Abstract: A device (1) for the depuration and sanitization of air comprising a tank (10) divided into at least two compartments (17-18) containing suitable liquids into which penetrate the lower parts of relative groups of perforated discs (21) arranged, suitably spaced one from the next, on a shaft (20), placed horizontally and set at its ends onto supports (131-141) obtained centrally on the transverse walls (13-14) which are at the extremities of the tank (10) and connected at one end to a geared electric motor (40). The upper parts of the perforated discs (21) are housed in a semicylindrical casing (30) in which they are traversed by the air drawn in by means of a fan (7). The liquids inserted into the compartments (17-18—etc.) of the tank (10) consist of a basic aqueous solution, with the addition of a surfactant and eventually antifoaming agents, to which can be added quaternary ammonium salts and/or organic salts whose adsorbing action allows also the sanitization of the treated air.