Abstract: The invention provides a process to reduce the particle size of ivermectin wherein the process comprises incorporating ivermectin particles in a wet or liquid medium and subjecting the medium comprising the particles to mixing in a high shear mixer.

Abstract: An amorphous form of a chelating agent is provided, in particular wherein the chelating agent comprises ethylenediaminetetraacetic acid/edetic acid (EDTA), diethylenetriaminepentaacetic acid/pentetic acid (DTPA), nitrilotriacetic acid (NTA), amino tris(methylenephosphonic acid) (ATMP), ethylenediamine tetramethylene phosphonic acid (EDTMP), 1-hydroxyethane 1,1-diphosphonic acid (HEDP), ethylenediaminedisuccinic acid (EDDS), iminodisuccinic acid (IDS), hydroxamic acid, oxalic acid, galactaric acid, metaphosphoric acid, or phytic acid, or a salt of any one or more of the above acids, or a mixture of two or more of any of the above acids or salts thereof. A process for preparing an amorphous form of a chelating agent comprises the steps of: a) Dissolving the chelating agent in a suitable solvent; b) Optionally purifying the solution; c) Isolating an amorphous form of the chelating agent; d) Optionally post drying or conditioning the amorphous form of the chelating agent.