Patents by Inventor Sarah A. Fingar

Sarah A. Fingar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the determination of a specific binding ligand using a vanadium bromoperoxidase as a signal-generating enzyme
    Patent number: 6322992
    Abstract: An analytical element can be used to sensitively and rapidly detect a wide variety of specific binding ligands in either a competitive or sandwich assay format. The assays are carried out using a vanadium bromoperoxidase-labeled immunoreactant and a chemiluminescent signal-providing wash composition which comprises a 2,3-dihydro-1,4-phthalazinedione derivative; a halogen, pseudohalogen, halogen-providing source or pseudohalogen-providing source; and a peroxide or a peroxide-generating reagent composition.
    Type: Grant
    Filed: October 17, 1997
    Date of Patent: November 27, 2001
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Alan Eric Friedman, Thomas Robert Kissel, Sarah Fingar Groulx, Martha Miller Kopcienski
  • Use of vanadium bromoperoxidase as a signal-generating enzyme for chemiluminescent systems: test kits and analytical methods
    Patent number: 5811253
    Abstract: Aqueous compositions, test kits and methods can be used to detect hydrogen peroxide or vanadium bromoperoxidase by generating a chemiluminescent signal in the presence of the analyte. Signal generation as well as reaction kinetics are improved by using a composition which comprises a 2,3-dihydro-1,4-phthalazinedione derivative; a halogen, pseudohalogen, halogen-providing or pseudohalogen-providing source; and a peroxide or peroxide-generating reagent composition.
    Type: Grant
    Filed: September 1, 1995
    Date of Patent: September 22, 1998
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Alan Eric Friedman, Sarah Fingar Groulx, Alison Butler
  • Chemiluminescent reagent and assay using a substituted acetanilide for light generation
    Patent number: 5705357
    Abstract: A simplified composition for generating a chemiluminescent signal in the presence of a peroxidase includes a substituted acetanilide as the sole light-producing substrate for the peroxidase. Assays for various analytes can be carried out with this composition at near neutral pH, exhibit low background and are highly sensitive.
    Type: Grant
    Filed: August 29, 1994
    Date of Patent: January 6, 1998
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Thomas Robert Kissel, Alan E. Friedman, Sarah A. Fingar