Abstract: In some aspects, the techniques described herein relate to a method including: receiving, by a capture module, a reception notification from an email server, wherein the reception notification is triggered by an event handler of the email server and the event handler is configured to generate the reception notification upon receipt of an email in a mailbox of the email server; generating, by the capture module, a reception event including metadata related to the email that is received at the mailbox of the email server; sending, by the capture module, the reception event to an event streaming platform; retrieving, by a workflow engine, email metadata, wherein the email metadata is related to the email that is received at the mailbox of the email server; and providing, by the workflow engine and as input to a rules-based procedure, the email metadata.

Abstract: Systems and methods for support server high availability with network link bonding for cloud overlay networks are disclosed herein. The method can include selecting a compute instance, identifying a plurality of Network Virtualization Devices (“NVD”) for association with the compute instance, and creating a number of Virtualized Network Interface Cards (“VNIC”), each of which VNICs can reside in one of the plurality of NVDs. The method can include overlaying an IP address of the compute instance to each of the VNICs, such that each of the VNICs share a common IP address, designating a network path formed by one of the VNICs in one of the NVDs as an active network path and another of the network paths as an inactive network path, and activating the inactive network path when the active network path fails.

Abstract: The present disclosure provides methods of producing iPSCs comprising contacting a cell (e.g., CD34+ cell or other blood cell) in suspension with one or more circular RNAs encoding one or more reprogramming factors and maintaining the cell under conditions under which a reprogrammed iPSC is obtained. In some embodiments, the circular RNA encodes a reprogramming factor (selected from Oct3/4, Klf4, Sox2, Nanog, Lin28, c-Myc, or L-Myc, or a fragment or variant thereof.

Abstract: Techniques and apparatus for data networking are described. In one example, a method of queuing Remote Direct Memory Access (RDMA) packets includes receiving a first RDMA packet having a first quality-of-service (QOS) data field; based on a value of the first QoS data field, queueing the first RDMA packet in a first queue of a plurality of queues; receiving a second RDMA packet having a second QoS data field; and based on a value of the second QoS data field, queueing the second RDMA packet in a second queue of the plurality of the queues, the second queue being different than the first queue.

Abstract: One or more devices, systems, methods and storage mediums for performing medical procedure (e.g., needle guidance, ablation, biopsy, etc.) planning and/or performance, and/or for performing registration using at least one mask, are provided. Examples of applications for such devices, systems, methods and storage mediums include imaging, evaluating and diagnosing biological objects, such as, but not limited to, lesions and tumors, and such devices, systems, methods and storage mediums may be used for radiotherapy applications (e.g., to determine whether to place seed(s) for radiotherapy). The devices, systems, methods and storage mediums provide improved registration results by utilizing at least one mask to suppress one or more artifacts or objects (which may or may not include, but is not limited to, at least one medical instrument or tool) in an image including a portion of the medical guidance device and/or to enhance a region or target of interest in the image.

Abstract: Techniques and apparatus for data networking are described. In one example, a method includes receiving a first Layer-2 Remote Direct Memory Access (RDMA) packet which includes a virtual local area network (VLAN) tag and a quality-of-service (QoS) data field; converting the first Layer-2 RDMA packet to a first Layer-3 encapsulated packet; and forwarding the first Layer-3 encapsulated packet to a switch fabric. In this method, the converting includes adding at least one header to the first Layer-2 RDMA packet, where the at least one header includes: a virtual network identifier that is based on information from the VLAN tag, and a QoS value that is based on information from the QoS data field.

Abstract: Techniques for controlling packet flows through the generation of packet flow rules are described. In an example, a network virtualization device receives network data. The network virtualization device determines a set of networks of a virtual network based on the network data. The network virtualization device receives flow data of the customer. The network virtualization device generates a packet flow rule based on the flow data and the set of networks. The packet flow rule defines a network boundary of one or more networks such that a first packet having a destination within the network boundary can flow and such that a second packet having a destination outside of the network boundary is to be dropped. The network virtualization device stores the packet flow rule in association with the compute instance.

Abstract: One or more devices, systems, methods and storage mediums for performing medical procedure (e.g., needle guidance, ablation, biopsy, etc.) planning and/or performance, and/or for performing registration using at least one mask, are provided. Examples of applications for such devices, systems, methods and storage mediums include imaging, evaluating and diagnosing biological objects, such as, but not limited to, lesions and tumors, and such devices, systems, methods and storage mediums may be used for radiotherapy applications (e.g., to determine whether to place seed(s) for radiotherapy). The devices, systems, methods and storage mediums provide improved registration results by utilizing at least one mask to suppress one or more artifacts or objects (which may or may not include, but is not limited to, at least one medical instrument or tool) in an image including a portion of the medical guidance device and/or to enhance a region or target of interest in the image.

Abstract: Techniques and apparatus for data networking are described. In one example, a method of queuing Remote Direct Memory Access (RDMA) packets includes receiving a first RDMA packet having a first quality-of-service (QoS) data field; based on a value of the first QoS data field, queueing the first RDMA packet in a first queue of a plurality of queues; receiving a second RDMA packet having a second QoS data field; and based on a value of the second QoS data field, queueing the second RDMA packet in a second queue of the plurality of the queues, the second queue being different than the first queue.

Abstract: Techniques and apparatus for data networking are described. In one example, a method includes receiving a first Layer-2 Remote Direct Memory Access (RDMA) packet which includes a virtual local area network (VLAN) tag and a quality-of-service (QoS) data field; converting the first Layer-2 RDMA packet to a first Layer-3 encapsulated packet; and forwarding the first Layer-3 encapsulated packet to a switch fabric. In this method, the converting includes adding at least one header to the first Layer-2 RDMA packet, where the at least one header includes: a virtual network identifier that is based on information from the VLAN tag, and a QoS value that is based on information from the QoS data field.

Abstract: Discussed herein is a framework that provisions for customized processing for different classes of traffic. A network device in a communication path between a source host machine and a destination host machine extracts a tag from a packet received by the network device. The packet originates at a source executing on the source host machine and whose destination is the destination host machine. The tag set by the source and indicative of a first traffic class to be associated with the packet, the first traffic class being selected by the source from a plurality of traffic classes. The network device determines, based on the tag, that the first traffic class corresponds to a latency sensitive traffic and processes the packet using one or more settings configured at the network device for processing packets associated with the first traffic class.

Abstract: Systems and methods for highly-available host networking with active-active or active-backup traffic load-balancing are disclosed herein. The method can include selecting a compute instance from an overlay network residing on a substrate network, identifying a plurality of Network Virtualization Devices (“NVD”) for association with the compute instance, creating a loopback interface on each of the NVDs, each of which loopback interfaces can include a shared IP address that can be in the substrate layer, prepopulating a table in each of the NVDs, the table linking the shared IP address to the compute instance, and each of the plurality of NVDs advertising a unique route to the compute instance via the shared IP address.

Abstract: A device to image registration method includes obtaining image data of a device, the device including a plurality of fiducials arranged as a fiducial frame on the device; detecting fiducial objects within the image data; cropping the image data to generate cropped image data; applying a feature enhancement to the cropped image data to enhance the fiducial objects; generating a candidate list of candidate objects based on the feature enhancement, and determining a common plane based on at least three points in the candidate list; determining a representative point for each candidate object; determining outlier candidate objects based on the common plane; determining resultant objects by extracting the outlier candidate objects from the candidate list; and registering the resultant objects to the device by matching the representative points of the resultant objects with a model of the fiducial frame.

Abstract: Systems and methods for highly-available host networking with active-active or active-backup traffic load-balancing are disclosed herein. The method can include selecting a compute instance from an overlay network residing on a substrate network, identifying a plurality of Network Virtualization Devices (“NVD”) for association with the compute instance, creating a loopback interface on each of the NVDs, each of which loopback interfaces can include a shared IP address that can be in the substrate layer, prepopulating a table in each of the NVDs, the table linking the shared IP address to the compute instance, and each of the plurality of NVDs advertising a unique route to the compute instance via the shared IP address.

Abstract: Discussed herein is a framework that provisions for customized processing for different classes of traffic. A network device in a communication path between a source host machine and a destination host machine extracts a tag from a packet received by the network device. The packet originates at a source executing on the source host machine and whose destination is the destination host machine. The tag set by the source and indicative of a first traffic class to be associated with the packet, the first traffic class being selected by the source from a plurality of traffic classes. The network device determines, based on the tag, that the first traffic class corresponds to a bandwidth sensitive traffic and processes the packet using one or more settings configured at the network device for processing packets associated with the first traffic class.

Abstract: Discussed herein is a framework that provisions for customized processing for different classes of traffic. A network device in a communication path between a source host machine and 5 a destination host machine extracts a tag from a packet received by the network device. The packet originates at a source executing on the source host machine and whose destination is the destination host machine. The tag set by the source and indicative of a first traffic class to be associated with the packet, the first traffic class being selected by the source from a plurality of traffic classes. The network device determines the first traffic class based on the tag extracted from the packet and 10 processes the packet based on the first traffic class.

Abstract: Provided herein are recombinant circular RNAs comprising at least one protein-coding nucleic acid sequence, wherein the protein-coding nucleic acid sequence encodes a reprogramming factor (e.g., a transcription factor), wherein the reprogramming factor is Oct3/4, Klf4, Sox2, Nanog, Lin28, c-Myc, or L-Myc, or a fragment or variant thereof. Also provided herein are methods of producing induced pluripotent stem cells (iPSC), the method comprising contacting a somatic cell with at least one of the recombinant circular RNAs described herein and maintaining the cell under conditions under which a reprogrammed iPSC is obtained.

Abstract: Systems and methods for transparent high availability for multi-customer support with hypervisor based bond implementation. The method can include creating a network path bond between a plurality of compute instances and a plurality of Network Virtualization Devices (“NVD”), the network path bond comprising a plurality of network paths, identifying a monitoring bond coupling the plurality of NVDs to a monitoring agent, creating a number of monitoring VNICs, each of the number of monitoring VNICs residing in one of the plurality of NVDs, overlaying a unique IP address to each of the monitoring VNICs, determining with the monitoring agent a health of at least one of network paths, the network paths including an active network path and an inactive network path, and activating the inactive network path when the active network path fails.

Abstract: Techniques for controlling packet flows through the generation of packet flow rules are described. In an example, a network virtualization device receives network data. The network virtualization device determines a set of networks of a virtual network based on the network data. The network virtualization device receives flow data of the customer. The network virtualization device generates a packet flow rule based on the flow data and the set of networks. The packet flow rule defines a network boundary of one or more networks such that a first packet having a destination within the network boundary can flow and such that a second packet having a destination outside of the network boundary is to be dropped. The network virtualization device stores the packet flow rule in association with the compute instance.

Abstract: Techniques for controlling packet flows are described. In an example, a packet is sent on a virtual network. The packet’s header includes scoping data that indicates a network boundary within which the packet is permitted and/or prohibited to flow. A network virtualization device of a substrate network receives the packet. The network virtualization device determines the scoping data from the header and, based on network configuration information, determines the forward flow of the packet. If the forward flow falls within a permitted network boundary indicated by the scoping data, the network virtualization device sends the packet forward. Otherwise, the packet is dropped.