Patents by Inventor Sarah E. Bondos

Sarah E. Bondos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240116992
    Abstract: Provided herein are compositions and methods for stabilizing enzymes. Also provided are systems, compositions and methods for using the stabilized enzymes to produce a desired compound.
    Type: Application
    Filed: February 2, 2022
    Publication date: April 11, 2024
    Applicant: Bondwell Technologies LP
    Inventors: David W. Howell, Sarah E. Bondos, Rebecca M. Booth, Christi Parham, Dat P. Truong, Rebecca E. Skouby
  • Publication number: 20240083957
    Abstract: The present disclosure relates, in some embodiments, to a composition comprising a biomaterial. A biomaterial may comprise, for example, one or more molecules capable of self-association and/or self-assembly. In some embodiments, a biomaterial may comprise one or more polypeptides and/or proteins. A biomaterial may comprise, for example, two or more self-assembled Ultrabithorax (Ubx) protein molecules. A Ubx protein, in some embodiments, may be any wild type Drosophila melanogaster Ultrabithorax protein, including any natural or non-natural isoforms (e.g., alternative splicing isoforms). The present disclosure relates, in some embodiments, to a method of making a biomaterial comprising contacting two or more Ubx protein molecules under conditions that permit self-assembly to form a first fibril and contacting the first fibril to a second fibril.
    Type: Application
    Filed: March 13, 2023
    Publication date: March 14, 2024
    Inventors: Sarah E. BONDOS, Alexandra M. WHITELEY, Kathleen S. MATTHEWS, Zhao HUANG, Autumn BRAWLEY, Jan PATTERSON
  • Patent number: 11603393
    Abstract: The present disclosure relates, in some embodiments, to a composition comprising a biomaterial. A biomaterial may comprise, for example, one or more molecules capable of self-association and/or self-assembly. In some embodiments, a biomaterial may comprise one or more polypeptides and/or proteins. A biomaterial may comprise, for example, two or more self-assembled Ultrabithorax (Ubx) protein molecules. A Ubx protein, in some embodiments, may be any wild type Drosophila melanogaster Ultrabithorax protein, including any natural or non-natural isoforms (e.g., alternative splicing isoforms). The present disclosure relates, in some embodiments, to a method of making a biomaterial comprising contacting two or more Ubx protein molecules under conditions that permit self-assembly to form a first fibril and contacting the first fibril to a second fibril.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: March 14, 2023
    Assignee: BONDWELL TECHNOLOGIES LP
    Inventors: Sarah E. Bondos, Alexandra M. Whiteley, Kathleen S. Matthews, Zhao Huang, Autumn Brawley, Jan Patterson
  • Publication number: 20220251147
    Abstract: Provided herein are methods and compositions for purifying antibodies. Purification is achieved by increasing the binding capacity of protein A chromatography by covalent attachment of a protein A domain (E, D, A, B, C), or domain Z, or a functional variant thereof, to Drosophila melanogaster transcription factor Ultrabithorax (Ubx) materials. The compositions include fusion proteins containing Drosophila melanogaster transcription factor Ultrabithorax (Ubx) or a fragment thereof and an immunoglobulin binding protein. In some embodiments, the immunoglobulin binding protein is a protein A domain, a protein Z domain or a fragment thereof.
    Type: Application
    Filed: April 2, 2020
    Publication date: August 11, 2022
    Inventors: Sarah E. BONDOS, David W. HOWELL
  • Publication number: 20220033451
    Abstract: The present disclosure relates, in some embodiments, to a composition comprising a biomaterial. A biomaterial may comprise, for example, one or more molecules capable of self-association and/or self-assembly. In some embodiments, a biomaterial may comprise one or more polypeptides and/or proteins. A biomaterial may comprise, for example, two or more self-assembled Ultrabithorax (Ubx) protein molecules. A Ubx protein, in some embodiments, may be any wild type Drosophila melanogaster Ultrabithorax protein, including any natural or non-natural isoforms (e.g., alternative splicing isoforms). The present disclosure relates, in some embodiments, to a method of making a biomaterial comprising contacting two or more Ubx protein molecules under conditions that permit self-assembly to form a first fibril and contacting the first fibril to a second fibril.
    Type: Application
    Filed: June 9, 2021
    Publication date: February 3, 2022
    Inventors: Sarah E. Bondos, Alexandra M. Whiteley, Kathleen S. Matthews, Zhao Huang, Autumn Brawley, Jan Patterson
  • Patent number: 11059872
    Abstract: The present disclosure relates, in some embodiments, to a composition comprising a biomaterial. A biomaterial may comprise, for example, one or more molecules capable of self-association and/or self-assembly. In some embodiments, a biomaterial may comprise one or more polypeptides and/or proteins. A biomaterial may comprise, for example, two or more self-assembled Ultrabithorax (Ubx) protein molecules. A Ubx protein, in some embodiments, may be any wild type Drosophila melanogaster Ultrabithorax protein, including any natural or non-natural isoforms (e.g., alternative splicing isoforms). The present disclosure relates, in some embodiments, to a method of making a biomaterial comprising contacting two or more Ubx protein molecules under conditions that permit self-assembly to form a first fibril and contacting the first fibril to a second fibril.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: July 13, 2021
    Assignee: BONDWELL TECHNOLOGIES LP
    Inventors: Sarah E. Bondos, Alexandra M. Greer, Kathleen S. Matthews, Zhao Huang, Autumn Brawley, Jan Patterson
  • Publication number: 20100143436
    Abstract: The present disclosure relates, in some embodiments, to a composition comprising a biomaterial. A biomaterial may comprise, for example, one or more molecules capable of self-association and/or self-assembly. In some embodiments, a biomaterial may comprise one or more polypeptides and/or proteins. A biomaterial may comprise, for example, two or more self-assembled Ultrabithorax (Ubx) protein molecules. A Ubx protein, in some embodiments, may be any wild type Drosophila melanogaster Ultrabithorax protein, including any natural or non-natural isoforms (e.g., alternative splicing isoforms). The present disclosure relates, in some embodiments, to a method of making a biomaterial comprising contacting two or more Ubx protein molecules under conditions that permit self-assembly to form a first fibril and contacting the first fibril to a second fibril.
    Type: Application
    Filed: November 13, 2009
    Publication date: June 10, 2010
    Inventors: Sarah E. Bondos, Alexandra M. Greer, Kathleen S. Matthews, Zhao Huang, Autumn Brawley, Jan Patterson