Abstract: An engine system is provided, which includes a vehicle-mounted engine having an injector, a spark plug, an intake valve operating mechanism, and an exhaust valve operating mechanism, an accelerator opening sensor, and a controller. The engine is configured to execute flame propagation combustion and compressed self-ignition combustion. The controller performs a combustion control so that a target torque set based on an accelerator opening is realized in a specific cycle in the future from a present time by a given delay time. The controller sets beforehand the combustion mode based on a target load, estimates an in-cylinder property when the intake valve is closed in the present cycle, sets a target in-cylinder property so that the set combustion mode is realized in the specific cycle, and sets a target operating amount of each of the intake and exhaust valve operating mechanisms based on the set target in-cylinder property.

Abstract: An engine system is provided, which includes a vehicle-mounted engine having an injector, a spark plug, and a property adjusting device, an accelerator opening sensor, and a controller. The controller performs a combustion control for controlling the injector, the spark plug, and the property adjusting device so that a target torque set based on a present accelerator opening detected by the accelerator opening sensor is outputted in a specific cycle in the future from a present time by a given delay time. In the combustion control, the controller sets a target load of the engine in the specific cycle based on the present accelerator opening, and sets a combustion transition from the present cycle to the specific cycle by selecting beforehand combustion from the present cycle to the specific cycle, from flame propagation combustion and compressed self-ignition combustion, based on the set target load.

Abstract: A method of controlling an engine is provided, which includes setting, by a controller, a target torque of the engine in a specific cycle in the future by a given delay time from the present time based on a present accelerator opening. The method includes selecting beforehand, by the controller, combustion in the specific cycle according to the target torque, from flame propagation combustion and compressed self-ignition combustion. The method includes outputting, by the controller, a control signal to a property adjusting device before the specific cycle so that a property inside the cylinder in the specific cycle becomes a property corresponding to the selected combustion. The method includes estimating, by the controller, the property at a timing when an intake valve is closed in the specific cycle. The method includes outputting, by the controller, a control signal corresponding to the estimated property to a spark plug or an injector.

Abstract: A method of controlling an engine is provided, which includes setting, by a controller, a target torque of the engine in a specific cycle in the future by a given delay time from the present time based on a present accelerator opening. The method includes selecting beforehand, by the controller, combustion in the specific cycle according to the target torque, from flame propagation combustion and compressed self-ignition combustion. The method includes outputting, by the controller, a control signal to a property adjusting device before the specific cycle so that a property inside the cylinder in the specific cycle becomes a property corresponding to the selected combustion. The method includes estimating, by the controller, the property at a timing when an intake valve is closed in the specific cycle. The method includes outputting, by the controller, a control signal corresponding to the estimated property to a spark plug or an injector.

Abstract: An engine system is provided, which includes a vehicle-mounted engine having an injector, a spark plug, and a property adjusting device, an accelerator opening sensor, and a controller. The controller performs a combustion control for controlling the injector, the spark plug, and the property adjusting device so that a target torque set based on a present accelerator opening detected by the accelerator opening sensor is outputted in a specific cycle in the future from a present time by a given delay time. In the combustion control, the controller sets a target load of the engine in the specific cycle based on the present accelerator opening, and sets a combustion transition from the present cycle to the specific cycle by selecting beforehand combustion from the present cycle to the specific cycle, from flame propagation combustion and compressed self-ignition combustion, based on the set target load.

Abstract: An engine system is provided, which includes a vehicle-mounted engine having an injector, a spark plug, an intake valve operating mechanism, and an exhaust valve operating mechanism, an accelerator opening sensor, and a controller. The engine is configured to execute flame propagation combustion and compressed self-ignition combustion. The controller performs a combustion control so that a target torque set based on an accelerator opening is realized in a specific cycle in the future from a present time by a given delay time. The controller sets beforehand the combustion mode based on a target load, estimates an in-cylinder property when the intake valve is closed in the present cycle, sets a target in-cylinder property so that the set combustion mode is realized in the specific cycle, and sets a target operating amount of each of the intake and exhaust valve operating mechanisms based on the set target in-cylinder property.

Abstract: An engine system is provided, which includes a vehicle-mounted engine having an injector, a spark plug, an intake valve operating mechanism, and an exhaust valve operating mechanism, an accelerator opening sensor, and a controller. The controller sets beforehand a combustion mode so that a target torque set based on an accelerator opening is realized in a specific cycle in the future from a present time by a given delay time, sets an in-cylinder property when an intake valve is closed in the specific cycle so that the set combustion mode is realized in the specific cycle, estimates the actual in-cylinder property when the intake valve is closed in the specific cycle, when the delay time passes and the cycle becomes the specific cycle, and adjusts an operating amount of at least one of the injector and the spark plug, when the estimated in-cylinder property deviates from the target in-cylinder property.

Abstract: A fusion protein including a Cas9 protein and a modifying peptide that modifies the Cas9 protein, in which the modifying peptide includes: a peptide composed of the amino acid sequence described in SEQ ID NO: 29; or a peptide composed of an amino acid sequence in which one or several amino acids are deleted, substituted, or added in the amino acid sequence described in SEQ ID NO: 29 and having activity to localize the Cas9 protein in the nucleus by forming a fusion protein with the Cas9 protein.

Abstract: A spark-ignition direct injection engine is provided. The engine includes an engine body, a fuel injection valve, a fuel pressure setting mechanism, an ignition plug, and a controller. The controller switches between a compression-ignition mode where the engine body is operated to perform compression-ignition combustion and a spark-ignition mode where the engine body is operated to perform spark-ignition combustion. Immediately after switching from the spark-ignition mode to the compression-ignition mode, the controller operates the engine body in a compression-ignition initial mode where the fuel pressure is set to be 30 MPa or above and the fuel injection valve is controlled to perform the fuel injection in a period from a late stage of the compression stroke to an early stage of the expansion stroke so that the gas mixture self-ignites to combust.

Abstract: A spark-ignition direct injection engine is provided. The engine includes an engine body, a fuel injection valve, a fuel pressure setting mechanism, an ignition plug, and a controller. The controller switches between a compression-ignition mode where the engine body is operated to perform compression-ignition combustion and a spark-ignition mode where the engine body is operated to perform spark-ignition combustion. Immediately after switching from the spark-ignition mode to the compression-ignition mode, the controller operates the engine body in a compression-ignition initial mode where the fuel pressure is set to be 30 MPa or above and the fuel injection valve is controlled to perform the fuel injection in a period from a late stage of the compression stroke to an early stage of the expansion stroke so that the gas mixture self-ignites to combust.