Patents by Inventor Sanji Tokuno
Sanji Tokuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8956650Abstract: An intrabuccally rapidly disintegrating tablet which is manufactured by a simple method, has an enough practical hardness and is rapidly disintegrated in the buccal cavity and its production method. The intrabuccally rapidly disintegrating tablet is produced by growing a powder material into a granulated material with a fixed particle diameter, the powder material including a sugar alcohol or a saccharide as main ingredient, each of which is first particle having an average particle diameter of not more than 30 ?m, by mixing thus obtained granulated material with an active ingredient and a disintegrant, and by compressing the mixture into a predetermined shape.Type: GrantFiled: January 17, 2013Date of Patent: February 17, 2015Assignee: Kyowa Hakko Kirin Co., Ltd.Inventors: Motohiro Ohta, Eiji Hayakawa, Kunio Ito, Sanji Tokuno, Kiyoshi Morimoto, Yasushi Watanabe
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Patent number: 8945618Abstract: An intrabuccally rapidly disintegrating tablet which is manufactured by a simple method, has an enough practical hardness and is rapidly disintegrated in the buccal cavity and its production method. The intrabuccally rapidly disintegrating tablet is produced by growing a powder material into a granulated material with a fixed particle diameter, the powder material including a sugar alcohol or a saccharide as main ingredient, each of which is first particle having an average particle diameter of not more than 30 ?m, by mixing thus obtained granulated material with an active ingredient and a disintegrant, and by compressing the mixture into a predetermined shape.Type: GrantFiled: March 13, 2014Date of Patent: February 3, 2015Assignee: Kyowa Hakko Kirin Co., Ltd.Inventors: Motohiro Ohta, Eiji Hayakawa, Kunio Ito, Sanji Tokuno, Kiyoshi Morimoto, Yasushi Watanabe
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Publication number: 20140193496Abstract: An intrabuccally rapidly disintegrating tablet which is manufactured by a simple method, has an enough practical hardness and is rapidly disintegrated in the buccal cavity and its production method. The intrabuccally rapidly disintegrating tablet is produced by growing a powder material into a granulated material with a fixed particle diameter, the powder material including a sugar alcohol or a saccharide as main ingredient, each of which is first particle having an average particle diameter of not more than 30 ?m, by mixing thus obtained granulated material with an active ingredient and a disintegrant, and by compressing the mixture into a predetermined shape.Type: ApplicationFiled: March 13, 2014Publication date: July 10, 2014Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Motohiro OHTA, Eiji HAYAKAWA, Kunio ITO, Sanji TOKUNO, Kiyoshi MORIMOTO, Yasushi WATANABE
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Patent number: 8357396Abstract: An intrabuccally rapidly disintegrating tablet which is manufactured by a simple method, has an enough practical hardness and is rapidly disintegrated in the buccal cavity and its production method. The intrabuccally rapidly disintegrating tablet is produced by growing a powder material into a granulated material with a fixed particle diameter, the powder material including a sugar alcohol or a saccharide as main ingredient, each of which is first particle having an average particle diameter of not more than 30 ?m, by mixing thus obtained granulated material with an active ingredient and a disintegrant, and by compressing the mixture into a predetermined shape.Type: GrantFiled: October 26, 2011Date of Patent: January 22, 2013Assignee: Kyowa Hakko Kirin Co., Ltd.Inventors: Motohiro Ohta, Eiji Hayakawa, Kunio Ito, Sanji Tokuno, Kiyoshi Morimoto, Yasushi Watanabe
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Publication number: 20120135076Abstract: An intrabuccally rapidly disintegrating tablet which is manufactured by a simple method, has an enough practical hardness and is rapidly disintegrated in the buccal cavity and its production method. The intrabuccally rapidly disintegrating tablet is produced by growing a powder material into a granulated material with a fixed particle diameter, the powder material including a sugar alcohol or a saccharide as main ingredient, each of which is first particle having an average particle diameter of not more than 30 ?m, by mixing thus obtained granulated material with an active ingredient and a disintegrant, and by compressing the mixture into a predetermined shape.Type: ApplicationFiled: October 26, 2011Publication date: May 31, 2012Inventors: Motohiro OHTA, Eiji Hayakawa, Kunio Ito, Sanji Tokuno, Kiyoshi Morimoto, Yasushi Watanabe
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Patent number: 8071128Abstract: An intrabuccally rapidly disintegrating tablet which is manufactured by a simple method, has an enough practical hardness and is rapidly disintegrated in the buccal cavity and its production method. The intrabuccally rapidly disintegrating tablet is produced by growing a powder material into a granulated material with a fixed particle diameter, the powder material including a sugar alcohol or a saccharide as main ingredient, each of which is first particle having an average particle diameter of not more than 30 ?m, by mixing thus obtained granulated material with an active ingredient and a disintegrant, and by compressing the mixture into a predetermined shape.Type: GrantFiled: June 20, 2003Date of Patent: December 6, 2011Assignee: Kyowa Hakko Kirin Co., Ltd.Inventors: Motohiro Ohta, Eiji Hayakawa, Kunio Ito, Sanji Tokuno, Kiyoshi Morimoto, Yasushi Watanabe
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Publication number: 20030215500Abstract: An intrabuccally rapidly disintegrating tablet which is manufactured by a simple method, has an enough practical hardness and is rapidly disintegrated in the buccal cavity and its production method. The intrabuccally rapidly disintegrating tablet is produced by growing a powder material into a granulated material with a fixed particle diameter, the powder material including a sugar alcohol or a saccharide as main ingredient, each of which is first particle having an average particle diameter of not more than 30 &mgr;m, by mixing thus obtained granulated material with an active ingredient and a disintegrant, and by compressing the mixture into a predetermined shape.Type: ApplicationFiled: June 20, 2003Publication date: November 20, 2003Inventors: Motohiro Ohta, Eiji Hayakawa, Kunio Ito, Sanji Tokuno, Kiyoshi Morimoto, Yasushi Watanabe
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Patent number: 6464737Abstract: A production method and system for granulating powdered material wherein powdered material is fluidized by applying heated pulsating vibration air, and the fluidized powdered material is suspended up and down at a regular cycle by means of heated pulsating vibration air, the aggregated material is compressed by further vibration of pulsating vibration air, whereby the aggregated powdered material is efficiently made into granulated material with high density and rather small specific volume without causing projection on the surface and without being made porous. The production system is comprised of a granulation tank for storing powdered material to be granulated, the granulation tank having a supply port for introducing heated air at the bottom thereof, a discharge port for discharging the introduced heated air at the top thereof, and a fluidization bed provided above the supply port for receiving the powdered material.Type: GrantFiled: May 28, 1998Date of Patent: October 15, 2002Assignees: Kyowa Hakko Kogyo Co., Ltd., Kabushikikaisha Matsui SeisakushoInventors: Kiyoshi Morimoto, Hirokazu Yoshimoto, Sanji Tokuno, Hiroshi Tada, Kazue Murata
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Patent number: 6432534Abstract: A method for producing tablet including active component, diluting agent, and lubricant by means of a tabletting machine provided with punches and dies, comprising steps of; preparing molding material including active component, diluting anent, and a part of lubricant; applying most of the remaining amount of the lubricant on surfaces of the punches and a surface of the die; and tabletting the molding material by means of the punches on which surfaces the lubricant is applied and the die on which surface the lubricant is appliedType: GrantFiled: September 14, 2000Date of Patent: August 13, 2002Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Eiji Hayakawa, Motohiro Ohta, Hiroyuki Morimoto, Kiyoshi Morimoto, Yasushi Watanabe, Kunio Ito, Sanji Tokuno
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Patent number: 6302573Abstract: A mixing and blending method for powdered or granular material includes supplying pulsating vibration air into an airtight tank from a bottom thereof. An airtight tank having a porous bottom plate on which the material is stored is provided for the mixing and blending method. In the system pulsating vibration air is generated by periodically increasing and decreasing the amount of blowing air at a low frequency. Pulsating vibration air is introduced into the airtight tank from the bottom of the airtight tank so as to generate air flow going upward through the porous bottom of the airtight tank. As a result, powdered or granular material stored on the porous bottom plate in the airtight tank is uniformly mixed and blended in the airtight tank while continuously moving up and down as in a convectional manner.Type: GrantFiled: April 12, 1999Date of Patent: October 16, 2001Assignees: Kyowa Hakko Kogyo Co., Ltd., Kabushikikaisha Matsui SeisakushoInventors: Kiyoshi Morimoto, Yasushi Watanabe, Yoshika Sanada, Sanji Tokuno, Kazue Murata
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Publication number: 20010014340Abstract: A tablet comprising sugar alcohol or saccaride having an average particle diameter of not more than 30 &mgr;m, an active ingredient, and a disintegrant. It is an intraorally rapidly disintegrable tablet which does not require a special pharmaceutical manufacturing technology and can be simply and easily produced by a normal equipment.Type: ApplicationFiled: June 4, 1999Publication date: August 16, 2001Inventors: MOTOHIRO OHTA, EIJI HAYAKAWA, KUNIO ITO, SANJI TOKUNO, KIYOSHI MORIMOTO, YASUSHI WATANABE
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Patent number: 6062826Abstract: A pulsating vibration air generator in which wave height, frequency and wave shape of the pulsating vibration air can be optionally modified and such pulsating vibration air can be periodically and continuously emitted. The pulsating vibration air generator has a valve chamber with an inlet port and an outlet port where a valve plug and a valve seat with a control opening are provided and a cam mechanism which moves the valve plug to open or close the opening of the valve seat, whereby positive or negative pulsating vibration air is emitted from the outlet port while pressurized air is supplied into the inlet port or air is sucked from the inlet port.Type: GrantFiled: September 16, 1996Date of Patent: May 16, 2000Assignees: Kyowa Hakko Kogyo Co., Ltd., Kabushikikaisha Matsui SeisakushoInventors: Kiyoshi Morimoto, Yasushi Watanabe, Yoshika Sanada, Sanji Tokuno, Kazue Murata
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Patent number: 5996902Abstract: A sprayer and method for spraying powdered material activated by pulsating vibration air. The sprayer comprises an elastic membrane, a storage tank for storing powdered material provided with the elastic membrane at the bottom opening, and a pulsating vibration air generator for supplying pulsating vibration air to the elastic membrane. The sprayer so constructed is designed to uniformly and diffusely spray the powdered material stored in the storage tank when the elastic membrane is forcedly vibrated up and down in compliance with the frequency of the pulsating vibration air by receiving pulsating vibration air from the pulsating vibration air generator.Type: GrantFiled: June 19, 1997Date of Patent: December 7, 1999Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Kiyoshi Morimoto, Yasushi Watanabe, Kimiaki Hayakawa, Sanji Tokuno
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Patent number: 4638642Abstract: A heat pump using water as a refrigerant comprises an evaporator equipped with a feedwater control device and a draining device, a compressor and a condenser equipped with a vacuum generating means.Type: GrantFiled: January 8, 1985Date of Patent: January 27, 1987Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventor: Sanji Tokuno