Patents by Inventor Sanju Sharma

Sanju Sharma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for treating abnormal cell growth related to unwanted guanine nucleotide exchange factor activity
    Publication number: 20030203464
    Abstract: Methods and compositions are described that affect the GTPase activity of members of the Ras superfamily, preferably Rac, such compositions include guanine nucleotide exchange factors that modulate the GTPase activity, preferably in the presence of GEF enhancers, exemplary guanine nucleotide exchange factors being Rac-GEF and Tiam-1, which are encoded by certain nucleic acid sequences that are herein described, along with uses for the guanine nucleotide exchange factors and the nucleic acid sequences including screening for ligands which recognize Rac-GEF, regulators of Rac-GEF activity, and methods of treating pathological conditions associated or related to a Ras superfamily GTPase, including Rac.
    Type: Application
    Filed: January 18, 2002
    Publication date: October 30, 2003
    Inventors: Gideon Bollag, Anne Crompton, Anne North, William Roscoe, Sanju Sharma
  • Methods and compositions for treating abnormal cell growth related to unwanted guanine nucleotide exchange factor activity
    Patent number: 6340575
    Abstract: Methods and compositions are described that affect the GTPase activity of members of the Ras superfamily, preferably Rac, such compositions include guanine nucleotide exchange factors that modulate the GTPase activity, preferably in the presence of GEF enhancers, exemplary guanine nucleotide exchange factors being Rac-GEF and Tiam-1, which are encoded by certain nucleic acid sequences that are herein described, along with uses for the guanine nucleotide exchange factors and the nucleic acid sequences including screening for ligands which recognize Rac-GEF, regulators of Rac-GEF activity, and methods of treating pathological conditions associated or related to a Ras superfamily GTPase, including Rac.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: January 22, 2002
    Assignee: Onyx Pharmaceuticals, Inc.
    Inventors: Gideon Bollag, Anne Crompton, Anne North, William Roscoe, Sanju Sharma