Patents by Inventor Santtu Ollila
Santtu Ollila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240001146Abstract: A method of determining treatment geometries for a radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs); defining a delivery coordinate space (DCS); for each beam's eye view (BEV) plane of each vertex in the DCS, and for each ROI, evaluating a dose of the ROI using transport solutions; evaluating a BEV scores of each pixel of the BEV plane using the doses of the one or more ROIs; determining one or more BEV regions in the BEV plane based on the BEV scores; determining a BEV region connectivity manifold based on the BEV regions; determining a set of treatment trajectories based on the BEV region connectivity manifold; and determining one or more IMRT fields. Each treatment trajectory defines a path through a set of vertices in the DCS. Each IMRT field defines a direction of incidence corresponding to a vertex in the DCS.Type: ApplicationFiled: September 8, 2023Publication date: January 4, 2024Inventor: Santtu Ollila
-
Publication number: 20230338748Abstract: A method of beam angle optimization for an IMRT radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs), defining a delivery coordinate space (DCS), for each ROI, solving an adjoint transport to obtain an adjoint solution field from the ROI, for each vertex in the DCS, evaluating an adjoint photon fluence by performing ray tracing of the adjoint solution field, evaluating a dose of the ROI using the adjoint photon fluence, for each vertex in the DCS, evaluating a respective beam's eye view (BEV) score of each pixel of a BEV plane using the doses of the one or more ROIs, determining one or more BEV regions in the BEV plane based on the BEV scores, determining a BEV region connectivity manifold based on the BEV regions, and determining a set of IMRT fields based on the BEV region connectivity manifold.Type: ApplicationFiled: June 27, 2023Publication date: October 26, 2023Inventors: Santtu Ollila, Todd Arlin Wareing, John Morton McGhee, Douglas Allen Barnett, JR., Alexander Enrique Maslowski
-
Patent number: 11771921Abstract: A method of determining treatment geometries for a radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs); defining a delivery coordinate space (DCS); for each beam's eye view (BEV) plane of each vertex in the DCS, and for each ROI, evaluating a dose of the ROI using transport solutions; evaluating a BEV scores of each pixel of the BEV plane using the doses of the one or more ROIs; determining one or more BEV regions in the BEV plane based on the BEV scores; determining a BEV region connectivity manifold based on the BEV regions; determining a set of treatment trajectories based on the BEV region connectivity manifold; and determining one or more IMRT fields. Each treatment trajectory defines a path through a set of vertices in the DCS. Each IMRT field defines a direction of incidence corresponding to a vertex in the DCS.Type: GrantFiled: July 21, 2022Date of Patent: October 3, 2023Assignee: SIEMENS HEALTHINEERS INTERNATIONAL AGInventor: Santtu Ollila
-
Patent number: 11717701Abstract: A method of beam angle optimization for an IMRT radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs), defining a delivery coordinate space (DCS), for each ROI, solving an adjoint transport to obtain an adjoint solution field from the ROI, for each vertex in the DCS, evaluating an adjoint photon fluence by performing ray tracing of the adjoint solution field, evaluating a dose of the ROI using the adjoint photon fluence, for each vertex in the DCS, evaluating a respective beam's eye view (BEV) score of each pixel of a BEV plane using the doses of the one or more ROIs, determining one or more BEV regions in the BEV plane based on the BEV scores, determining a BEV region connectivity manifold based on the BEV regions, and determining a set of IMRT fields based on the BEV region connectivity manifold.Type: GrantFiled: September 27, 2019Date of Patent: August 8, 2023Assignees: SIEMENS HEALTHINEERS INTERNATIONAL AG, VARIAN MEDICAL SYSTEMS, INC.Inventors: Santtu Ollila, Todd Arlin Wareing, John Morton McGhee, Douglas Allen Barnett, Jr., Alexander Enrique Maslowski
-
Patent number: 11691028Abstract: Methods of beam angle optimization for intensity modulated radiotherapy (IMRT) treatment include determining beam's eye view (BEV) regions and a BEV region connectivity manifold by evaluating dose response of each region of interest for each vertex in a delivery coordinate space (DCS). The information contained in the BEV regions and the BEV region connectivity manifold is used to guide an optimizer to find optimal field geometries in the IMRT treatment. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.Type: GrantFiled: February 8, 2021Date of Patent: July 4, 2023Assignees: SIEMENS HEALTHINEERS INTERNATIONAL AG, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYInventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
-
Patent number: 11691027Abstract: Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.Type: GrantFiled: February 8, 2021Date of Patent: July 4, 2023Assignees: SIEMENS HEALTHINEERS INTERNATIONAL AG, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYInventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
-
Publication number: 20220370829Abstract: A method of determining treatment geometries for a radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs); defining a delivery coordinate space (DCS); for each beam's eye view (BEV) plane of each vertex in the DCS, and for each ROI, evaluating a dose of the ROI using transport solutions; evaluating a BEV scores of each pixel of the BEV plane using the doses of the one or more ROIs; determining one or more BEV regions in the BEV plane based on the BEV scores; determining a BEV region connectivity manifold based on the BEV regions; determining a set of treatment trajectories based on the BEV region connectivity manifold; and determining one or more IMRT fields. Each treatment trajectory defines a path through a set of vertices in the DCS. Each IMRT field defines a direction of incidence corresponding to a vertex in the DCS.Type: ApplicationFiled: July 21, 2022Publication date: November 24, 2022Inventor: Santtu Ollila
-
Publication number: 20220339468Abstract: A method of trajectory optimization for radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs), defining a delivery coordinate space (DCS), for each ROI, solving an adjoint transport to obtain an adjoint solution field from the ROI, for each vertex in the DCS, evaluating an adjoint photon fluence by performing ray tracing of the adjoint solution field, evaluating a dose of the ROI using the adjoint photon fluence, for each vertex in the DCS, evaluating a respective beam's eye view (BEV) score of each pixel of a BEV plane using the doses of the one or more ROIs, determining one or more BEV regions in the BEV plane based on the BEV scores, determining a BEV region connectivity manifold based on the BEV regions, and determining one or more optimal treatment trajectories based on the BEV region connectivity manifold.Type: ApplicationFiled: June 28, 2022Publication date: October 27, 2022Inventors: Santtu Ollila, Todd Arlin Wareing, John Morton McGhee, Douglas Allen Barnett, JR., Alexander Enrique Maslowski
-
Patent number: 11439842Abstract: A method of determining treatment geometries for a radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs); defining a delivery coordinate space (DCS); for each beam's eye view (BEV) plane of each vertex in the DCS, and for each ROI, evaluating a dose of the ROI using transport solutions; evaluating a BEV scores of each pixel of the BEV plane using the doses of the one or more ROIs; determining one or more BEV regions in the BEV plane based on the BEV scores; determining a BEV region connectivity manifold based on the BEV regions; determining a set of treatment trajectories based on the BEV region connectivity manifold; and determining one or more IMRT fields. Each treatment trajectory defines a path through a set of vertices in the DCS. Each IMRT field defines a direction of incidence corresponding to a vertex in the DCS.Type: GrantFiled: September 27, 2019Date of Patent: September 13, 2022Assignee: VARIAN MEDICAL SYSTEMS INTERNATIONAL AGInventor: Santtu Ollila
-
Patent number: 11400313Abstract: A method of trajectory optimization for radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs), defining a delivery coordinate space (DCS), for each ROI, solving an adjoint transport to obtain an adjoint solution field from the ROI, for each vertex in the DCS, evaluating an adjoint photon fluence by performing ray tracing of the adjoint solution field, evaluating a dose of the ROI using the adjoint photon fluence, for each vertex in the DCS, evaluating a respective beam's eye view (BEV) score of each pixel of a BEV plane using the doses of the one or more ROIs, determining one or more BEV regions in the BEV plane based on the BEV scores, determining a BEV region connectivity manifold based on the BEV regions, and determining one or more optimal treatment trajectories based on the BEV region connectivity manifold.Type: GrantFiled: September 27, 2019Date of Patent: August 2, 2022Assignees: VARIAN MEDICAL SYSTEMS, INC., VARIAN MEDICAL SYSTEMS INTERNATIONAL AGInventors: Santtu Ollila, Todd Arlin Wareing, John Morton McGhee, Douglas Allen Barnett, Jr., Alexander Enrique Maslowski
-
Publication number: 20220176160Abstract: In a radiation treatment plan that includes a plurality of treatment fields of multiple treatment modalities, such as IMRT modality and dynamic treatment path modality (e.g., VMAT and conformal arc therapy), an optimized spatial point sequence may be determined that optimizes the total treatment time, which includes both the beam-on time (i.e., during the delivery of radiation dose) and the beam-off time (i.e., during transitions between consecutive treatment fields). The result is a time-ordered field trajectory that intermixes and interleaves different treatment fields. In one embodiment, a dynamic treatment path may be cut into a plurality of sections, and one or more IMRT fields may be inserted between the plurality of sections.Type: ApplicationFiled: February 23, 2022Publication date: June 9, 2022Inventors: Santtu Ollila, Mikko Vainio, Jarkko Peltola, Janne Nord, Esa Kuusela, Juha Kauppinen, Viljo Petäjä, Marko Rusanen
-
Patent number: 11285339Abstract: In a radiation treatment plan that includes a plurality of treatment fields of multiple treatment modalities, such as IMRT modality and dynamic treatment path modality (e.g., VMAT and conformal arc therapy), an optimized spatial point sequence may be determined that optimizes the total treatment time, which includes both the beam-on time (i.e., during the delivery of radiation dose) and the beam-off time (i.e., during transitions between consecutive treatment fields). The result is a time-ordered field trajectory that intermixes and interleaves different treatment fields. In one embodiment, a dynamic treatment path may be cut into a plurality of sections, and one or more IMRT fields may be inserted between the plurality of sections.Type: GrantFiled: March 18, 2019Date of Patent: March 29, 2022Assignee: Varian Medical Systems International AGInventors: Santtu Ollila, Mikko Vainio, Jarkko Peltola, Janne Nord, Esa Kuusela, Juha Kauppinen, Viljo Petäjä, Marko Rusanen
-
Patent number: 11103726Abstract: Methods and systems are provided for developing radiation therapy treatment plans. A treatment template with radiation fields can be chosen for a patient based on a tumor location. Static radiation field positions can be adjusted for the patient, while arc radiation fields may remain the same. Static radiation field positions can be adjusted using dose gradient, historical patient data, and other techniques.Type: GrantFiled: March 31, 2020Date of Patent: August 31, 2021Assignee: Varian Medical Systems International AGInventors: Jarkko Peltola, Janne Nord, Santtu Ollila, Mikko Vainio, Esa Kuusela
-
Publication number: 20210178189Abstract: Methods of beam angle optimization for intensity modulated radiotherapy (IMRT) treatment include determining beam's eye view (BEV) regions and a BEV region connectivity manifold by evaluating dose response of each region of interest for each vertex in a delivery coordinate space (DCS). The information contained in the BEV regions and the BEV region connectivity manifold is used to guide an optimizer to find optimal field geometries in the IMRT treatment. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.Type: ApplicationFiled: February 8, 2021Publication date: June 17, 2021Applicants: Varian Medical Systems International AG, The Board of Trustees of the Leland Stanford Junior University, Office of the General CounselInventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
-
Publication number: 20210178188Abstract: Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.Type: ApplicationFiled: February 8, 2021Publication date: June 17, 2021Applicants: Varian Medical Systems International AG, The Board of Trustees of the Leland Stanford Junior University, Office of the General CounselInventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
-
Patent number: 10946217Abstract: Methods of beam angle optimization for intensity modulated radiotherapy (IMRT) treatment include determining beam's eye view (BEV) regions and a BEV region connectivity manifold by evaluating dose response of each region of interest for each vertex in a delivery coordinate space (DCS). The information contained in the BEV regions and the BEV region connectivity manifold is used to guide an optimizer to find optimal field geometries in the IMRT treatment. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.Type: GrantFiled: December 28, 2018Date of Patent: March 16, 2021Assignees: Varian Medical Systems International AG, The Board of Trustees of the Leland Stanford Junior University, Office of the General CounselInventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
-
Patent number: 10946216Abstract: Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.Type: GrantFiled: December 28, 2018Date of Patent: March 16, 2021Assignees: Varian Medical Systems International AG, The Board of Trustees of the Leland Stanford Junior University, Office of the General CounselInventors: Christopher Barry Locke, Santtu Ollila, Karl Kenneth Bush
-
Patent number: 10857384Abstract: Streamlined and partially automated methods of setting normal tissue objectives in radiation treatment planning are provided. These methods may be applied to multiple-target cases as well as single-target cases. The methods can impose one or more target-specific dose falloff constraints around each target, taking into account geometric characteristics of each target such as target volume and shape. In some embodiments, methods can also take into account a planner's preferences for target dose homogeneity. In some embodiments, methods can generate additional dose falloff constraints in locations between two targets where dose bridging is likely to occur.Type: GrantFiled: October 17, 2018Date of Patent: December 8, 2020Assignee: Varian Medical Systems International AGInventors: Santtu Ollila, Mikko Vainio, Jarkko Peltola, Janne Nord
-
Patent number: 10835760Abstract: A cost function is constructed so as to guide an optimization process to achieve similar coverage for all targets simultaneously in a concurrent radiation treatment of multiple targets, so that a single scaling factor may be used in a plan normalization to achieve the desired coverage for all the targets. The cost function includes a component that favors a solution that attains similar target coverages for all targets, as well as a component that favors a solution that approaches the desired target coverage value for each individual target. The cost function includes a max term relating to deficiencies of actual target coverages with respect to a desired target coverage, or alternatively a soft-max term relating to deviations of actual target coverages with respect to an average target coverage, as well as to deficiencies of actual target coverages with respect to a desired target coverage.Type: GrantFiled: November 13, 2019Date of Patent: November 17, 2020Assignee: Varian Medical Systems International AGInventors: Esa Kuusela, Emmi Ruokokoski, Santtu Ollila, Janne Nord, Jarkko Peltola
-
Publication number: 20200222720Abstract: Methods and systems are provided for developing radiation therapy treatment plans. A treatment template with radiation fields can be chosen for a patient based on a tumor location. Static radiation field positions can be adjusted for the patient, while arc radiation fields may remain the same. Static radiation field positions can be adjusted using dose gradient, historical patient data, and other techniques.Type: ApplicationFiled: March 31, 2020Publication date: July 16, 2020Applicant: Varian Medical Systems International AGInventors: Jarkko Peltola, Janne Nord, Santtu Ollila, Mikko Vainio, Esa Kuusela