Patents by Inventor Sarah BAILEY

Sarah BAILEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLUBLE TCRS AND FUSIONS TO ANTI-CD3 RECOGNIZING KRAS G12D FOR THE TREATMENT OF CANCER
    Publication number: 20230348595
    Abstract: The present invention relates to specific binding molecules which bind to an HLA-restricted peptide derived from mutant KRAS. Said specific binding molecules may comprise CDR sequences embedded within a framework sequence. The CDRs and framework sequences may correspond to a T cell receptor (TCR) variable domain and may further comprise non-natural mutations relative to a native TCR variable domain. The specific binding molecules of the invention are particularly suitable for use as novel immunotherapeutic reagents for the treatment of cancer.
    Type: Application
    Filed: May 4, 2021
    Publication date: November 2, 2023
    Inventors: Chandramouli CHILLAKURI, Andrew POOLE, Sarah BAILEY