Abstract: The invention relates to chimeric vaccine antigens against hepatitis C virus (HCV) comprising selected regions of different antigens of said virus, which are placed in a pre-determined order inside the polypeptide. In addition, said chimeric antigens can include artificially formed specific epitopes for auxiliary T helper lymphocytes. The chimeric antigens and the resulting vaccine compositions are suitable for use in medicine and the pharmaceutical industry, as well as being suitable for prophylactic and/or therapeutic use against HCV. The vaccine compositions of the invention generate a powerful, broad-spectrum immune response against different antigens of the virus, with a minimum number of components.

Abstract: The invention relates to chimeric vaccine antigens against hepatitis C virus (HCV) comprising selected regions of different antigens of said virus, which are placed in a pre-determined order inside the polypeptide. In addition, said chimeric antigens can include artificially formed specific epitopes for auxiliary T helper lymphocytes. The chimeric antigens and the resulting vaccine compositions are suitable for use in medicine and the pharmaceutical industry, as well as being suitable for prophylactic and/or therapeutic use against HCV. The vaccine compositions of the invention generate a powerful, broad-spectrum immune response against different antigens of the virus, with a minimum number of components.

Abstract: A center console of a motor vehicle has a cover that is able to be opened, which closes a storage compartment that lies thereunder in its closed position and releases this in an open position. A comfortable adjustment of the cover is possible via an adjustment mechanism. The adjustment mechanism is formed in such a way that it first lifts the cover during opening and adjusts it backwards and subsequently swings it upwards.

Abstract: A center console of a motor vehicle has a cover that is able to be opened, which closes a storage compartment that lies thereunder in its closed position and releases this in an open position. A comfortable adjustment of the cover is possible via an adjustment mechanism. The adjustment mechanism is formed in such a way that it first lifts the cover during opening and adjusts it backwards and subsequently swings it upwards.

Abstract: Formulation of vaccine antigens, containing as main components: a—) one or several DNA expressing one or several proteins in the immunized individuals and b—) a viral antigen, in appropriate proportions. Development of new formulations, minimizing the number of components that enhance and diversify the spectrum of immune response against different pathogenic entities and generating combined vaccines against pathogens. These formulations can be applied in the pharmaceutical industry for preventive and-or therapeutic use in human.

Abstract: Formulation of vaccine antigens, containing as main components: a-) one or several DNA expressing one or several proteins in the immunized individuals and b-) a viral antigen, in appropriate proportions. Development of new formulations, minimizing the number of components that enhance and diversify the spectrum of immune response against different pathogenic entities and generating combined vaccines against pathogens. These formulations can be applied in the pharmaceutical industry for preventive and-or therapeutic use in human.

Abstract: A vaccine composition for the therapeutic and prophylactic treatment of Hepatitis C, containing as components the Hepatitis C virus structural proteins in certain proportions and having an enhancer effect in the development of the immune response against the Hepatitis C virus. Combined vaccines against pathogenic entities including this vaccine composition are also described.

Abstract: The present invention is related with the field of therapeutic vaccines against pathogens causing chronic diseases. It comprises the use in therapy of formulations containing the Hepatitis B surface antigen (HBsAg) as the main compound. The HBsAg is produced as a recombinant product in Picchia pastoris. The formulations of the present invention also comprise the combination of the Hepatitis B surface antigen and other coadministered antigens. The resulting formulations are able to generate potent lymphoprolipherative and cytotoxic responses apart from a remarkable response of specific antibodies, which make them very effective in the treatment of such diseases.

Abstract: Formulation of vaccine antigens, containing as main components: a-) one or several DNA expressing one or several proteins in the immunized individuals and b-) a viral antigen, in appropriate proportions. The novelty of the invention is given by the enhancing effect of at least one component on the immune response generated against the other one.

Abstract: A central console for a motor vehicle interior has a lower stowage compartment which can be closed by a lid module and is bounded laterally by side walls. The lid module can be pivoted about a pivot axis which is arranged at its rear end and runs in the transverse direction of the vehicle. An upper stowage compartment is arranged on the lower side of the lid module for accommodating a telephone device or other items and is covered by a first lid forming part of an armrest. A further upper stowage space is covered by a second lid which is designed as a further part of the armrest and can be pivoted about a pivot axis. The further upper stowage space is designed as part of the upper stowage compartment and together with the second lid is assigned to the lid module in such a manner that they can be pivoted together with the lid module.

Abstract: A central console for a motor vehicle interior has a lower stowage compartment which can be closed by a lid module and is bounded laterally by side walls. The lid module can be pivoted about a pivot axis which is arranged at its rear end and runs in the transverse direction of the vehicle. An upper stowage compartment is arranged on the lower side of the lid module for accommodating a telephone device or other items and is covered by a first lid forming part of an armrest. A further upper stowage space is covered by a second lid which is designed as a further part of the armrest and can be pivoted about a pivot axis. The further upper stowage space is designed as part of the upper stowage compartment and together with the second lid is assigned to the lid module in such a manner that they can be pivoted together with the lid module.

Abstract: A holding arrangement for the operating element of a telephone or a mobile telephone, such as a telephone receiver with a dialing keyboard or a handset, for an installation in a container existing in a vehicle is disclosed. A receiving device for releasably fixing the operating element and a holding body carrying the receiving device are provided. The holding body can be swivelled about a swivelling axis aligned transversely to its longitudinal course from a removed position with the operating element stored in the container into an offered position with the operating element situated to be easily gripped, and vice versa. For the purpose of a universal installation into all vehicle types in a space-saving manner, with a still remaining free useful space in the container, a fork-shaped carrier is provided for the swivel bearing of the holding body, which fork-shaped carrier accommodates the swivelling shaft in two carrying arms which project at a right angle from a carrying plate.

Abstract: A plate- or shell-like plastic trim panel is provided with a convex structure configured such that, in the event of a horizontal compressive load running essentially in the longitudinal direction of the vehicle, the trim panel undergoes a controlled elastic and/or plastic deformation in the direction of the adjoining free space. This arrangement avoids risking injury to legs of a vehicle occupant resulting from uncontrolled bending or breaking of flat trim panels without such convex structure.

Abstract: For the vertical alignment of a hinged covering flap, in particular of a glove-compartment cover, it is proposed to insert the hinge leaf on the cover side, accompanied by the spring-loaded engagement of teeth which protrude and engage into a row of teeth, into a channel fixedly disposed with respect to the vehicle body, and to secure the resulting alignment position with the use of a locking clip.

Abstract: A knee protection device in a motor vehicle having a dimensionally stable, cushioned and essentially plate-shaped load distributor which is supported on the end side by curved deformable holders on a cross member fixed to the vehicle. The energy absorption capacity of the two holders is fully utilized by spanning a reinforcement on the back side of the load distributor. The reinforcement has an approximately hat-shaped cross-section, extends at least near the holders and has outwardly projecting flanges which are connected with the load distributor.

Abstract: Motor vehicle instrument panel including a stiffening panel defining an instrument panel shape. The stiffening panel includes an airbag cover section and a hinge connection section which connects the airbag cover section to adjacent stiffening panel sections. A reinforcement mat is connected to a side of the stiffening panel which faces away from a vehicle passenger space bounded by the instrument panel when in an in-use position in a vehicle. The reinforcement mat includes a plurality of openings, and the reinforcement mat and stiffening panel are connected together by pressing of material of the stiffening panel into the openings of the reinforcement mat thereby providing an intimate connection of the reinforcement mat and stiffening panel without requiring additional fastening material.

Abstract: A cover sleeve for the protective covering of a clearance for the passage of a steering column of a motor vehicle through a dashboard is disclosed. To accommodate adjustment of the steering column as to its inclination and length, the cover sleeve is fastened by one end to the dashboard and by the other end to a steering column casing. The cover sleeve is braced between its fastening ends by a displaceable frame which is mounted on the casing and is acted upon in its direction of displacement by a resilient tensioning element.

Abstract: A glove box, for motor vehicles is arranged beneath the instrument panel, and is provided with a lid pivotably mounted on it about a horizontal axis. A closing device secures the lid to the glove box. To reduce the risk of injury to vehicle occupants which results from the closing device, a lock part of the closing device is arranged on the underside of the instrument panel with a latchbolt fastened inside a cavity on the inside of the lid and a latch which can be activated through a traction cable from a remote location is provided.