Patents by Inventor Sara Holmqvist

Sara Holmqvist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted azetidine compounds of formula (I) useful in the treatment of functional gastrointestinal disorders, IBS, and functional dyspepsia
    Patent number: 8288370
    Abstract: The present invention relates to new substituted azetidine compounds of formula (I): or pharmaceutically acceptable salts thereof, as further described herein, to pharmaceutical compositions containing them, and the use of the compounds in the treatment of functional gastrointestinal disorders, IBS, and functional dyspepsia. The compounds are neurokinin (NK) antagonists. The present invention further relates to processes for the preparation of the compounds.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: October 16, 2012
    Assignee: Albireo AB
    Inventors: Rolf Bergman, Sara Holmqvist, Sverker Von Unge
  • Novel Azetidine Compounds Useful in the Treatment of Functional Gastrointestinal Disorders, Ibs and Functional Dyspepsia
    Publication number: 20100311713
    Abstract: The present invention relates to new azetidine compounds, to pharmaceutical compositions containing them and the use of said compounds in the treatment of functional gastrointestinal disorders, IBS and functional dyspepsia. The compounds are neurokinin (NK) antagonists. The present invention further relates to processes for the preparation of the compounds.
    Type: Application
    Filed: September 27, 2006
    Publication date: December 9, 2010
    Inventors: Rolf Bergman, Sara Holmqvist, Sverker Von Unge
  • New Azetidine Derivatives as Neurokinin Receptor Antagonists for the Treatment of Gastrointestinal Diseases
    Publication number: 20100069346
    Abstract: The application relates to new piperazine- or morpholine-substituted azetidine derivatives of formula I. These compounds are antagonists at the neurokinin receptor and can be used for the treatment of gastrointestinal diseases. The application also relates to processes for the preparation of the compounds and to intermediates in said preparation.
    Type: Application
    Filed: June 21, 2006
    Publication date: March 18, 2010
    Inventors: Sara Holmqvist, Anders Chansson, Ame Svensson, Sverker Von Unge
  • Novel Compounds 737
    Publication number: 20090023704
    Abstract: The present invention relates to novel xanthine compounds of the general formula (I) wherein R1, R2, R3 and R4 are as defined, having a positive allosteric GABAB receptor (GBR) modulator effect, methods for the preparation of said compounds and to their use, optionally in combination with a GABAB agonist, for the inhibition of transient lower esophageal sphincter relaxations, for the treatment of gastroesophageal reflux disease, as well as for the treatment of functional gastrointestinal disorders and irritable bowel syndrome (IBS).
    Type: Application
    Filed: April 17, 2008
    Publication date: January 22, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Leifeng Cheng, Sara Holmqvist, Florian Raubacher, Peter Schell