Patents by Inventor Sankar Reddy Budidet

Sankar Reddy Budidet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of angiotensin II antagonist
    Patent number: 7880015
    Abstract: The present invention provides a method for the preparation of N-(1-oxopentyl)-N-[[2?-(1H-tetra-zol-5-yl)[1,1?-biphenyl]-4-yl]methyl]-L-valine (Valsartan) which comprises; treating N-[[2?-(1-triphenylmethyl-tetra-zol-5-yl)biphenyl-4-yl]methyl]-L-valine methyl ester (X) with oxalic acid or its hydrates in a solvent to produce N-[[2?-(1-triph-enylmethyl-tetrazol-5-yl)biphenyl-4-yl]methy]-L-valine methyl ester oxalate (Xa) and treating the compound (Xa) with a base in a solvent followed by reacting with valeryl chloride in presence of base in a solvent to produce N-[[2?-(1-triphenylmethyl-tetra-zol-5-yl)[1,1?biphenyl]-4-yl]methyl]-N-valeryl-L-valine methyl ester (XI), de-protecting the compound (XI) using anhydrous acidic conditions to produce N-(1-oxopentyl)-N-[[2?-(1-H-tetrazol-5-yl)[1,1?biphenyl]-4-yl]methyl-L-valine methyl ester (V) followed by treating with base in a solvent to produce Valsartan.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: February 1, 2011
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sankar Reddy Budidet, Senthil Kumar Natarajan, Venkata Kishore Gowrabathina, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Amorphous 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol phosphate salt
    Publication number: 20100076047
    Abstract: The present invention relates to a novel amorphous form of 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol phosphate (Carvedilol dihydrogen phosphate) of Formula (I), and a process for the preparation thereof.
    Type: Application
    Filed: August 20, 2008
    Publication date: March 25, 2010
    Inventors: Sankar Reddy Budidet, Yallappa Somappa Somannavar, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process For the Preparation of Angiotensin II Antagonist
    Publication number: 20090281326
    Abstract: The present invention provides a method for the preparation of N-(1-oxopentyl)-N-[[2?-(1H-tetra-zol-5-yl)[1,1?-biphenyl]-4-yl]methyl]-L-valine (Valsartan) which comprises; treating N-[[2?-(1-triphenylmethyl-tetra-zol-5-yl)biphenyl-4-yl]methyl]-L-valine methyl ester (X) with oxalic acid or its hydrates in a solvent to produce N-[[2?-(1-triph-enylmethyl-tetrazol-5-yl)biphenyl-4-yl]methy]-L-valine methyl ester oxalate (Xa) and treating the compound (Xa) with a base in a solvent followed by reacting with valeryl chloride in presence of base in a solvent to produce N-[[2?-(1-triphenylmethyl-tetra-=zol-5-yl)[1,1?biphenyl]-4-yl]methyl]-N-valeryl-L-valine methyl ester (XI), de-protecting the compound (XI) using anhydrous acidic conditions to produce N-(1-oxopentyl)-N-[[2?-(1-H-tetrazol-5-yl)[1,1?biphenyl]-4-yl]methyl-L-valine methyl ester (V) followed by <treating with base in a solvent to produce Valsartan.
    Type: Application
    Filed: June 29, 2007
    Publication date: November 12, 2009
    Inventors: Sankar Reddy Budidet, Senthil Kumar Natarajan, Venkata Kishore Gowrabathina, Ramesh Dandala, Sivakumaran Meenakshisunderam