Patents by Inventor Sarah L. Elson

Sarah L. Elson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Animal models and methods for analysis of lipid metabolism and screening of pharmaceutical and pesticidal agents that modulate lipid metabolism
    Patent number: 6781028
    Abstract: Drosophila melanogaster and C. elegans that have been genetically modified to express or mis-express proteins involved in the sterol regulatory element binding protein (SREBP) pathway are described. These genetically modified animal models have identifiable phenotypes that make them useful in assays for studying lipid metabolism, other genes implicated in lipid metabolism, and compounds capable of modulating lipid metabolism pathways. Methods for studying lipid metabolism in living nematodes using fluorescently-labelled fatty acid conjugates, such BODITY™ fatty acid conjugates, are also described. Novel SREBP pathway nucleic acid and protein sequences are also described.
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: August 24, 2004
    Assignee: Exelixis, Inc.
    Inventors: Michael R. Costa, Stephen K. Doberstein, Sarah L. Elson, Kimberly Carr Ferguson, Sheila Akiko Homburger