Patents by Inventor Santina QUARTA

Santina QUARTA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEW SYSTEM FOR THE TOPICAL PHARMACOLOGICAL RELEASE OF AN ACTIVE INGREDIENT
    Publication number: 20250099379
    Abstract: The present invention relates to the field of the formulation of bioactive compounds. More specifically, it relates to the use of wet silica-based polymers obtained with the sol-gel technology for the incorporation and prolonged release of an active ingredient, preferably of a protein for topical use, for example in the treatment of chronic ulcers and for the improvement of the trophism of skin appendages. The composition of the invention has several advantages, in particular it has a long permanence in the application point, by avoiding that the composition drips or dries up in contact with air.
    Type: Application
    Filed: January 18, 2023
    Publication date: March 27, 2025
    Applicant: UNIVERSITÀ DEGLI STUDI DI PADOVA
    Inventors: Patrizia PONTISSO, Margherita MORPURGO, Gian Paolo FADINI, Mattia ALBIERO, Alessandra BIASIOLO, Santina QUARTA, Mariagrazia RUVOLETTO, Cristian TURATO, Gianmarco VILLANO
  • Extracellular vesicles isolated from genetically modified cells over-expressing SERPINB3 for use in medicine
    Patent number: 12239667
    Abstract: The present invention concerns the therapeutic use of extracellular vesicles isolated from a genetically modified cell line over-expressing SerpinB3. In particular, said therapeutic use aimed at the treatment of acute pathologies characterized by ischemic or inflammatory tissue damage or by cell injury due to oxidative stress, such as cardiac, cerebral, intestinal, renal or limb ischaemia. Further examples of use consist of the preservation of transplant organs, including heart, lung, liver, bladder, pancreas and intestine. In a further aspect the invention relates to the use of a pharmaceutical composition comprising extracellular vesicles isolated from a genetically modified cell line over-expressing SerpinB3 and a pharmaceutically acceptable vehicle.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: March 4, 2025
    Assignee: UNIVERSITÀ DEGLI STUDI DI PADOVA
    Inventors: Patrizia Pontisso, Maurizio Muraca, Alessandra Biasiolo, Santina Quarta, Mariagrazia Ruvoletto, Gianmarco Villano
  • 1-piperidinepropionic acid for treating a fibrosing disease
    Patent number: 11628163
    Abstract: The present description relates to 1-piperidinepropionic acid or pharmaceutically acceptable salts thereof, or pharmaceutical compositions comprising it, for use in the treatment of chronic fibrosing diseases.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: April 18, 2023
    Assignee: Università degli Studi di Padova
    Inventors: Patrizia Pontisso, Alessandra Biasiolo, Andrea Cappon, Andrea Martini, Santina Quarta, Mariagrazia Ruvoletto, Cristian Turato, Gianmarco Villano
  • THE SERPINB3 INHIBITOR PIPERIDINPROPIONIC ACID FOR TUMOR TREATMENT
    Publication number: 20220265626
    Abstract: The invention concerns the use of 1-Piperidinpropionic acid or salts thereof, for the treatment of tumors that express SerpinB3.
    Type: Application
    Filed: July 23, 2020
    Publication date: August 25, 2022
    Applicant: UNIVERSITA' DEGLI STUDI DI PADOVA
    Inventors: Patrizia Pontisso, Alessandra Biasiolo, Andrea Martini, Santina Quarta, Mariagrazia Ruvoletto, Cristian Turato, Gianmarco Villano
  • EXTRACELLULAR VSICLES ISOLATED FROM GENETICALLY MODIFIED CELLS OVER-EXPRESSING SERPINB3 FOR USE IN MEDICINE
    Publication number: 20220143098
    Abstract: The present invention concerns the therapeutic use of extracellular vesicles isolated from a genetically modified cell line over-expressing SerpinB3. In particular, said therapeutic use aimed at the treatment of acute pathologies characterized by ischemic or inflammatory tissue damage or by cell injury due to oxidative stress, such as cardiac, cerebral, intestinal, renal or limb ischaemia. Further examples of use consist of the preservation of transplant organs, including heart, lung, liver, bladder, pancreas and intestine. In a further aspect the invention relates to the use of a pharmaceutical composition comprising extracellular vesicles isolated from a genetically modified cell line over-expressing SerpinB3 and a pharmaceutically acceptable vehicle.
    Type: Application
    Filed: February 14, 2020
    Publication date: May 12, 2022
    Inventors: Patrizia PONTISSO, Maurizio MURACA, Alessandra BIASIOLO, Santina QUARTA, Mariagrazia RUVOLETTO, Gianmarco VILLANO
  • 1-PIPERIDINEPROPIONIC ACID FOR TREATING A FIBROSING DISEASE
    Publication number: 20210137905
    Abstract: The present description relates to 1-piperidinepropionic acid or pharmaceutically acceptable salts thereof, or pharmaceutical compositions comprising it, for use in the treatment of chronic fibrosing diseases.
    Type: Application
    Filed: March 9, 2018
    Publication date: May 13, 2021
    Inventors: Patrizia PONTISSO, Alessandra BIASIOLO, Andrea CAPPON, Andrea MARTINI, Santina QUARTA, Mariagrazia RUVOLETTO, Cristian TURATO, Gianmarco VILLANO