Patents by Inventor Sanjib K. Shrestha

Sanjib K. Shrestha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification of ebsulfur analogues with broad-spectrum antifungal activity
    Patent number: 10544112
    Abstract: The invention relates to novel ebsulfur analogues and novel pharmaceutical compositions comprising ebsulfur analogues. The invention also relates to novel methods of treating infections caused by fungal species comprising administration of ebselen, ebsulfur, and ebsulfur analogues.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: January 28, 2020
    Assignee: University of Kentucky Research Foundation
    Inventors: Sylvie Garneau-Tsodikova, Huy X. Ngo, Sanjib K. Shrestha
  • Identification of Ebsulfur Analogues with Broad-Spectrum Antifungal Activity
    Publication number: 20180282291
    Abstract: The invention relates to novel ebsulfur analogues and novel pharmaceutical compositions comprising ebsulfur analogues. The invention also relates to novel methods of treating infections caused by fungal species comprising administration of ebselen, ebsulfur, and ebsulfur analogues.
    Type: Application
    Filed: March 29, 2018
    Publication date: October 4, 2018
    Inventors: Sylvie GARNEAU-TSODIKOVA, Huy X. NGO, Sanjib K. SHRESTHA
  • Antifungal Compounds
    Publication number: 20180194742
    Abstract: Compounds and compositions having antifungal activity, and methods of using the antifungal compounds and compositions, are described for use in treating fungal infections.
    Type: Application
    Filed: December 8, 2017
    Publication date: July 12, 2018
    Inventors: Sylvie Garneau-Tsodikova, Sanjib K. Shrestha, Atefeh Garzan, Nishad Thamban Chandrika
  • Aminoglycoside and azole compositions and methods
    Patent number: 9669044
    Abstract: The present invention relates to novel fungicidal compound including an aminoglycoside analog having certain substituents at the 6 position of ring III that exhibit improved antifungal activity but possess minimal antibacterial properties in combination with fungicidal azoles. The aminoglycoside compounds are analogues of kanamycin A. Also provided are methods of synthesizing and methods of using the compounds of the present invention. The compounds of the present invention are useful in treating or preventing fungal disease.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: June 6, 2017
    Assignee: Utah State University
    Inventors: Jon Y. Takemoto, Cheng-wei Tom Chang, Sanjib K. Shrestha, Michelle Grilley
  • Aminoglycoside and Azole Compositions and Methods
    Publication number: 20140256665
    Abstract: The present invention relates to novel fungicidal compound including an aminoglycoside analog having certain substituents at the 6 position of ring III that exhibit improved antifungal activity but possess minimal antibacterial properties in combination with fungicidal azoles. The aminoglycoside compounds are analogues of kanamycin A. Also provided are methods of synthesizing and methods of using the compounds of the present invention. The compounds of the present invention are useful in treating or preventing fungal disease.
    Type: Application
    Filed: May 19, 2014
    Publication date: September 11, 2014
    Applicant: UTAH STATE UNIVERSITY
    Inventors: Jon Y. Takemoto, Cheng-wei Tom Chang, Sanjib K. Shrestha, Michelle Grilley