Patents by Inventor Sara MAJOCCHI

Sara MAJOCCHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240254234
    Abstract: The present invention relates to PD-L1xCD28 bispecific antibodies which act as immune checkpoint inhibitors by binding to and blocking PD-L1 (thus preventing its engagement with PD-1 expressed on T cells) that can further deliver a costimulatory signal to T cells by clustering and agonistically engaging CD28.
    Type: Application
    Filed: October 20, 2023
    Publication date: August 1, 2024
    Inventors: Sara MAJOCCHI, Valéry MOINE, Krzysztof M. MASTERNAK, Limin SHANG, Walter FERLIN
  • Publication number: 20240084001
    Abstract: The invention provides bispecific antibodies binding to human carcinoembryonic antigen CEACAM5 and human CD47, polynucleotides encoding such bispecific antibodies and vectors and host cells comprising such polynucleotides. The invention further provides methods for selecting and producing such antibodies and methods of using such antibodies in the treatment of diseases in monotherapy as well in combination.
    Type: Application
    Filed: December 8, 2022
    Publication date: March 14, 2024
    Applicant: LamKap Bio beta Ltd.
    Inventors: Vanessa BUATOIS, Sara MAJOCCHI, Klaus STREIN
  • Publication number: 20240002544
    Abstract: The present invention relates to antibody arms which bind agonistically to human CD28. The present invention relates to bispecific antibodies which bind to human carcinoembryonic antigen (CEA) and human CD28 using the agonist anti-CD28 arms described herein. The present invention relates to bispecific antibodies which bind to human mesothelin (MSLN) and human CD28 using the agonist anti-CD28 arms described herein.
    Type: Application
    Filed: March 7, 2023
    Publication date: January 4, 2024
    Inventors: Sara MAJOCCHI, Krzysztof MASTERNAK, Limin SHANG, Nicolas FISCHER, Xavier CHAUCHET
  • Publication number: 20230136228
    Abstract: The present invention relates to bispecific antibodies which bind to human carcinoembryonic antigen CEACAM5 (CEA) and human CD3?. In addition, the present invention relates to polynucleotides encoding such bispecific antibodies and vectors and host cells comprising such polynucleotides. The invention further relates to methods for selecting and producing such antibodies and to methods of using such antibodies in the treatment of diseases.
    Type: Application
    Filed: September 17, 2020
    Publication date: May 4, 2023
    Inventors: Klaus STREIN, Sara MAJOCCHI
  • Publication number: 20210221908
    Abstract: The invention provides bispecific antibodies binding to human carcinoembryonic antigen CEACAM5 and human CD47, polynucleotides encoding such bispecific antibodies and vectors and host cells comprising such polynucleotides. The invention further provides methods for selecting and producing such antibodies and methods of using such antibodies in the treatment of diseases inmonotherapy as well in combination.
    Type: Application
    Filed: May 31, 2019
    Publication date: July 22, 2021
    Inventors: Vanessa BUATOIS, Sara MAJOCCHI, Klaus STREIN