Abstract: This application discloses anti-CCR7 antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments. The invention also relates to methods of treating or preventing cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.

Abstract: The disclosure relates to novel compositions comprising 1) conditioned media, 2) combinations of secreted biomolecules/organic molecules, and/or 3) secreted extracellular vesicles/exosomes collected from differentiated epithelial cell culture, as well as methods of making and using such compositions.

Abstract: A device for electrically stimulating skin, in particular for stimulating the activity of fibroblasts, including an electronic circuit for generating a sawtooth biphasic or cyclic alternating electric current; at least two electrodes connected to the electronic circuit, which are configured so as to be applied to the skin in order to allow the electric current generated to pass therethrough.