Abstract: This invention relates to bis-azo colorants for use as bluing agents, laundry care compositions comprising bis-azo colorants that may serve as bluing agents, processes for making such bluing agents and laundry care compositions and methods of using the same. The bluing agents are generally comprised of at least two components: at least one chromophore component and at least one polymeric component. These bluing agents are advantageous in providing a whitening effect to fabrics, while not building up over time and causing undesirable blue discoloration to the treated fabrics.

Abstract: There is provided a process for the preparation of AZD5363, or a salt of AZD5363, comprising: (a) the reaction of 8-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-oxa-1,8-diazaspiro[4.5]decane-2,4-dione: or a salt thereof, with (S)-3-amino-3-(4-chlorophenyl)propan-1-ol, or a salt thereof, in the presence of base; and (b) either isolating AZD5363 or isolating AZD5363 as a salt. 8-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-oxa-1,8-diazaspiro[4.

Abstract: Various embodiments include an endoscopic device. A sheath may enclose the device and may thereby guard against environmental contamination. The sheath may include one or more channels for transmission of instruments and/or solution to and from the body. The sheath may be disposable. A stopper unit may reduce fluid leakage from inside a body cavity during a procedure. The stopper unit may include a serrated outer contour to assist in catching at a body orifice. The stopper unit may have a perforable inner barrier designed to reseal about a probing portion inserted through the stopper unit.

Abstract: A method includes receiving, at a device, a plurality of image frames corresponding to a video stream. The plurality of image frames include a first image frame having a first resolution and a second image frame having a second resolution that is lower than the first resolution. The method also includes detecting, at the device, a trigger by analyzing the second image frame. The method further includes designating, at the device, the first image frame as an action frame based on the trigger.

Abstract: Embodiments of the invention relate a hybrid hardware and software implementation of transactional memory accesses in a computer system. A processor including a transactional cache and a regular cache is utilized in a computer system that includes a policy manager to select one of a first mode (a hardware mode) or a second mode (a software mode) to implement transactional memory accesses. In the hardware mode the transactional cache is utilized to perform read and write memory operations and in the software mode the regular cache is utilized to perform read and write memory operations.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for enabling screen-specific user interfacing with elements of viewable screens presented by an electronic device are disclosed. In one aspect, a method includes the actions of identifying a character sequence representing a first input that is received while displaying a viewable screen having at least one selectable viewable element. The actions further include accessing an electronic file that provides a text representation of one or more of the at least one selectable viewable element. The actions further include comparing the character sequence to the text representation. The actions further include selecting, within the viewable screen, a selectable viewable element whose text representation matches the character sequence. The actions further include triggering any action linked to the selecting the selectable viewable element.

Abstract: Embodiments of the invention relate a hybrid hardware and software implementation of transactional memory accesses in a computer system. A processor including a transactional cache and a regular cache is utilized in a computer system that includes a policy manager to select one of a first mode (a hardware mode) or a second mode (a software mode) to implement transactional memory accesses. In the hardware mode the transactional cache is utilized to perform read and write memory operations and in the software mode the regular cache is utilized to perform read and write memory operations.

Abstract: The present invention provides an improved method for the purification of monoclonal antibody from cell culture. Process of purification of the desired monoclonal antibody comprises affinity, hydrophobic interaction and optionally ion exchange column chromatography. It provides more than 99% purity of the desired monoclonal antibody.

Abstract: A client device is tracked over a period of time using “refresh tokens” that are exchanged in conjunction with routine client-server communications. Each communication cycle between client and server includes a refresh token that is recorded at the server. The recorded refresh tokens are mapped to both server- and client-generated device identifiers. As communications between client and server occur, a chain of tokens, one for each communication cycle, is progressively recorded at the server. If the server receives a token that is outdated with respect to that which is otherwise expected based on the progression of the recorded chain, this suggests that the received communication was transmitted from a device that is a clone of another client device. A more robust device identification framework is therefore achieved by using a combination of device identifiers and tokens exchanged between client and server.

Abstract: An apparatus is disclosed that includes a fluid inlet in fluid communication with a valve assembly, the valve assembly structured to selectively permit the flow of a motive fluid from the fluid inlet to a fluid driven motor, wherein the valve assembly further includes a first plunger including a plurality of axially extending fluid channels, wherein the plunger is selectively movable by an actuator in a manner such that as the plunger is displaced farther away from a closed position, the number of axially extending fluid channels placed in fluid communication with the fluid inlet increases, and wherein the axially extending fluid channels permit the flow of the motive fluid from the fluid inlet to the fluid driven motor.

Abstract: A neural network is disclosed. The neural network comprises a plurality of optogenetically modified neural cells being three-dimensionally distributed in a hydrogel medium and being disconnected from any solid support having a shear modulus above 1 GPa.

Abstract: In one embodiment, a method includes a request that is obtained by a call center system from a customer. The method also includes identifying a first set of experts that includes at least a first expert suitable for, or capable of, processing the request. The first expert is offline with respect to the call center system. An offer task is created and provided to the first set of experts. The offer task identifies the request and initiates the scheduling of a callback to address the request.

Abstract: In one embodiment, a processor may include a vector unit to perform operations on multiple data elements responsive to a single instruction, and a control unit coupled to the vector unit to provide the data elements to the vector unit, where the control unit is to enable an atomic vector operation to be performed on at least some of the data elements responsive to a first vector instruction to be executed under a first mask and a second vector instruction to be executed under a second mask. Other embodiments are described and claimed.

Abstract: A turbine disc assembly is provided. The turbine disc assembly includes a first rotor disc, a second rotor disc, and a spacer disc coupled between the first and second rotor discs along an axis to define a plenum. The spacer disc has an inner surface with a radius from the axis. A first cooling channel defined between the first rotor disc and the spacer disc is in flow communication with the plenum. The second rotor disc includes a deflector having a deflection surface positioned within the plenum such that the deflection surface is oriented towards the first cooling channel at an acute angle relative to the radius of the inner surface of the spacer disc.

Abstract: Disclosed is a technology for publishing subscriptions in a publish-subscribe system in accordance with subscription groups. The technology may include (i) determining a consumption characteristic by which each of multiple subscribers in a publish-subscribe system consumes a subscription published by a publisher; (ii) identifying the subscribers whose consumption characteristics satisfy a specified similarity criterion; (iii) defining multiple subscription groups, each of which includes subscriptions of those of the subscribers whose consumption characteristics satisfy the specified similarity criterion; (iv) storing the subscriptions in multiple logical partitions of a storage system where each of the logical partitions contains a separate non-overlapping subset of the subscriptions; and (v) transmitting the subscriptions to the subscribers in accordance with the subscription groups.

Abstract: A self-adaptive control system based on proportional-integral (PI) control theory for dynamic capacity management of latency-sensitive application servers (e.g., application servers associated with a social networking application) are disclosed. A centralized controller of the system can adapt to changes in request rates, changes in application and/or system behaviors, underlying hardware upgrades, etc., by scaling the capacity of a cluster up or down so that just the right amount of capacity is maintained at any time. The centralized controller uses information relating to a current state of the cluster and historical information relating to past state of the cluster to predict a future state of the cluster and use that prediction to determine whether to scale up or scale down the current capacity to reduce latency and maximize energy savings. A load balancing system can then distribute traffic among the servers in the cluster using any load balancing methods.

Abstract: The present invention deals with examination of the alterability of part, or whole, of the surfaces of beta sheet-based protein structures, focusing especially on enzymes. The alteration is done by supplanting/transplanting a part, or whole, of the surface of one protein onto the surface of a homologous protein of superimposable polypeptide backbone, by exploiting the structural features of beta sheets to alter only the regions of the surface involved in substrate/ligand binding and catalysis. The transplantation involves replacement of a selected set of non-contiguous residues constituting the surface regions desired to be altered in one enzyme/protein, by a set of non-contiguous residues located at analogous positions in the other enzyme/protein, in a manner that is likely to facilitate folding and function of the new protein formed by combining residues from both enzymes/proteins.

Abstract: Lock-out mechanisms for driver handheld mobile devices are provided to prevent operation of one or more functions of handheld mobile devices by drivers when operating vehicles based on device location data and device motion data within a vehicle by wirelessly communicating with at least one wireless station access point located inside of the vehicle. The lock-out mechanisms disable the ability of a handheld mobile device to perform certain functions, such as texting or browsing, while one is driving. In one embodiment, a handheld mobile device may provide a lock-out mechanism without requiring any modifications or additions to a vehicle by using a motion analyzer, a mobile device position locator and a lock-out mechanism. In other embodiments, the handheld mobile device may provide a lock-out mechanism with modifications or additions to the vehicle, including the use of wireless signals transmitted by the vehicle or by a wireless station access point disposed within the vehicle.

Abstract: A network access system, e.g. a network hotspot, requires a mobile network access device, e.g. a smart phone or WiFi only device, to provide a network access standard designation and/or a device identification datum to gain access to network services. The network access standard designation may be provided by the mobile network access device to an online signup server via a EKU_key_purpose field of a PKCS10 certificate signing request. The device identification datum may be provided to the OSU via a subject field of the signing request. The OSU may require that the device identification datum be the same as a device identification datum provided by the mobile network access device prior to the mobile network access device requesting a signed network access certificate.