Patents by Inventor Sara Birtalan

Sara Birtalan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BINDING POLYPEPTIDES WITH RESTRICTED DIVERSITY SEQUENCES
    Publication number: 20070237764
    Abstract: The invention provides variant CDRs comprising highly restricted amino acid sequence diversity. These polypeptides provide a flexible and simple source of sequence diversity that can be used as a source for identifying novel antigen binding polypeptides. The invention also provides these polypeptides as fusion polypeptides to heterologous polypeptides such as at least a portion of phage or viral coat proteins, tags and linkers. Libraries comprising a plurality of these polypeptides are also provided. In addition, methods of and compositions for generating and using these polypeptides and libraries are provided.
    Type: Application
    Filed: December 1, 2006
    Publication date: October 11, 2007
    Applicant: Genentech, Inc.
    Inventors: Sara Birtalan, Frederic Fellouse, Sachdev Sidhu
  • Binding Polypeptides and Uses Thereof
    Publication number: 20070202552
    Abstract: The invention provides antibodies or antigen binding fragments thereof to DR5 and HER-2. The antibodies and/or antigen binding fragments thereof comprise variant CDRs comprising highly restricted amino acid sequence diversity. The invention also provides these polypeptides as fusion polypeptides to heterologous polypeptides such as at least a portion of phage or viral coat proteins, tags and linkers. In addition, compositions and methods of use for treatment of cancer and immune related conditions are provided.
    Type: Application
    Filed: December 1, 2006
    Publication date: August 30, 2007
    Applicant: Genentech, Inc.
    Inventors: Sachdev Sidhu, Sara Birtalan, Frederic Fellouse