Patents by Inventor Sarah E. DE LEO

Sarah E. DE LEO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods, compositions, and systems for activation and expansion of cells
    Patent number: 10301590
    Abstract: The disclosure provides for compositions, systems, and methods of cell expansion, stimulation and/or differentiation. The disclosure further provides for a mesh substrate and associated methods capable of stimulating cell expansion, for example, T cell or stem cell expansion. In another aspect, the disclosure provides for an electrospun mesh substrate and methods of using thereof comprising a silicone rubber composition, for example, polydimethylsiloxane, PLC, or combinations thereof.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: May 28, 2019
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Lance C. Kam, Helen H. Lu, Sarah E. De Leo, Keenan T. Bashour, Danielle Bogdanowicz, Philip Chuang
  • Methods, Compositions, and Systems for Activation and Expansion of Cells
    Publication number: 20170029767
    Abstract: The disclosure provides for compositions, systems, and methods of cell expansion, stimulation and/or differentiation. The disclosure further provides for a mesh substrate and associated methods capable of stimulating cell expansion, for example, T cell or stem cell expansion. In another aspect, the disclosure provides for an electrospun mesh substrate and methods of using thereof comprising a silicone rubber composition, for example, polydimethylsiloxane, PLC, or combinations thereof.
    Type: Application
    Filed: April 10, 2015
    Publication date: February 2, 2017
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Lance C. KAM, Helen H. LU, Sarah E. DE LEO, Keenan T. BASHOUR, Danielle BOGDANOWICZ, Philip CHUANG