Patents by Inventor Sarah E. Tully

Sarah E. Tully has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies to sulfated carbohydrates
    Patent number: 8912011
    Abstract: The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to chondroitin sulfate, particularly CS-A, CS-C and CS-E tetrasaccharides. The present invention also relates to methods of making anti-CS antibodies, pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for diagnosis and treatment.
    Type: Grant
    Filed: July 29, 2009
    Date of Patent: December 16, 2014
    Assignee: California Institute of Technology
    Inventors: Sarah E. Tully, Linda C. Hsieh-Wilson
  • Chondroitin sulfate binding proteins and modulators thereof
    Patent number: 8623610
    Abstract: Chondroitin sulfate polysaccharides with defined sulfation patterns can be synthesized. These chondroitin polysaccharides can be used to identify chondroitin sulfate binding proteins. Further, compounds that modulate the activity of chondroitin sulfate binding proteins can be identified. For example, TNF-? was found to bind specifically to CS-E and CS-E can be used to modulate the interaction of TNF-? with the TNF receptor.
    Type: Grant
    Filed: May 22, 2007
    Date of Patent: January 7, 2014
    Assignee: California Institute of Technology
    Inventors: Cristal I. Gama, Sarah E. Tully, Linda C. Hsieh-Wilson
  • Small molecule stimulators of neuronal growth
    Patent number: 8338387
    Abstract: Provided herein are small molecule stimulators of neuronal growth, their preparation, and their use for treatment of neurological disorders. In one embodiment, provided herein are methods of treatment, prevention, or amelioration of a variety of medical conditions associated with neurological disorders using the compounds and compositions provided herein.
    Type: Grant
    Filed: July 29, 2009
    Date of Patent: December 25, 2012
    Assignee: California Institute of Technology
    Inventors: Linda C. Hsieh-Wilson, Sarah E. Tully, Ross Mabon, Cristal I. Gama
  • Antibodies to sulfated carbohydrates
    Patent number: 7745584
    Abstract: The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to chondroitin sulfate, particularly CS-A, CS-C and CS-E tetrasaccharides. The present invention also relates to methods of making anti-CS antibodies, pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for diagnosis and treatment.
    Type: Grant
    Filed: May 22, 2007
    Date of Patent: June 29, 2010
    Assignee: California Institute of Technology
    Inventors: Sarah E. Tully, Linda Hsieh-Wilson
  • SMALL MOLECULE STIMULATORS OF NEURONAL GROWTH
    Publication number: 20100075920
    Abstract: Provided herein are small molecule stimulators of neuronal growth, their preparation, and their use for treatment of neurological disorders. In one embodiment, provided herein are methods of treatment, prevention, or amelioration of a variety of medical conditions associated with neurological disorders using the compounds and compositions provided herein.
    Type: Application
    Filed: July 29, 2009
    Publication date: March 25, 2010
    Inventors: Linda C. Hsieh-Wilson, Sarah E. Tully, Ross Mabon, Cristal I. Gama
  • ANTIBODIES TO SULFATED CARBOHYDRATES
    Publication number: 20100071080
    Abstract: The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to chondroitin sulfate, particularly CS-A, CS-C and CS-E tetrasaccharides. The present invention also relates to methods of making anti-CS antibodies, pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for diagnosis and treatment.
    Type: Application
    Filed: July 29, 2009
    Publication date: March 18, 2010
    Inventors: Sarah E. Tully, Linda Hsieh-Wilson
  • Small molecule stimulators of neuronal growth
    Patent number: 7638503
    Abstract: Provided herein are small molecule stimulators of neuronal growth, their preparation, and their use for treatment of neurological disorders. In one embodiment, provided herein are methods of treatment, prevention, or amelioration of a variety of medical conditions associated with neurological disorders using the compounds and compositions provided herein.
    Type: Grant
    Filed: May 26, 2005
    Date of Patent: December 29, 2009
    Assignee: California Institute of Technology
    Inventors: Linda C. Hsieh-Wilson, Sarah E. Tully, Ross Mabon, Cristal I. Gama