Patents by Inventor Sankha Ghatak

Sankha Ghatak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED ENZYMES AND METHODS OF MAKING AND USING
    Publication number: 20230348865
    Abstract: The invention provides an engineered carboxylic acid reductase (CAR) enzyme, a nucleic acid encoding the CAR enzyme, and a non-naturally occurring microbial organism comprising an exogenous nucleic acid encoding the CAR, an engineered transaminase (TA) enzyme, and/or a hexamethylenediamine (HMD) transaminase (TA2) enzyme. The invention provides a non-naturally occurring microbial organism that has a 1,6-hexanediol (HDO) pathway with a HDO pathway enzyme expressed in sufficient amounts to produce 6 aminocaproate semi aldehyde, HDO, or both. The invention further provides a non-naturally occurring microbial organism that has an HMD pathway with a HMD pathway enzyme expressed in sufficient amounts to produce 6-aminocaproate semialdehyde, HMD, or both. The invention additionally provides bioderived HMD, 6-aminocaproate semialdehyde, and/or HDO and methods for producing bioderived HMD, 6-aminocaproate semialdehyde, and/or HDO.
    Type: Application
    Filed: April 23, 2021
    Publication date: November 2, 2023
    Inventors: Amit Mahendra SHAH, Deqiang ZHANG, Joseph Roy WARNER, Benjamin Matthew GRIFFIN, Russell Scott KOMOR, Harish NAGARAJAN, Sankha GHATAK, Toby Howard RICHARDSON
  • ENGINEERED CELLS FOR PRODUCTION OF CANNABINOIDS AND OTHER MALONYL-CoA-DERIVED PRODUCTS
    Publication number: 20230037234
    Abstract: The invention relates to engineered microorganisms (e.g., E. coli) and associated improvements for increasing the production cannabinoids (e.g. CBGA) or precursors or derivatives thereof.
    Type: Application
    Filed: November 25, 2020
    Publication date: February 2, 2023
    Inventors: Jingyi Li, Pierre DeWals, Andreas Schirmer, Sankha Ghatak, David Ryan Georgianna