Patents by Inventor Sara Le

Sara Le has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods generating conversational responses using machine learning models
    Patent number: 11973725
    Abstract: Methods and systems are described for generating dynamic conversational responses using two-tier machine learning models. The dynamic conversational responses may be generated in real time and reflect the likely goals and/or intents of a user. The two-tier machine learning model may include a first tier that determines an intent cluster based on a feature input, and a second tier that determines a specific intent from the cluster.
    Type: Grant
    Filed: August 30, 2022
    Date of Patent: April 30, 2024
    Assignee: Capital One Services, LLC
    Inventors: Minh Le, Sara Mikulic
  • Highly Sensitive Biomarker Panels
    Publication number: 20160091497
    Abstract: Cardiovascular disease, e.g., congestive heart failure, is often first diagnosed after the onset of clinical symptoms, eliminating potential for early intervention. The invention provides a multi-marker immunoassay, including cardiac pathology and vascular inflammation biomarkers, yielding a more sensitive assay for early detection of CHF in plasma. A panel consisting of cardiac pathology (cTnI, BNP) and vascular inflammation (IL-6, TNF?, IL-17a) biomarkers provided a sensitivity of 94% for association with CHF.
    Type: Application
    Filed: June 29, 2015
    Publication date: March 31, 2016
    Inventors: Philippe J. Goix, Robert Puskas, John Todd, Richard Livingston, Douglas Held, Sara Le
  • Highly sensitive biomarker panels
    Patent number: 9068991
    Abstract: Cardiovascular disease, e.g., congestive heart failure, is often first diagnosed after the onset of clinical symptoms, eliminating potential for early intervention. The invention provides a multi-marker immunoassay, including cardiac pathology and vascular inflammation biomarkers, yielding a more sensitive assay for early detection of CHF in plasma. A panel consisting of cardiac pathology (cTnI, BNP) and vascular inflammation (IL-6, TNF?, IL-17a) biomarkers provided a sensitivity of 94% for association with CHF.
    Type: Grant
    Filed: March 9, 2013
    Date of Patent: June 30, 2015
    Assignee: Singulex, Inc.
    Inventors: Philippe J. Goix, Robert Puskas, John Todd, Richard Livingston, Douglas Held, Sara Le
  • Highly Sensitive Biomarker Panels
    Publication number: 20130261009
    Abstract: Cardiovascular disease, e.g., congestive heart failure, is often first diagnosed after the onset of clinical symptoms, eliminating potential for early intervention. The invention provides a multi-marker immunoassay, including cardiac pathology and vascular inflammation biomarkers, yielding a more sensitive assay for early detection of CHF in plasma. A panel consisting of cardiac pathology (cTnI, BNP) and vascular inflammation (IL-6, TNF?, IL-17a) biomarkers provided a sensitivity of 94% for association with CHF.
    Type: Application
    Filed: March 9, 2013
    Publication date: October 3, 2013
    Applicant: SINGULEX, INC.
    Inventors: Philippe J. Goix, Robert Puskas, John Todd, Richard Livingston, Douglas Held, Sara Le
  • Highly sensitive biomarker panels
    Patent number: 8450069
    Abstract: Cardiovascular disease, e.g., congestive heart failure, is often first diagnosed after the onset of clinical symptoms, eliminating potential for early intervention. The invention provides a multi-marker immunoassay, including cardiac pathology and vascular inflammation biomarkers, yielding a more sensitive assay for early detection of CHF in plasma. A panel consisting of cardiac pathology (cTnI, BNP) and vascular inflammation (IL-6, TNF?, IL-17a) biomarkers provided a sensitivity of 94% for association with CHF.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: May 28, 2013
    Assignee: Singulex, Inc.
    Inventors: Philippe J. Goix, Robert Puskas, John Todd, Richard Livingston, Douglas Held, Sara Le
  • Highly Sensitive Biomarker Panels
    Publication number: 20110003707
    Abstract: Cardiovascular disease, e.g., congestive heart failure, is often first diagnosed after the onset of clinical symptoms, eliminating potential for early intervention. The invention provides a multi-marker immunoassay, including cardiac pathology and vascular inflammation biomarkers, yielding a more sensitive assay for early detection of CHF in plasma. A panel consisting of cardiac pathology (cTnI, BNP) and vascular inflammation (IL-6, TNF?, IL-17a) biomarkers provided a sensitivity of 94% for association with CHF.
    Type: Application
    Filed: June 7, 2010
    Publication date: January 6, 2011
    Inventors: Philippe J. Goix, Robert Puskas, John Todd, Richard Livingston, Douglas Held, Sara Le