Patents by Inventor Santosh Kumar Kotturi Rajaiah

Santosh Kumar Kotturi Rajaiah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fused pyrimidine compounds as BRD4 and JAK2 dual inhibitors and methods for use thereof
    Patent number: 11279703
    Abstract: The present invention relates to fused pyrimidine compounds, particularly pyrrolopyrimidine and thienopyrimidine compounds and derivatives thereof, pharmaceutical compositions thereof, and methods of inhibiting BRD4 and/or JAK2, as well as methods of treating various diseases and conditions, such as cancer and leukemia, with such compounds. Bromodomain binding and JAK activity are included.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: March 22, 2022
    Assignee: APTOSE BIOSCIENCES INC.
    Inventors: Ram Shankar Upadhayaya, Raghava Kethiri, Sachin Madan, Santosh Kumar Kotturi Rajaiah
  • FUSED PYRIMIDINE COMPOUNDS AS BRD4 AND JAK2 DUAL INHIBITORS AND METHODS FOR USE THEREOF
    Publication number: 20200095252
    Abstract: The present invention relates to fused pyrimidine compounds, particularly pyrrolopyrimidine and thienopyrimidine compounds and derivatives thereof, pharmaceutical compositions thereof, and methods of inhibiting BRD4 and/or JAK2, as well as methods of treating various diseases and conditions, such as cancer and leukemia, with such compounds. Bromodomain binding and JAK activity are included.
    Type: Application
    Filed: December 1, 2017
    Publication date: March 26, 2020
    Applicant: APTOSE BIOSCIENCES INC.
    Inventors: Ram Shankar Upadhayaya, Raghava Kethiri, Sachin Madan, Santosh Kumar Kotturi Rajaiah