Patents by Inventor Sara Garwick

Sara Garwick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant virus products and methods for inhibition of expression of DUX4
    Patent number: 9469851
    Abstract: The present invention relates to RNA interference-based methods for inhibiting the expression of the DUX4 gene, a double homeobox gene on human chromosome 4q35. Recombinant adeno-associated viruses of the invention deliver DNAs encoding microRNAs that knock down the expression of DUX4. The methods have application in the treatment of muscular dystrophies such as facioscapulohumeral muscular dystrophy.
    Type: Grant
    Filed: July 24, 2012
    Date of Patent: October 18, 2016
    Assignee: NATIONWIDE CHILDREN'S HOSPITAL, INC.
    Inventors: Scott Quenton Harper, Jian Liu, Sara Garwick Coppens, Lindsay Wallace
  • Recombinant Virus Products and Methods for Inhibition of Expression of DUX4
    Publication number: 20140322169
    Abstract: The present invention relates to RNA interference-based methods for inhibiting the expression of the DUX4 gene, a double homeobox gene on human chromosome 4q35. Recombinant adeno-associated viruses of the invention deliver DNAs encoding microRNAs that knock down the expression of DUX4. The methods have application in the treatment of muscular dystrophies such as facioscapulohumeral muscular dystrophy.
    Type: Application
    Filed: July 24, 2012
    Publication date: October 30, 2014
    Applicant: NATIONWIDE CHILDREN'S HOSPITAL, INC.
    Inventors: Scott Quenton Harper, Jian Liu, Sara Garwick, Lindsay Wallace