Patents by Inventor Santosh C. Sinha

Santosh C. Sinha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective Alpha 2B/2C Agonists
    Publication number: 20110028523
    Abstract: Described herein are compounds useful as agonists of alpha 2B/2C receptors. Pharmaceutical compositions including the presently described compounds and methods of treatment of diseases and conditions with the presently described compounds also are disclosed.
    Type: Application
    Filed: July 1, 2010
    Publication date: February 3, 2011
    Applicant: ALLERGAN, INC.
    Inventors: Phong X. Nguyen, Ken Chow, Todd M. Heidelbaugh, Dario G. Gomez, Wenkui K. Fang, Santosh C. Sinha, Michael E. Garst, Daniel W. Gil
  • ((PHENYL)IMIDAZOLYL)METHYLHETEROARYL COMPOUNDS
    Publication number: 20100273814
    Abstract: Disclosed herein is a compound of the formula wherein A and B are described herein. Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Application
    Filed: May 13, 2008
    Publication date: October 28, 2010
    Inventors: Santosh C. Sinha, Todd M. Heidelbaugh, Ken Chow, Smita S. Bhat, Phong X. Nguyen, Michael E. Garst
  • THERAPEUTIC ((PHENYL)IMIDAZOLYL)METHYLQUINOLINYL COMPOUNDS
    Publication number: 20100197729
    Abstract: Disclosed herein is a compound of the formula (I) therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Application
    Filed: May 21, 2008
    Publication date: August 5, 2010
    Applicant: ALLERDAN, INC.
    Inventors: Santosh C. Sinha, Todd M. Heidelbaugh, Ken Chow, Smita S. Bhat, Michael E. Garst
  • Therapeutic ((Bicylicheteroaryl)Imidazolyl) Methylheteroaryl Compounds
    Publication number: 20100190823
    Abstract: Disclosed herein is a compound of the formula (I) therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Application
    Filed: May 21, 2008
    Publication date: July 29, 2010
    Applicant: ALLEGERGAN INC.
    Inventors: Santosh C. Sinha, Todd M. Heidelbaugh, Ken Chow, Smita S. Bhat, Phong X. Nguyen, Michael E. Garst
  • N-(1-PHENYL-2-ARYLETHYL)-4,5-DIHYDRO-2H-PYRROL-5-AMINE COMPOUNDS AS SUBTYPE SELECTIVE MODULATORS OF ALPHA2B OR ALPHA2B AND ALPHA2C ADRENOCEPTORS
    Publication number: 20100145061
    Abstract: The present invention provides compounds which are N-(1-phenyl-2-arylethyl)-4,5-dihydro-2H-pyrrol-5-amine compounds and are subtype selective modulators of alpha 2B or alpha 2B and alpha 2C adrenoreceptors and are selected from the group of compounds represented by the formula
    Type: Application
    Filed: December 7, 2009
    Publication date: June 10, 2010
    Applicant: ALLERGAN, INC.
    Inventors: Ken Chow, Janet A. Takeuchi, Ling Li, Todd M. Heidelbaugh, Phong X. Nguyen, Evelyn G. Corpuz, Wenkui K. Fang, Santosh C. Sinha, Michael E. Garst
  • THERAPEUTICALLY USEFUL SUBSTITUTED HYDROPYRIDO [3,2,1-ij] QUINOLINE COMPOUNDS
    Publication number: 20100009985
    Abstract: Disclosed herein are compounds represented by the structural formula: therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Application
    Filed: May 7, 2009
    Publication date: January 14, 2010
    Applicant: ALLERGAN, INC.
    Inventors: Santosh C. SINHA, Smita S. BHAT, Ken CHOW, Richard L. BEARD, John E. DONELLO, Michael E. GARST
  • METHODS OF TREATING ALPHA ADRENERGIC MEDIATED CONDITIONS
    Publication number: 20090306398
    Abstract: Described herein are compounds for and methods of treating conditions or diseases in a subject by administering to the subject a pharmaceutical composition containing an effective amount of an ?-adrenergic modulator. The compounds and methods are also useful for alleviating types of pain, both acute and chronic.
    Type: Application
    Filed: June 5, 2009
    Publication date: December 10, 2009
    Applicant: ALLERGAN, INC.
    Inventors: Wenkui K. Fang, Phong X. Nguyen, Ken Chow, Todd M. Heidelbaugh, Dario G. Gomez, Michael E. Garst, Santosh C. Sinha
  • METHODS OF TREATING ALPHA ADRENERGIC MEDIATED CONDITIONS
    Publication number: 20090306161
    Abstract: Described herein are compounds for and methods of treating conditions or diseases in a subject by administering to the subject a pharmaceutical composition containing an effective amount of an ?-adrenergic modulator. The compounds and methods are also useful for alleviating types of pain, both acute and chronic.
    Type: Application
    Filed: June 5, 2009
    Publication date: December 10, 2009
    Applicant: ALLERGAN, INC.
    Inventors: Wenkui K. Fang, Phong X. Nguyen, Ken Chow, Todd M. Heidelbaugh, Dario G. Gomez, Michael E. Garst, Santosh C. Sinha
  • THERAPEUTICALLY USEFUL SUBSTITUTED 1,7-DIPHENYL-1,2,3,5,6,7-HEXAHYDROPYRIDO[3,2,1-Ij]QUINOLINE COMPOUNDS
    Publication number: 20090281322
    Abstract: Disclosed herein are compounds represented by the structural formula: Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Application
    Filed: May 1, 2009
    Publication date: November 12, 2009
    Applicant: ALLERGAN, INC.
    Inventors: Santosh C. Sinha, Smita S. Bhat, Ken Chow, Richard L. Beard, John E. Donello
  • SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF
    Publication number: 20090197898
    Abstract: The invention provides well-defined heterocyclic compounds that are useful as subtype selective alpha 2 adrenergic agonists. As such, the compounds described herein are useful in treating a wide variety of disorders associated with selective subtype modulation of alpha 2 adrenergic receptors.
    Type: Application
    Filed: January 14, 2009
    Publication date: August 6, 2009
    Inventors: Todd M. Heidelbaugh, Ken Chow, Santosh C. Sinha, Phong X. Nguyen, Ling Li, Wenkui K. Fang, Janet A. Takeuchi, Smita Bhat
  • ALPHA 2 ADRENERGIC AGONISTS
    Publication number: 20090182026
    Abstract: A compound is disclosed herein comprising or a pharmaceutically acceptable salt, metabolite, or prodrug thereof; wherein R1, R2, and R3 are independently hydrogen or C1-4 alkyl; A is OH, NH2, or SH; and n is 0, 1, or 2. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Application
    Filed: June 6, 2006
    Publication date: July 16, 2009
    Applicant: ALLERGAN, INC.
    Inventors: Ken Chow, Todd M. Heidelbaugh, Phong X. Nguyen, Santosh C. Sinha
  • SUBSTITUTED-ARYL-2-PHENYLETHYL-1H-IMIDAZOLE COMPOUNDS AS SUBTYPE SELECTIVE MODULATORS OF ALPHA 2B AND/OR ALPHA 2C ADRENERGIC RECEPTORS
    Publication number: 20090176843
    Abstract: A compound having selective modulating activity at the alpha 2B and/or alpha 2C adrenergic receptor subtypes is represented by the general Formula 1: wherein n=1-4; X is C or N; R1—R6 can be the same or different and are independently selected from the group consisting of H, C1-6 alkyl, OCH3, OH, F, Cl, Br, CH2OH, CH2N(R7)2, C(O)R8, CH2CN, CF3; wherein R7 is H or C1-6 alkyl; and R8 is C1-6 alkyl or aryl. The compounds of Formula 1 can be incorporated in pharmaceutical compositions and used in methods of treatment of alpha 2 receptor mediated diseases and conditions.
    Type: Application
    Filed: January 9, 2008
    Publication date: July 9, 2009
    Inventors: Santosh C. Sinha, Todd M. Heidelbaugh, Smita S. Bhat, Ken Chow, Michael E. Garst
  • 7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity
    Patent number: 6887896
    Abstract: Compounds of the formula where the variations have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effects of transiently increasing triglyceride levels and reducing serum thyroxine levels.
    Type: Grant
    Filed: October 29, 2003
    Date of Patent: May 3, 2005
    Assignee: Allergan, Inc.
    Inventors: Richard L. Beard, Tien T. Duong, Janet A. Takeuchi, Ling Li, Kwok Yin Tsang, Xiaoxia Liu, Jayasree Vasudevan, Liming Wang, Santosh C. Sinha, Haiqing Yuan, Roshantha A. Chandraratna