Abstract: The present invention relates to a method of adapting a composite signature of a phenotype. The method comprises the steps of providing for a composite signature of a phenotype with at least two different data types, which were respectively generated by two different modalities of measuring a specimen. Due to an adaption of one part of the signature of the phenotype the resulting adapted phenotype signature can be used as an input for a signature evaluation tool that was derived from data measured by a third modality of measurement.

Abstract: A system for x-ray fluoroscopic imaging of bodily tissue in which a scintillation screen and a charge coupled device (CCD) is used to accurately image selected tissue. An x-ray source generates x-rays which pass through a region of a subject's body, forming an x-ray image which reaches the scintillation screen. The scintillation screen re-radiates a spatial intensity pattern corresponding to the image, the pattern being detected by the CCD sensor. In a preferred embodiment the imager uses four 8×8-cm three-side buttable CCDs coupled to a CsI:T1 scintillator by straight (non-tapering) fiberoptics and tiled to achieve a field of view (FOV) of 16×16-cm at the image plane. Larger FOVs can be achieved by tiling more CCDs in a similar manner. The imaging system can be operated in a plurality of pixel pitch modes such as 78, 156 or 234-?m pixel pitch modes. The CCD sensor may also provide multi-resolution imaging.

Abstract: The present invention related to a system and method for performing scatter correction in x-ray imaging systems. A pixellated solid state imaging detector is used in which an electronic window or slot is scanned across the two dimensional surface of the detector to selectively record image data. In a preferred embodiment, a collimator is used to define relative movement between an x-ray beam and the x-ray detector. A scatter correction program can be used to correct for scattering in the detected image data to provide for improved imaging in medical, scientific and industrial applications.

Abstract: A system for x-ray fluoroscopic imaging of bodily tissue in which a scintillation screen and a charge coupled device (CCD) is used to accurately image selected tissue. An x-ray source generates x-rays which pass through a region of a subject's body, forming an x-ray image which reaches the scintillation screen. The scintillation screen re-radiates a spatial intensity pattern corresponding to the image, the pattern being detected by the CCD sensor. In a preferred embodiment the imager uses four 8×8-cm three-side buttable CCDs coupled to a CsI:T1 scintillator by straight (non-tapering) fiberoptics and tiled to achieve a field of view (FOV) of 16×16-cm at the image plane. Larger FOVs can be achieved by tiling more CCDs in a similar manner. The imaging system can be operated in a plurality of pixel pitch modes such as 78, 156 or 234-&mgr;m pixel pitch modes. The CCD sensor may also provide multi-resolution imaging.