Abstract: A 3D printed assisted technology for the visually impaired may contain two separate, identical, low-cost, 3D printed models of cross-sectioned neuroanatomical structures. Both of these models may contain identical tactile, topographical sections that emphasize different systems of the brain. One model may contain pressable buttons and programmable audio components that present audio information to the future and correspond to features on the 3D model.

Abstract: The invention relates to heterocyclic substituted urea derivatives that display selective binding to dopamine D3 receptors. In another aspect, the invention relates to a method for treating central nervous system disorders associated with the dopamine D3 receptor activity in a patient in need of such treatment comprising administering to the subject a therapeutically effective amount of said compounds for alleviation of such disorder. The central nervous system disorders that may be treated with these compounds include Psychotic Disorders, Substance Dependence, Substance Abuse, Dyskinetic Disorders (e.g. Parkinson's Disease, Parkinsonism, Neuroleptic-Induced Tardive Dyskinesia, Gilles de la Tourette Syndrome and Huntington's Disease), Dementia, Anxiety Disorders, Sleep Disorders, Circadian Rhythm Disorders and Mood Disorders.