Patents by Inventor Sarah Kasperbauer

Sarah Kasperbauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR PROMOTING NEURONAL OUTGROWTH
    Publication number: 20120207732
    Abstract: Neural outgrowth in the central nervous system is achieved by administering chondroitinase AC and/or chondroitinase B to degrade chondroitin sulfate proteoglycans that inhibit or contribute to the inhibition of nervous tissue regeneration.
    Type: Application
    Filed: April 20, 2012
    Publication date: August 16, 2012
    Inventors: Elliott A. GRUSKIN, Jennifer F. IACI, A. M. VECCHIONE, Sarah KASPERBAUER, Gargi ROY
  • Methods of purifying chondroitinase and stable formulations thereof
    Patent number: 8226941
    Abstract: An aspect of the present invention relates to stable formulations of chondroitinase and to methods of purifying chondroitinase. The methods of purifying chondroitinase includes the steps of extracting the enzyme from a cell, separating the chondroitinase from the crude cell extract using cation-exchange chromatography, removing impurities through gel filtration chromatography, and removing endotoxin through an anion-exchange membrane to produce a purified chondroitinase.
    Type: Grant
    Filed: May 18, 2005
    Date of Patent: July 24, 2012
    Assignee: Acorda Therapeutics, Inc.
    Inventors: Anthony O. Caggiano, Elliott A. Gruskin, Yelena G. Sheptovitsky, Sarah Kasperbauer
  • Methods of Purifying Chondroitinase and Stable Formulations Thereof
    Publication number: 20080311642
    Abstract: An aspect of the present invention relates to stable formulations of chondroitinase and to methods of purifying chondroitinase. The methods of purifying chondroitinase includes the steps of extracting the enzyme from a cell, separating the chondroitinase from the crude cell extract using cation-exchange chromatography, removing impurities through gel filtration chromatography, and removing endotoxin through an anion-exchange membrane to produce a purified chondroitinase.
    Type: Application
    Filed: May 18, 2005
    Publication date: December 18, 2008
    Applicant: ACORDA THERAPEUTICS, INC.
    Inventors: Anthony O. Caggiano, Elliott A. Gruskin, Yelena G. Sheptovitsky, Sarah Kasperbauer
  • Compositions and Methods for Promoting Neuronal Outgrowth
    Publication number: 20070274979
    Abstract: Neural outgrowth in the central nervous system is achieved by administering chondroitinase AC and/or chondroitinase B to degrade chondroitin sulfate proteoglycans that inhibit or contribute to the inhibition of nervous tissue regeneration.
    Type: Application
    Filed: May 5, 2003
    Publication date: November 29, 2007
    Inventors: Elliott Gruskin, Jennifer Iaci, A.M. Vecchione, Sarah Kasperbauer, Gargi Roy