Patents by Inventor Santosh Kumar Rai

Santosh Kumar Rai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS
    Publication number: 20220332700
    Abstract: The present invention relates to inhibitors of apoptosis signal-regulating kinase 1 (“ASK1”), a process for synthesis of the compounds of the present invention, composition comprising the compounds and use of the compounds for inhibition of ASK1.
    Type: Application
    Filed: June 24, 2020
    Publication date: October 20, 2022
    Applicant: MANKIND PHARMA LTD
    Inventors: Santosh Kumar RAI, Rakesh Iswar PATIL, Somnath Singha ROY, Kalicharan SHARMA, Rahul DWIVEDI, Srinivasa Reddy BAPURAM, Anil KUMAR
  • COMBINATION THERAPY OF GPR119 AGONISTS AND DPP-4 INHIBITORS
    Publication number: 20220265652
    Abstract: The present invention relates to combinations of GPR119 receptor agonists with DPP-4 inhibitors and their use thereof for treating or preventing cardiovascular and metabolic disorders, including diabetes mellitus, non-alcoholic fatty liver disease (NAFLD), NAFL, NASH, dyslipidemia, and related disorders thereto.
    Type: Application
    Filed: June 23, 2020
    Publication date: August 25, 2022
    Inventors: Rakesh Iswar PATIL, Sazid ALI, Srinivasa Reddy BAPURAM, Santosh Kumar RAI, Anil KUMAR
  • NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1
    Publication number: 20220235046
    Abstract: An object of the invention is to provide compounds as selective JAK1 inhibitor, a process for preparation of the inhibitors, a composition containing the compounds and utility of the compounds.
    Type: Application
    Filed: May 26, 2020
    Publication date: July 28, 2022
    Applicant: MANKIND PHARMA LTD.
    Inventors: Santosh Kumar RAI, Mahadev BANDGAR, Sazid ALI, Himanshu RAI, Amol Pandurang GUNJAL, Rakesh Iswar PATIL, Srinivasa Reddy BAPURAM, Anil KUMAR
  • GPR119 agonist compounds
    Patent number: 10954229
    Abstract: The present invention relates to novel compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: March 23, 2021
    Assignee: MANKIND PHARMA LTD.
    Inventors: Rakesh Ishwar Patil, Jeevan Verma, Puneet Kumar, Amol Pandurang Gunjal, Himanshu Rai, Santosh Kumar Rai, Anil Kumar
  • Compounds as GPR119 agonists
    Patent number: 10919915
    Abstract: The present invention relates to novel compounds of formula (I) as GPR119 agonist, composition compositions containing such compounds and method of preparation thereof.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: February 16, 2021
    Assignee: MANKIND PHARMA LTD.
    Inventors: Rakesh Ishwar Patil, Jeevan Verma, Dharmesh Shah, Sazid Ali, Srinivasa Reddy Bapuram, Santosh Kumar Rai, Anil Kumar
  • NOVEL GPR119 AGONIST COMPOUNDS
    Publication number: 20200317661
    Abstract: The present invention relates to novel compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Application
    Filed: June 23, 2020
    Publication date: October 8, 2020
    Inventors: Rakesh Ishwar Patil, Jeevan Verma, Puneet Kumar, Amol Pandurang Gunjal, Himanshu Rai, Santosh Kumar Rai, Anil Kumar
  • GPR119 agonist compounds
    Patent number: 10752622
    Abstract: The present invention relates to novel compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Grant
    Filed: December 24, 2018
    Date of Patent: August 25, 2020
    Assignee: MANKIND PHARMA LTD.
    Inventors: Rakesh Ishwar Patil, Jeevan Verma, Puneet Kumar, Amol Pandurang Gunjal, Himanshu Rai, Santosh Kumar Rai, Anil Kumar
  • NOVEL COMPOUNDS AS GPR119 AGONISTS
    Publication number: 20200040006
    Abstract: The present invention relates to novel compounds of formula (I) as GPR119 agonist, composition compositions containing such compounds and method of preparation thereof.
    Type: Application
    Filed: October 14, 2019
    Publication date: February 6, 2020
    Inventors: Rakesh Ishwar Patil, Jeevan Verma, Dharmesh Shah, Sazid Ali, Srinivasa Reddy Bapuram, Santosh Kumar Rai, Anil Kumar
  • Compounds as GPR119 agonists
    Patent number: 10526345
    Abstract: The present invention relates to novel compounds of formula (I) as GPR119 agonist, composition compositions containing such compounds and method of preparation thereof.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: January 7, 2020
    Assignee: MANKIND PHARMA LTD.
    Inventors: Rakesh Ishwar Patil, Jeevan Verma, Dharmesh Shah, Sazid Ali, Srinivasa Reddy Bapuram, Santosh Kumar Rai, Anil Kumar
  • NOVEL GPR119 AGONIST COMPOUNDS
    Publication number: 20190127363
    Abstract: The present invention relates to novel compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Application
    Filed: December 24, 2018
    Publication date: May 2, 2019
    Inventors: Rakesh Ishwar Patil, Jeevan Verma, Puneet Kumar, Amol Pandurang Gunjal, Himanshu Rai, Santosh Kumar Rai, Anil Kumar
  • Compounds as anti-tubercular agents
    Patent number: 10207993
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: February 19, 2019
    Assignees: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep Dugar, Dinesh Mahajan, Santosh Kumar Rai, Kanury Rao, Varshneya Singh
  • GPR119 agonist compounds
    Patent number: 10208030
    Abstract: The present invention relates to novel compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: February 19, 2019
    Assignee: Mankind Pharma Ltd.
    Inventors: Rakesh Ishwar Patil, Jeevan Verma, Puneet Kumar, Amol Pandurang Gunjal, Himanshu Rai, Santosh Kumar Rai, Anil Kumar
  • Compounds as anti-tubercular agents
    Patent number: 10100012
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: October 16, 2018
    Assignees: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep Dugar, Dinesh Mahajan, Santosh Kumar Rai, Kanury Rao, Varshneya Singh
  • NOVEL COMPOUNDS AS ANTI-TUBERCULAR AGENTS
    Publication number: 20170334851
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Application
    Filed: August 10, 2017
    Publication date: November 23, 2017
    Applicants: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, Santosh Kumar RAI, Kanury RAO, Varshneya SINGH
  • NOVEL GPR119 AGONIST COMPOUNDS
    Publication number: 20170291894
    Abstract: The present invention relates to novel compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Application
    Filed: April 4, 2017
    Publication date: October 12, 2017
    Inventors: Rakesh Ishwar Patil, Jeevan Verma, Puneet Kumar, Amol Pandurang Gunjal, Himanshu Rai, Santosh Kumar Rai, Anil Kumar
  • NOVEL COMPOUNDS AS GPR119 AGONISTS
    Publication number: 20170291910
    Abstract: The present invention relates to novel compounds of formula (I) as GPR119 agonist, composition compositions containing such compounds and method of preparation thereof.
    Type: Application
    Filed: April 4, 2017
    Publication date: October 12, 2017
    Inventors: Rakesh Ishwar Patil, Jeevan Verma, Dharmesh Shah, Sazid Ali, Srinivasa Reddy Bapuram, Santosh Kumar Rai, Anil Kumar
  • NOVEL COMPOUNDS AS ANTI-TUBERCULAR AGENTS
    Publication number: 20170183305
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Application
    Filed: June 1, 2015
    Publication date: June 29, 2017
    Applicants: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, Santosh Kumar RAI, Kanury RAO, Varshneya SINGH
  • NOVEL AUTOTETRAPLOID CLONE 'CIMAP-KHUS 40' OF VETIVER (VETIVERIA ZIZANIODES) USEFUL FOR CARBON SEQUESTRATION AND SOIL CONSERVATION
    Publication number: 20120278945
    Abstract: The present invention relates to the development of a novel clone of Vetiver [Vetveria zizaniodes (L) Nash. syn. Chrysopogon zizaniodes (L.) Roberty; family Poaceae], named ‘CIMAP-KHUS 40’ characterised by somatic chromosome number 4x=40, larger stomata, fast growing deep penetrating roots, and seed infertility disabling its spread as a weed. This clone has unique ISSR and RAPD profiles that serve as DNA-fingerprints, and is developed from a unique diploid plant (2n=20). The invention document details all the pertinent data relating to this clone, its biological features and usefulness, and the method of its development.
    Type: Application
    Filed: April 30, 2012
    Publication date: November 1, 2012
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Umesh Chandra Lavania, Santosh Kumar Rai, Seshu Lavania, Surochita Basu, Basant Kumar Dubey, Ram Ujagir
  • Autotetraploid plant useful for carbon sequestration and soil conservation named ‘CIMAP-KH 40’
    Patent number: PP26474
    Abstract: The present invention relates to the development of a novel clone of Vetiver [Vetveria zizaniodes (L) Nash. syn. Chrysopogon zizaniodes (L.) Roberty; family Poaceae], named ‘CIMAP-KHUS 40’ characterised by somatic chromosome number 4x=40, larger stomata, fast growing deep penetrating roots, and seed infertility disabling its spread as a weed. This clone has unique ISSR and RAPD profiles that serve as DNA-fingerprints, and is developed from a unique diploid plant (2n=20). The invention document details all the pertinent data relating to this clone, its biological features and usefulness, and the method of its development.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: March 8, 2016
    Assignee: Council of Scientific and Industrial Research
    Inventors: Umesh Chandra Lavania, Santosh Kumar Rai, Seshu Lavania, Surochita Basu, Basant Kumar Dubey, Ram Ujagir