Patents by Inventor Sarah E. KLEINSTEIN

Sarah E. KLEINSTEIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230407299
    Abstract: Disclosed herein are compositions comprising an oligonucleotide that targets SOS Ras/Rho guanine nucleotide exchange factor 2 (SOS2). The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating conditions associated with SOS2 mutations that include providing an oligonucleotide that targets SOS2 to a subject.
    Type: Application
    Filed: November 22, 2021
    Publication date: December 21, 2023
    Inventors: Omri GOTTESMAN, Shannon BRUSE, Brian CAJES, David JAKUBOSKY, Sarah E. KLEINSTEIN, John VEKICH