Patents by Inventor Sarah Liedke

Sarah Liedke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL ANTI-TROPONINT ANTIBODIES
    Publication number: 20220185874
    Abstract: The present invention relates to an improved variant monoclonal antibody binding to cardiac troponin T and having a better KD than the parent monoclonal antibody 11-7
    Type: Application
    Filed: February 8, 2022
    Publication date: June 16, 2022
    Inventors: Sarah LIEDKE, Frank KRONER, Michael SCHRAEML
  • METHOD FOR AFFINITY MATURATION OF ANTIBODIES
    Publication number: 20210009993
    Abstract: The present invention relates to a novel method of generating libraries of polynucleotides encoding a framework region and at least one adjacent complementarity determining region (CDR) of an antibody of interest. These libraries are suitable for use in affinity maturation procedures in order to obtain maturated antibodies with improved characteristics compared to the parent antibody.
    Type: Application
    Filed: September 9, 2020
    Publication date: January 14, 2021
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Frank Kroner, Michael Schraeml, Sarah Liedke
  • NOVEL ANTI-TROPONIN T ANTIBODIES
    Publication number: 20210009668
    Abstract: The present invention relates to improved variant monoclonal antibodies binding to cardiac troponin T and having a better KD than the monoclonal antibody 12.1A11.11-7, produced by hybridoma clone 7.1 A 12.2-22 (ECACC 89060901) as deposited with European Collection of Animal Cell Cultures, GB.
    Type: Application
    Filed: September 9, 2020
    Publication date: January 14, 2021
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Frank Kroner, Michael Schraeml, Sarah Liedke