing chamber having a base including formed walls that define a separation channel. A centrifuge rotor is rotatable about a rotational axis. A latch assembly comprises a latch arm that is pivotally mounted on the centrifuge rotor. The latch arm can be moved between a chamber-retaining position engaging the blood processing chamber, to secure the blood processing chamber to the centrifuge rotor, and a chamber- releasing position free of engagement with the blood processing chamber, to enable removal of the blood processing chamber from the centrifuge rotor. The latch assembly also includes a pawl movable on the centrifuge rotor between a first position adjacent the latch arm and a second position spaced from the latch arm. The pawl includes a locking element that engages the latch arm when the latch arm is in the chamber-retaining position, to resist movement of the latch arm toward the chamber-releasing position.

Abstract: A blood separation chamber comprises a base that includes formed walls that define a hub. A separation channel extends about the hub. A flow passage extends between the hub and the separation channel. The hub enables attachment of external tubing to convey blood to and from the separation channel through the hub.

Abstract: A tubing has members located on the inside surface of a tubing. The flow through the tubing is completely occluded when the tubing is clamped due to the members filling channels around the clamped site. Reduced clamping pressure is required to fully occlude the flow through the tubing. The tubing undergoes less deformation upon clamping and returns to its pre-clamped form upon recovery.