Patents by Inventor Sarah GRUSZKA

Sarah GRUSZKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition of matter: engineering of phage K1E
    Patent number: 11268072
    Abstract: The present disclosure provides compositions including recombinant K1E bacteriophages, methods for making the same, and uses thereof. The recombinant K1E bacteriophages disclosed herein are useful for the identification and/or antibiotic susceptibility profiling of specific bacterial strains/species present in a sample.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: March 8, 2022
    Assignee: THE CHARLES STARK DRAPER LABORATORY, INC.
    Inventors: Sarah Gruszka, Jason Holder
  • Bacteriophage engineering methods
    Patent number: 10815535
    Abstract: The present disclosure provides methods and kits for generating recombinant bacteriophage genomes.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: October 27, 2020
    Assignee: The Charles Stark Draper Laboratory, Inc.
    Inventors: Jason Holder, Connor McBrine, Sarah Gruszka, Miles Rogers, Nicole Billings
  • COMPOSITION OF MATTER: ENGINEERING OF ESCHERICHIA COLI PHAGE K1E
    Publication number: 20190330599
    Abstract: The present disclosure provides compositions including recombinant K1E bacteriophages, methods for making the same, and uses thereof. The recombinant K1E bacteriophages disclosed herein are useful for the identification and/or antibiotic susceptibility profiling of specific bacterial strains/species present in a sample.
    Type: Application
    Filed: July 12, 2019
    Publication date: October 31, 2019
    Inventors: Sarah Gruszka, Jason Holder
  • Recombinant K and 812 bacteriophages and uses thereof
    Patent number: 10260083
    Abstract: The present disclosure provides compositions including recombinant K or 812 bacteriophages, methods for making the same, and uses thereof. The recombinant K or 812 bacteriophages disclosed herein are useful for the identification and/or antibiotic susceptibility profiling of specific bacterial strains/species present in a sample.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: April 16, 2019
    Assignee: THE CHARLES STARK DRAPER LABORATORY, INC.
    Inventors: Peter Cavanagh, Helen Bartlett, Kirsty A. McFarland, Nicole E. Raustad, Sarah Gruszka, Jason Holder
  • Composition of matter: engineering of phage K1E
    Patent number: 10174295
    Abstract: The present disclosure provides compositions including recombinant K1E bacteriophages, methods for making the same, and uses thereof. The recombinant K1E bacteriophages disclosed herein are useful for the identification and/or antibiotic susceptibility profiling of specific bacterial strains/species present in a sample.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: January 8, 2019
    Assignee: THE CHARLES STARK DRAPER LABORATORY, INC.
    Inventors: Sarah Gruszka, Jason Holder
  • Recombinant PB1 bacteriophages and uses thereof
    Patent number: 10174293
    Abstract: The present disclosure provides compositions including recombinant PB1 bacteriophages, methods for making the same, and uses thereof. The recombinant PB1 bacteriophages disclosed herein are useful for the identification and/or antibiotic susceptibility profiling of specific bacterial strains/species present in a sample.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: January 8, 2019
    Assignee: THE CHARLES STARK DRAPER LABORATORY, INC.
    Inventors: Sarah Gruszka, Parker Dow, Jason Holder
  • BACTERIOPHAGE ENGINEERING METHODS
    Publication number: 20170283779
    Abstract: The present disclosure provides methods and kits for generating recombinant bacteriophage genomes.
    Type: Application
    Filed: March 27, 2017
    Publication date: October 5, 2017
    Applicant: The Charles Stark Draper Laboratory, Inc.
    Inventors: JASON HOLDER, Connor McBrine, Sarah Gruszka, Miles Rogers, Nicole Billings
  • Method and System for Detection of an Organism
    Publication number: 20150344973
    Abstract: The invention provides, inter alia, systems, compositions, kits and methods for detecting an organism, such as a microbe, microorganism, pathogen, or organism associated with Hospital Associated Infections (HAIs). The systems, compositions, kits and methods can comprise one or more probes for detecting a strain with high sensitivity, high specificity, or both. The systems, compositions, kits and methods can also be used to detect the strain within a short time frame.
    Type: Application
    Filed: April 23, 2013
    Publication date: December 3, 2015
    Inventors: Philip Alexander ROLFE, Thomas CLARKE, IV, Sarah MAHONEY, Jack Thacher LEONARD, Sarah GRUSZKA