Patents by Inventor Santanu Hati

Santanu Hati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for the prevention and treatment of hearing loss
    Patent number: 12070465
    Abstract: In one aspect, use of compounds as active agents to treat a hearing impairment and to prevent a hearing impairment, and methods of treating and/or preventing hearing impairments or disorders using the compositions are disclosed. (E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-S,6-dihydropyridin-2(1H)-one and derivatives exhibit excellent protection against antibiotic-induced hearing loss in zebrafish and mice. In one aspect, (E)-1-(3-(3,4,5-trimethoxy phenyl)acryloyl)-S,6-dihydropyridin-2(1H)-one and derivatives can be used as a therapy for the treatment and/or prevention of hearing loss. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: September 15, 2021
    Date of Patent: August 27, 2024
    Assignee: Ting Therapeutics LLC
    Inventors: Jian Zuo, Jeff North, Santanu Hati, Marisa Laura Zallocchi
  • Compositions, use, and method for CDK2-PROTACs for cancer therapy and hearing loss
    Patent number: 11744896
    Abstract: Provided are CDK2-PROTAC compounds and pharmaceutical compositions thereof that can be used for specific degradation of the cyclin-dependent kinase 2 (CDK2) protein, for treatment of cancers and other CDK2 related diseases as well as for prevention and treatment of hearing loss.
    Type: Grant
    Filed: September 28, 2021
    Date of Patent: September 5, 2023
    Assignees: CREIGHTON UNIVERSITY, ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (TENNESSEE NOT FOR PROFIT CORPORATION)
    Inventors: Jian Zuo, Santanu Hati, Marisa Laura Zallocchi, Robert Hazlitt, Jaeki Min
  • COMPOSITIONS, USE, AND METHOD FOR CDK2-PROTACS FOR CANCER THERAPY AND HEARING LOSS
    Publication number: 20220096642
    Abstract: Provided are CDK2-PROTAC compounds and pharmaceutical compositions thereof that can be used for specific degradation of the cyclin-dependent kinase 2 (CDK2) protein, for treatment of cancers and other CDK2 related diseases as well as for prevention and treatment of hearing loss.
    Type: Application
    Filed: September 28, 2021
    Publication date: March 31, 2022
    Inventors: Jian Zuo, Santanu Hati, Marisa Laura Zallocchi, Robert Hazlitt, Jaeki Min