Patents by Inventor Sanjeev Noel

Sanjeev Noel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR PREVENTING AND TREATING ACUTE KIDNEY INJURY
    Publication number: 20240408114
    Abstract: Provided are glutamine antagonists and prodrugs of glutamine analogs having formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R2?, and X are as defined as set forth in the specification, for use in preventing and/or treating acute kidney injury.
    Type: Application
    Filed: November 4, 2022
    Publication date: December 12, 2024
    Inventors: Hamid RABB, Barbara SLUSHER, Jonathan D. POWELL, Kyungho LEE, Elizabeth THOMPSON, Sanjeev NOEL, Sepideh GHARAIE
  • COMPOSITIONS AND METHODS FOR THE STUDY AND TREATMENT OF ACUTE KIDNEY INJURY
    Publication number: 20200120909
    Abstract: The present invention relates to the field of nephrology. More specifically, the present invention provides compositions and methods useful for the study and treatment of acute kidney injury. In one embodiment, the present invention provides a knockout animal whose genome comprises a deletion of exon 2 and exon 3 of kelch-like ECH-associated protein 1 (KEAP1) in T-cells. In another embodiment, a method for treating a subject diagnosed with AKI comprising the steps of (a) isolating T-cells from the subject; (b) activating Nrf2 expression in the isolated T-cells; and (c) administering the T-cells back to the subject.
    Type: Application
    Filed: December 23, 2019
    Publication date: April 23, 2020
    Inventors: Hamid Rabb, Sanjeev Noel, Maria N. Martina-Lingua, Lorraine C. Racusen, Abdel Rahim Hamad, Samatha Bandapalle
  • COMPOSITIONS AND METHODS FOR THE STUDY AND TREATMENT OF ACUTE KIDNEY INJURY
    Publication number: 20160120158
    Abstract: The present invention relates to the field of nephrology. More specifically, the present invention provides compositions and methods useful for the study and treatment of acute kidney injury. In one embodiment, the present invention provides a knockout animal whose genome comprises a deletion of exon 2 and exon 3 of kelch-like ECH-associated protein 1 (KEAP1) in T-cells. In another embodiment, a method for treating a subject diagnosed with AKI comprising the steps of (a) isolating T-cells from the subject; (b) activating Nrf2 expression in the isolated T-cells; and (c) administering the T-cells back to the subject.
    Type: Application
    Filed: November 3, 2015
    Publication date: May 5, 2016
    Inventors: Hamid Rabb, Sanjeev Noel, Maria N. Martina-Lingua, Lorraine C. Racusen, Abdel Rahim Hamad, Samatha Bandapalle