Abstract: A smart device audio power harvesting glucose meter and a system and method for blood glucose measurement and monitoring. The glucose meter operates by harvesting the micro amp power from the audio port of a smart phone or other handheld smart device and does not need batteries or other power sources for its operation. A smart glucose monitoring application downloaded and embedded in the smart phone or other hand held smart device stores results of the glucose measurements in a personalized cloud database to be accessed by the user and shared with physicians, emergency personnel, friends, or family members if needed through automated phone calls, SMS/text, or emails. The smart glucose monitoring application is self learning and has an option for self ordering test strips based on the needs of the user.