Patents by Inventor Sarah Calve

Sarah Calve has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8097455
    Abstract: A system and method for forming a skeletal muscle construct include primary muscle cells provided on a substrate without disposing the cells within an exogenous scaffold, the cells cultured in vitro such that the cells form a confluent monolayer; at least two anchors secured to the monolayer in spaced relationship; and at least one secondary tissue, such as neural or tendon tissue, provided in contact with the monolayer such that the monolayer detaches from the substrate and self-organizes to at least partially surround the at least one secondary tissue, thereby forming a three-dimensional skeletal muscle construct having a functional interface with the secondary tissue.
    Type: Grant
    Filed: February 4, 2008
    Date of Patent: January 17, 2012
    Assignee: The Regents of the University of Michigan
    Inventors: Lisa M. Larkin, Ellen M. Arruda, Sarah Calve, Tatiana Y. Kostriminova
  • Publication number: 20080193910
    Abstract: A system and method for forming a skeletal muscle construct include primary muscle cells provided on a substrate without disposing the cells within an exogenous scaffold, the cells cultured in vitro such that the cells form a confluent monolayer; at least two anchors secured to the monolayer in spaced relationship; and at least one secondary tissue, such as neural or tendon tissue, provided in contact with the monolayer such that the monolayer detaches from the substrate and self-organizes to at least partially surround the at least one secondary tissue, thereby forming a three-dimensional skeletal muscle construct having a functional interface with the secondary tissue.
    Type: Application
    Filed: February 4, 2008
    Publication date: August 14, 2008
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Lisa M. Larkin, Ellen M. Arruda, Sarah Calve, Tatiana Y. Kostriminova