Patents by Inventor Sarah D. Clayton

Sarah D. Clayton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4387228
    Abstract: A process for the production of (.+-.)3-deazaaristeromycin, which is also known as (.+-.)-4-amino-1-[(1.alpha., 2.beta., 3.beta., 4.alpha.)-2,3-dihydroxy-4-(hydroxymethyl)-cyclopentyl]imidazo[4,5-c]pyridi ne, which comprises:(1) reacting 2,4-dichloro-3-nitropyridine with (.+-.)(1,4/2,3)-4-amino-2,3-dihydroxy-1-cyclopentanemethanol to give (.+-.)-(1,4/2,3)-4-(3-nitro-2-chloro-4-pyridylamino)-2,3-dihydroxy-1-cyclo pentanemethanol (compound II);(2) subsequently reducing compound II to (.+-.)-(1,4/2,3)-4(3-amino-2-chloro-4-pyridylamino)-2,3-dihydroxy-1-cyclop entanemethanol (compound III);(3) acid catalyzed cyclization of compound III to (.+-.)-4-chloro-1-(1.alpha., 2.beta., 3.beta., 4.alpha.)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)imidazo[4,5-c]pyridin e (compound IV);(4) displacing the chloro group of compound IV to produce (.+-.)-4-hydrazino-1-(1.alpha., 2.beta., 3.beta., 4.alpha.
    Type: Grant
    Filed: September 16, 1981
    Date of Patent: June 7, 1983
    Assignee: Southern Research Institute
    Inventors: John A. Montgomery, Sarah D. Clayton